- Identification of the structural motif responsible for trimeric assembly of the C-terminal regulatory domains of polycystin channels PKD2L1 and PKD2
[作者:Molland, KL; Narayanan, A; Burgner, JW; Yernool, DA,期刊:Biochemical Journal, 页码:171-183 , 文章类型: Article,,卷期:2010年429-Part 1]
- Polycystin 2-type cation channels PKD2 and PKD2L1 interact with polycystin 1-type proteins PKD1 and PKD1L3 respectively, to form receptor cation-channel complexes. The PKD2L1-PKD1L3 complex perceives sour taste, whereas ...
- Temporal regulation of Cat-1 (cationic amino acid transporter-1) gene transcription during endoplasmic reticulum stress
[作者:Huang, CC; Li, Y; Lopez, AB; Chiang, CM; Kaufman, RJ; Snider, MD; Hatzoglou, M,期刊:Biochemical Journal, 页码:215-224 , 文章类型: Article,,卷期:2010年429-Part 1]
- Expression of the Cat-1 gene (cationic amino acid transporter-1) is induced in proliferating cells and in response to a variety of stress conditions. The expression of the gene is mediated via a TATA-less promoter. In th...
- Pyruvate dehydrogenase kinase 1 controls mitochondrial metabolism and insulin secretion in INS-1 832/13 clonal beta-cells
[作者:Krus, U; Kotova, O; Spegel, P; Hallgard, E; Sharoyko, VV; Vedin, A; Moritz, T; Sugden, MC; Koeck, T; Mulder, H,期刊:Biochemical Journal, 页码:205-213 , 文章类型: Article,,卷期:2010年429-Part 1]
- Tight coupling between cytosolic and mitochondrial metabolism is key for GSIS (glucose-stimulated insulin secretion). In the present study we examined the regulatory contribution of PDH (pyruvate dehydrogenase) kinase 1,...
- Roles of COMM-domain-containing 1 in stability and recruitment of the copper-transporting ATPase in a mouse hepatoma cell line
[作者:Miyayama, T; Hiraoka, D; Kawaji, F; Nakamura, E; Suzuki, N; Ogra, Y,期刊:Biochemical Journal, 页码:53-61 , 文章类型: Article,,卷期:2010年429-Part 1]
- A novel function of COMMD1 {COMM [copper metabolism MURR1 (mouse U2af1-rs1 region 1)]-domain-containing 1}, a protein relevant to canine copper toxicosis, was examined in the mouse hepatoma cell line Hepa 1-6 with multi-...
- Regulation of Nicotiana tabacum osmotic stress-activated protein kinase and its cellular partner GAPDH by nitric oxide in response to salinity
[作者:Wawer, I; Bucholc, M; Astier, J; Anielska-Mazur, A; Dahan, J; Kulik, A; Wyslouch-Cieszynska, A; Zareba-Koziol, M; Krzywinska, E; Dadlez, M; Dobrowolska, G; Wendehenne, D,期刊:Biochemical Journal, 页码:73-83 , 文章类型: Article,,卷期:2010年429-Part 1]
- Several studies focusing on elucidating the mechanism of NO (nitric oxide) signalling in plant cells have highlighted that its biological effects are partly mediated by protein kinases. The identity of these kinases and ...
- Selenium compounds are substrates for glutaredoxins: a novel pathway for selenium metabolism and a potential mechanism for selenium-mediated cytotoxicity
[作者:Wallenberg, M; Olm, E; Hebert, C; Bjornstedt, M; Fernandes, AP,期刊:Biochemical Journal, 页码:85-93 , 文章类型: Article,,卷期:2010年429-Part 1]
- The Grx (glutaredoxin) proteins are oxidoreductases with a central function in maintaining the redox balance within the cell. In the present study, we have explored the reactions between selenium compounds and the glutar...
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