- Insulin Degradation by Acinar Cell Proteases Creates a Dysfunctional Environment for Human Islets Before/After Transplantation: Benefits of alpha-1 Antitrypsin Treatment
[作者:Loganathan, G; Dawra, RK; Pugazhenthi, S; Guo, ZG; Soltani, SM; Wiseman, A; Sanders, MA; Papas, KK; Velayutham, K; Saluja, AK; Sutherland, DER; Hering, BJ; Balamurugan, AN,期刊:Transplantation, 页码:1222-1230 , 文章类型: Article,,卷期:2011年92-11]
- Background. Pancreatic acinar cells are commonly cotransplanted along with islets during auto-and allotransplantations. The aims of this study were to identify how acinar cell proteases cause human islet cell loss before...
- Reversal of Diabetes by the Creation of Neo-Islet Tissues Into a Subcutaneous Site Using Islet Cell Sheets
[作者:Saito, T; Ohashi, K; Utoh, R; Shimizu, H; Ise, K; Suzuki, H; Yamato, M; Okano, T; Gotoh, M,期刊:Transplantation, 页码:1231-1236 , 文章类型: Article,,卷期:2011年92-11]
- Background. There remains a paucity of therapeutic approaches to completely treat diabetes mellitus. This study was designed to develop a dispersed islet cell-based tissue engineering approach to engineer functional neo-...
- Association Between Age and Graft Failure Rates in Young Kidney Transplant Recipients
[作者:Foster, BJ; Dahhou, M; Zhang, X; Platt, RW; Samuel, SM; Hanley, JA,期刊:Transplantation, 页码:1237-1243 , 文章类型: Article,,卷期:2011年92-11]
- Background. Age at transplant and graft failure risk are associated in young kidney transplant recipients. The risk of graft failure may also vary by current age, irrespective of age at transplant. We sought to estimate ...
- Early Steroid Withdrawal and Optimization of Mycophenolic Acid Exposure in Kidney Transplant Recipients Receiving Mycophenolate Mofetil
[作者:Le Meur, Y; Thierry, A; Glowacki, F; Rerolle, JP; Garrigue, V; Ouali, N; Heng, AE; Delahousse, M; Albano, L; Lang, P; Couzi, L; Jaureguy, M; Lebranchu, Y; Mousson, C; Glotz, D; Kessler, M; Vrtovsnik, F; Rouanet, S; Tagieva, N; Kamar, N,期刊:Transplantation, 页码:1244-1251 , 文章类型: Article,,卷期:2011年92-11]
- Background. Early posttransplant steroid withdrawal may increase the risk of acute rejection and the occurrence of subclinical acute rejection (SCAR). We assessed the feasibility and safety of early steroid withdrawal in...
- Donor Desmopressin Is Associated With Superior Graft Survival After Kidney Transplantation
[作者:Benck, U; Gottmann, U; Hoeger, S; Lammert, A; Rose, D; Boesebeck, D; Lauchart, W; Birck, R; Weiss, C; Kramer, BK; Yard, BA; Schnuelle, P,期刊:Transplantation, 页码:1252-1258 , 文章类型: Article,,卷期:2011年92-11]
- Background. A recent randomized trial showed that pretreatment of the brain-dead donor with low-dose dopamine improves immediate kidney graft function, by limiting injury from cold storage (ClinicalTrials.gov Identifier:...
- Donor Graft Steatosis Influences Immunity to Hepatitis C Virus and Allograft Outcome After Liver Transplantation
[作者:Subramanian, V; Seetharam, AB; Vachharajani, N; Tiriveedhi, V; Angaswamy, N; Ramachandran, S; Crippin, JS; Shenoy, S; Chapman, WC; Mohanakumar, T; Anderson, CD,期刊:Transplantation, 页码:1259-1268 , 文章类型: Article,,卷期:2011年92-11]
- Background. Hepatitis C virus (HCV) recurrence after orthotopic liver transplantation (OLT) is universal, often with accelerated allograft fibrosis. Donor liver steatosis is frequently encountered and often associated wi...
- Current Status of Pediatric Intestinal Failure, Rehabilitation, and Transplantation: Summary of a Colloquium
[作者:Mazariegos, GV; Superina, R; Rudolph, J; Cohran, V; Burns, RC; Bond, GJ; Jaffe, R; Sindhi, R,期刊:Transplantation, 页码:1173-1180 , 文章类型: Article,,卷期:2011年92-11]
- An international symposium convened September 9-11, 2010, in Chicago to present the state of the art and science of the multidisciplinary care of intestinal failure in children. Medical and surgical management of the chi...
- Role of the Fc Region in CD70-Specific Antibody Effects on Cardiac Transplant Survival
[作者:Shariff, H; Greenlaw, RE; Meader, L; Gardner, N; Yagita, H; Coccia, M; Mamode, N; Jurcevic, S,期刊:Transplantation, 页码:1194-1201 , 文章类型: Article,,卷期:2011年92-11]
- Background. The role of the CD70-specific antibody and the mechanisms by which it extends transplant survival are not known. Methods. Fully major histocompatibility complex-mismatched heterotopic heart transplantation (B...
- Islet Graft Survival and Function: Concomitant Culture and Transplantation With Vascular Endothelial Cells in Diabetic Rats
[作者:Pan, XM; Xue, WJ; Li, Y; Feng, XS; Tian, XH; Ding, CG,期刊:Transplantation, 页码:1208-1214 , 文章类型: Article,,卷期:2011年92-11]
- Background. Human islet transplantation is a great potential therapy for type I diabetes. To investigate islet graft survival and function, we recently showed the improved effects after co-culture and co-transplantation ...
- Renal Protection From Prolonged Cold Ischemia and Warm Reperfusion in Hibernating Squirrels
[作者:Jani, A; Epperson, E; Martin, J; Pacic, A; Ljubanovic, D; Martin, SL; Edelstein, CL,期刊:Transplantation, 页码:1215-1221 , 文章类型: Article,,卷期:2011年92-11]
- Background. We have previously shown that cold ischemia (CI) results in massive increases in caspase-3 activity, tubular apoptosis, and brush border injury (BBI) in mouse kidneys. During hibernation, the 13-lined ground ...
- Novel Approach for Improved Assessment of Phenotypic and Functional Characteristics of BKV-Specific T-Cell Immunity
[作者:Trydzenskaya, H; Sattler, A; Muller, K; Schachtner, T; Dang-Heine, C; Friedrich, P; Nickel, P; Hoerstrup, J; Schindler, R; Thiel, A; Melzig, MF; Reinke, P; Babel, N,期刊:Transplantation, 页码:1269-1277 , 文章类型: Article,,卷期:2011年92-11]
- Background. BKV-associated nephropathy represents a serious complication of the posttransplant period in kidney transplant recipients. Monitoring BKV-specific immunity is of a special importance for estimation of clinica...
- Sex Differences in Deceased Donor Organ Transplantation Rates in the United States
[作者:Murugan, R; Sileanu, F; Wahed, AS; Al-Khafaji, A; Singbartl, K; Kellum, JA,期刊:Transplantation, 页码:1278-1284 , 文章类型: Article,,卷期:2011年92-11]
- Background. Greater numbers of organs transplanted from deceased male donors have been attributed to sex differences in the causes of death. Understanding sex differences in transplantation will help to design interventi...
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