- IL-19, IL-20 and IL-24: potential therapeutic targets for autoimmune diseases
[作者:Leng, RX; Pan, HF; Tao, JH; Ye, DQ,期刊:Expert Opinion on Therapeutic Targets, 页码:119-126 , 文章类型: Article,,卷期:2011年15-2]
- IL-19, IL-20 and IL-24 are members of the IL-10 family of cytokines, the human IL-19, IL-20 and IL-24 genes are all located on the q32 region of chromosome 1, and the three cytokines also share a common receptor IL-20R1/...
- Non-histone nuclear factor HMGB1 as a therapeutic target in colorectal cancer
[作者:Ohmori, H; Luo, Y; Kuniyasu, H,期刊:Expert Opinion on Therapeutic Targets, 页码:183-193 , 文章类型: Review,,卷期:2011年15-2]
- Introduction: High-motility group box (HMGB)-1 is the focus of recent cancer research. HMGB1 plays a critical role in cancer development, progression, and metastasis by activation of cancer cells, enhancement of tumor an...
- Targeting liver X receptors in human health: deadlock or promising trail?
[作者:Viennois, E; Pommier, AJC; Mouzat, K; Oumeddour, A; El Hajjaji, FZ; Dufour, J; Caira, F; Volle, DH; Baron, S; Lobaccaro, JMA,期刊:Expert Opinion on Therapeutic Targets, 页码:219-232 , 文章类型: Review,,卷期:2011年15-2]
- Introduction: Liver X receptors (LXR) are transcription factors that belong to the nuclear receptor superfamily. Natural derivatives of cholesterol, known as oxysterols, have been identified as agonistic ligands of LXR. ...
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