- Identification of a second CtBP binding site in adenovirus type 5 E1A conserved region 3
[作者:Bruton, RK; Pelka, P; Mapp, KL; Fonseca, GJ; Torchia, J; Turnell, AS; Mymryk, JS; Grand, RJA,期刊:Journal of virology, 页码:8476-8486 , 文章类型: Article,,卷期:2008年82-17]
- C-terminal binding protein (CtBP) binds to adenovirus early region 1A (AdE1A) through a highly conserved PXDLS motif close to the C terminus. We now have demonstrated that CtBP1 also interacts directly with the transcrip...
- Targeting the apoptotic pathway with BCL-2 inhibitors sensitizes primary chronic lymphocytic leukemia cells to vesicular stomatitis virus-induced oncolysis
[作者:Tumilasci, VF; Oliere, S; Nguyen, TLA; Shamy, A; Bell, J; Hiscott, J,期刊:Journal of virology, 页码:8487-8499 , 文章类型: Article,,卷期:2008年82-17]
- Chronic lymphocytic leukemia (CLL) is characterized by clonal accumulation of CD5(+) CD19(+) B lymphocytes that are arrested in the G,VG, phase of the cell cycle and fail to undergo apoptosis because of overexpression of...
- West Nile virus nonstructural protein 1 inhibits TLR3 signal transduction
[作者:Wilson, JR; de Sessions, PF; Leon, MA; Scholle, F,期刊:Journal of virology, 页码:8262-8271 , 文章类型: Article,,卷期:2008年82-17]
The innate immune response is the first line of defense against foreign pathogens. The recognition of virus-associated molecular patterns, including double- and single-stranded RNA, by pattern recognition receptors in...
- Effects of hemagglutinin-neuraminidase protein mutations on cell-cell fusion mediated by human parainfluenza type 2 virus
[作者:Tsurudome, M; Nishio, M; Ito, M; Tanahashi, S; Kawano, M; Komada, H; Ito, Y,期刊:Journal of virology, 页码:8283-8295 , 文章类型: Article,,卷期:2008年82-17]
- The monoclonal antibody M1-1A, specific for the hemagglutinin-neuraminidase (HN) protein of human parainfluenza type 2 virus (HPIV2), blocks virus-induced cell-cell fusion without affecting the hemagglutinating and neura...
- Measles virus circumvents the host interferon response by different actions of the C and V proteins
[作者:Nakatsu, Y; Takeda, M; Ohno, S; Shirogane, Y; Iwasaki, M; Yanagi, Y,期刊:Journal of virology, 页码:8296-8306 , 文章类型: Article,,卷期:2008年82-17]
- Measles is an acute febrile infectious disease with high morbidity and mortality. The genome of measles virus (MV), the causative agent, encodes two accessory products, V and C proteins, that play important roles in MV v...
- CD81 is a central regulator of cellular events required for hepatitis C virus infection of human hepatocytes
[作者:Brazzoli, M; Bianchi, A; Filippini, S; Weiner, A; Zhu, Q; Pizza, M; Crotta, S,期刊:Journal of virology, 页码:8316-8329 , 文章类型: Article,,卷期:2008年82-17]
- Infection with hepatitis C virus (HCV) is still a major public health problem, and the events leading to hepatocyte infection are not yet fully understood. Combining confocal microscopy with biochemical analysis and stud...
- Intramembrane processing by signal peptide peptidase regulates the membrane localization of hepatitis C virus core protein and viral propagation
[作者:Okamoto, K; Mori, Y; Komoda, Y; Okamoto, T; Okochi, M; Takeda, M; Suzuki, T; Moriishi, K; Matsuura, Y,期刊:Journal of virology, 页码:8349-8361 , 文章类型: Article,,卷期:2008年82-17]
- Hepatitis C virus (HCV) core protein has shown to be localized in the detergent-resistant membrane (DRM), which is distinct from the classical raft fraction including caveolin, although the biological significance of the...
- Differential requirements of the C terminus of Nbs1 in suppressing adenovirus DNA replication and promoting concatemer formation
[作者:Lakdawala, SS; Schwartz, RA; Ferenchak, K; Carson, CT; McSharry, BP; Wilkinson, GW; Weitzman, MD,期刊:Journal of virology, 页码:8362-8372 , 文章类型: Article,,卷期:2008年82-17]
- Adenoviruses (Ad) with the early region E4 deleted (E4-deleted virus) are defective for DNA replication and late protein synthesis. Infection with E4-deleted viruses results in activation of a DNA damage response, accumu...
- Human immunodeficiency virus type 1 Nef expression prevents AP-2-mediated internalization of the major histocompatibility complex class II-associated invariant chain
[作者:Toussaint, H; Gobert, FX; Schindler, M; Banning, C; Kozik, P; Jouve, M; Kirchhoff, F; Benaroch, P,期刊:Journal of virology, 页码:8373-8382 , 文章类型: Article,,卷期:2008年82-17]
- The lentiviral Nef protein has been studied extensively for its ability to induce the downregulation of several immunoreceptors on the surfaces of infected cells. However, Nef expression is unique in inducing highly effe...
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