- Decreased material-activation of the complement system using low-energy plasma polymerized poly(vinyl pyrrolidone) coatings
[作者:Andersen, TE; Palarasah, Y; Skjodt, MO; Ogaki, R; Benter, M; Alei, M; Kolmos, HJ; Koch, C; Kingshott, P,期刊:BIOMATERIALS, 页码:4481-4488 , 文章类型: Article,,卷期:2011年32-20]
- In the current study we investigate the activation of blood complement on medical device silicone rubber and present a plasma polymerized vinyl pyrrolidone (ppVP) coating which strongly decreases surface-activation of th...
- Neural lineage differentiation of embryonic stem cells within alginate microbeads
[作者:Li, LL; Davidovich, AE; Schloss, JM; Chippada, U; Schloss, RR; Langrana, NA; Yarmush, ML,期刊:BIOMATERIALS, 页码:4489-4497 , 文章类型: Article,,卷期:2011年32-20]
- Cell replacement therapies, using renewable stem cell sources, hold tremendous potential to treat a wide range of degenerative diseases. Although many studies have established techniques to successfully differentiate ste...
- One-dimensional self-assembly of mouse embryonic stem cells using an array of hydrogel microstrands
[作者:Raof, NA; Padgen, MR; Gracias, AR; Bergkvist, M; Xie, YB,期刊:BIOMATERIALS, 页码:4498-4505 , 文章类型: Article,,卷期:2011年32-20]
- The ability of embryonic stem (ES) cells to self-renew indefinitely and to differentiate into multiple cell lineages holds promise for advances in modeling disease progression, screening drugs and treating diseases. To r...
- Permanent protection of PLG scaffold transplanted allogeneic islet grafts in diabetic mice treated with ECDI-fixed donor splenocyte infusions
[作者:Kheradmand, T; Wang, SS; Gibly, RF; Zhang, XM; Holland, S; Tasch, J; Graham, JG; Kaufman, DB; Miller, SD; Shea, LD; Luo, XR,期刊:BIOMATERIALS, 页码:4517-4524 , 文章类型: Article,,卷期:2011年32-20]
- Allogeneic islet cell transplantation is a promising treatment for human type 1 diabetes. Currently, human islets are transplanted via intra-portal infusions. While successful, it leads to significant early islet attriti...
- Human treated dentin matrix as a natural scaffold for complete human dentin tissue regeneration
[作者:Li, R; Guo, WH; Yang, B; Guo, LJ; Sheng, L; Chen, G; Li, Y; Zou, Q; Xie, D; An, XX; Chen, Y; Tian, WD,期刊:BIOMATERIALS, 页码:4525-4538 , 文章类型: Article,,卷期:2011年32-20]
- An essential aspect of tooth tissue engineering is the identification of suitable scaffolding materials to support cell growth and tissue regeneration. Treated dentin matrix (TDM) from a rat has recently been shown to be...
- Long-term outcome of cryopreserved bone-derived osteoblasts for bone regeneration in vivo
[作者:Wang, SY; Zhang, WJ; Zhao, J; Ye, DX; Zhu, C; Yang, YH; Zhang, XL; Sun, XJ; Yang, C; Jiang, XQ; Zhang, ZY,期刊:BIOMATERIALS, 页码:4546-4555 , 文章类型: Article,,卷期:2011年32-20]
- Cryopreserved bone-derived osteoblasts (CBOs) have been considered as a promising cell source for bone regeneration. Previous studies have demonstrated that CBOs had good proliferation and osteogenicity. However, the lon...
- In vivo efficacy of an intratumorally injected in situ-forming doxorubicin/poly(ethylene glycol)-b-polycaprolactone diblock copolymer
[作者:Kang, YM; Kim, GH; Il Kim, J; Kim, DY; Lee, BN; Yoon, SM; Kim, JH; Kim, MS,期刊:BIOMATERIALS, 页码:4556-4564 , 文章类型: Article,,卷期:2011年32-20]
- The effectiveness of systemically administered anticancer treatments is limited by difficulties in achieving therapeutic doses within tumors, a problem that is complicated by dose-limiting side effects to normal tissue. ...
- The selective growth inhibition of oral cancer by iron core-gold shell nanoparticles through mitochondria-mediated autophagy
[作者:Wu, YN; Yang, LX; Shi, XY; Li, IC; Biazik, JM; Ratinac, KR; Chen, DH; Thordarson, P; Shieh, DB; Braet, F,期刊:BIOMATERIALS, 页码:4565-4573 , 文章类型: Article,,卷期:2011年32-20]
- Nanoparticles with an iron core and gold shell (denoted "Fe@AuO") have been reported to limit cancer-cell proliferation and therefore have been proposed as a potential anti-cancer agent. However, the underlying mechanism...
- Antitumor activity of liposomal ErbB2/HER2 epitope peptide-based vaccine constructs incorporating TLR agonists and mannose receptor targeting
[作者:Thomann, JS; Heurtault, B; Weidner, S; Braye, M; Beyrath, J; Fournel, S; Schuber, F; Frisch, B,期刊:BIOMATERIALS, 页码:4574-4583 , 文章类型: Article,,卷期:2011年32-20]
- Synthetic and molecularly defined constructs containing the minimal components to mimic and amplify the physiological immune response are able to induce an efficient cytotoxic response. In the current study this approach...
- Targeted dual-contrast T(1)- and T(2)-weighted magnetic resonance imaging of tumors using multifunctional gadolinium-labeled superparamagnetic iron oxide nanoparticles
[作者:Yang, H; Zhuang, YM; Sun, Y; Dai, AT; Shi, XY; Wu, DM; Li, FY; Hu, H; Yang, SP,期刊:BIOMATERIALS, 页码:4584-4593 , 文章类型: Article,,卷期:2011年32-20]
- Development of a multifunctional nanoparticle (NP) system allowing for dual-contrast T(1)- and T(2)-weighted targeted magnetic resonance (MR) imaging of tumors could significantly improve the diagnosis accuracy. In this ...
- Multifunctional and degradable zwitterionic nanogels for targeted delivery, enhanced MR imaging, reduction-sensitive drug release, and renal clearance
[作者:Zhang, L; Xue, H; Cao, ZQ; Keefe, A; Wang, JN; Jiang, SY,期刊:BIOMATERIALS, 页码:4604-4608 , 文章类型: Article,,卷期:2011年32-20]
- Multifunctional and degradable nanogels encapsulating both model drug (fluorescently labeled dextran) and imaging reagent (monodisperse Fe(3)O(4) nanoparticles) were developed by polymerizing zwitterionic monomers with a...
- The mechanism of enhancement on oral absorption of paclitaxel by N-octyl-O-sulfate chitosan micelles
[作者:Mo, R; Jin, X; Li, N; Ju, CY; Sun, MJ; Zhang, C; Ping, QN,期刊:BIOMATERIALS, 页码:4609-4620 , 文章类型: Article,,卷期:2011年32-20]
- The overall objective of the present investigation was to demonstrate the effect of N-octyl-O-sulfate chitosan (NOSC) micelles on enhancing the oral absorption of paclitaxel (PT)() in vivo and in vitro, and identify the ...
- Maltosylated polyethylenimine-based triple nanocomplexes of human papillomavirus 16L1 protein and DNA as a vaccine co-delivery system
[作者:Cho, HJ; Han, SE; Im, S; Lee, Y; Kim, YB; Chun, T; Oh, YK,期刊:BIOMATERIALS, 页码:4621-4629 , 文章类型: Article,,卷期:2011年32-20]
- To improve vaccine delivery, we herein designed a co-delivery system using a protein antigen and its encoding plasmid linked in nanocomplexes via maltosylated PEI (mPEI). Cationic mPEI was electrostatically complexed to ...
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