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  • The evolution of MDM2 family genes
    [作者:Momand, J; Villegas, A; Belyi, VA,期刊:Gene, 页码:23-30 , 文章类型: Article,,卷期:2011年486-40910]
  • MDM2 and MDM4 are proto-oncoproteins that bind to and inhibit members of the p53 protein family, p53, p73 and possibly p63. p53 is a mammalian tumor suppressor and p63 and p73 are critical for development. With the seque...
  • Pseudotrisomy 13 syndrome: Use of homozygosity mapping to target candidate genes
    [作者:Marquis-Nicholson, R; Aftimos, S; Ashton, F; Love, JM; Stone, P; McFarlane, J; George, AM; Love, DR,期刊:Gene, 页码:37-40 , 文章类型: Article,,卷期:2011年486-40910]
  • Pseudotrisomy 13 syndrome is characterised by holoprosencephaly with or without polydactyly, but with a normal karyotype. The genetic cause of this syndrome remains unclear, but it is thought to be autosomal recessive. I...