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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共24条记录   ApoCIII-Enriched LDL in Type 2 Diabetes Displays Altered Lipid Composition, Increased Susceptibility for Sphingomyelinase, and Increased Binding to Biglycan [作者：Hiukka, A; Stahlman, M; Pettersson, C; Levin, M; Adiels, M; Teneberg, S; Leinonen, ES; Hulten, LM; Wiklund, O; Oresic, M; Olofsson, SO; Taskinen, MR; Ekroos, K; Boren, J,期刊：Diabetes, 页码：2018-2026 , 文章类型： Article，,卷期：2009年58-9] OBJECTIVE-Apolipoprotein CIII (apoCIII) is an independent risk factor for cardiovascular disease, but the molecular mechanisms involved are poorly understood. We investigated potential proatherogenic properties of apoCII... Prediction of Metabolic Syndrome by Low Serum Testosterone Levels in Men Results From the Study of Health in Pomerania [作者：Haring, R; Volzke, H; Felix, SB; Schipf, S; Dorr, M; Rosskopf, D; Nauck, M; Schofl, C; Wallaschofski, H,期刊：Diabetes, 页码：2027-2031 , 文章类型： Article，,卷期：2009年58-9] OBJECTIVE-The aim of this analysis was to assess the prospective association of serum testosterone and dehydroepiandrosterone sulfate (DHEAS) levels with incident metabolic syndrome (MetS) in men. RESEARCH DESIGN AND MET... Resistin-Like Molecule-beta Inhibits SGLT-1 Activity and Enhances GLUT2-Dependent Jejunal Glucose Transport [作者：Krimi, RB; Letteron, P; Chedid, P; Nazaret, C; Ducroc, R; Marie, JC,期刊：Diabetes, 页码：2032-2038 , 文章类型： Proceedings Paper，,卷期：2009年58-9] OBJECTIVE-An increased expression of RELM-beta (resistin-like molecule-beta), a gut-derived hormone, is observed in animal models of insulin resistance/obesity and intestinal inflammation. Intestinal sugar absorption is ... SH2B1 Enhances Insulin Sensitivity by Both Stimulating the Insulin Receptor and Inhibiting Tyrosine Dephosphorylation of Insulin Receptor Substrate Proteins [作者：Morris, DL; Cho, KW; Zhou, YJ; Rui, LY,期刊：Diabetes, 页码：2039-2047 , 文章类型： Article，,卷期：2009年58-9] OBJECTIVE-SH2B1 is a SH2 domain-containing adaptor protein expressed in both the central nervous system and peripheral tissues. Neuronal SH2B1 controls body weight; however, the functions of peripheral SH2B1 remain unkno... Islet-1 is Required for the Maturation, Proliferation, and Survival of the Endocrine Pancreas [作者：Du, AP; Hunter, CS; Murray, J; Noble, D; Cai, CL; Evans, SM; Stein, R; May, CL,期刊：Diabetes, 页码：2059-2069 , 文章类型： Article，,卷期：2009年58-9] OBJECTIVE-The generation of mature cell types during pancreatic development depends on the expression of many regulatory and signaling proteins. In this study, we tested the hypothesis that the transcriptional regulator ... Involvement of Per-Arnt-Sim Kinase and Extracellular-Regulated Kinases-1/2 in Palmitate Inhibition of Insulin Gene Expression in Pancreatic beta-Cells [作者：Fontes, G; Semache, M; Hagman, DK; Tremblay, C; Shah, R; Rhodes, CJ; Rutter, J; Poitout, V,期刊：Diabetes, 页码：2048-2058 , 文章类型： Article，,卷期：2009年58-9] OBJECTIVE-Prolonged exposure of pancreatic beta-cells to simultaneously elevated levels of fatty acids and glucose (glucolipotoxicity) impairs insulin gene transcription. However, the intracellular signaling pathways med... Insulin Storage and Glucose Homeostasis in Mice Null for the Granule Zinc Transporter ZnT8 and Studies of the Type 2 Diabetes-Associated Variants [作者：Nicolson, TJ; Bellomo, EA; Wijesekara, N; Loder, MK; Baldwin, JM; Gyulkhandanyan, AV; Koshkin, V; Tarasov, AI; Carzaniga, R; Kronenberger, K; Taneja, TK; Xavier, GD; Libert, S; Froguel, P; Scharfmann, R; Stetsyuk, V; Ravassard, P; Parker, H; Gribble, FM; Reimann, F; Sladek, R; Hughes, SJ; Johnson, PRV; Masseboeuf, M; Burcelin, R; Baldwin, SA; Liu, M; Lara-Lemus, R; Arvan, P; Schuit, FC; Wheeler, MB; Chimienti, F; Rutter, GA,期刊：Diabetes, 页码：2070-2083 , 文章类型： Article，,卷期：2009年58-9] OBJECTIVE-Zinc ions are essential for the formation of hexameric insulin and hormone crystallization. A nonsynonymous single nucleotide polymorphism rs13266634 in the SLC30A8 gene, encoding the secretory granule zinc tra... Urinary Adiponectin Excretion A Novel Marker for Vascular Damage in Type 2 Diabetes [作者：von Eynatten, M; Liu, D; Hock, C; Oikonomou, D; Baumann, M; Allolio, B; Korosoglou, G; Morcos, M; Campean, V; Amann, K; Lutz, J; Heemann, U; Nawroth, PP; Bierhans, A; Humpert, PM,期刊：Diabetes, 页码：2093-2099 , 文章类型： Article，,卷期：2009年58-9] OBJECTIVE-Markers reliably identifying vascular damage and risk in diabetic patients are rare, and reports on associations of serum adiponectin with macrovascular disease have been inconsistent. In contrast to existing d... Insulin Granule Recruitment and Exocytosis Is Dependent on p110 gamma in Insulinoma and Human beta-Cells [作者：Pigeau, GM; Kolic, J; Ball, BJ; Hoppa, MB; Wang, YW; Ruckle, T; Woo, M; Fox, JEM; MacDonald, PE,期刊：Diabetes, 页码：2084-2092 , 文章类型： Article，,卷期：2009年58-9] OBJECTIVE-Phosphatidylinositol 3-OH kinase (PI3K) has a long-recognized role in beta-cell mass regulation and gene transcription and is implicated in the modulation of insulin secretion. The role of nontyrosine kinase re... Effects of Differing Antecedent Increases of Plasma Cortisol on Counterregulatory Responses During Subsequent Exercise in Type 1 Diabetes [作者：Bao, SC; Briscoe, VJ; Tate, DB; Davis, SN,期刊：Diabetes, 页码：2100-2108 , 文章类型： Proceedings Paper，,卷期：2009年58-9] OBJECTIVE-Antecedent hypoglycemia can blunt neuroendocrine and autonomic nervous system responses to next-day exercise in type 1 diabetes. The aim of this study was to determine whether antecedent increase of plasma cort... Adipose Tissue Expression and Genetic Variants of the Bone Morphogenetic Protein Receptor 1A Gene (BMPR1A) Are Associated With Human Obesity [作者：Bottcher, Y; Unbehauen, H; Kloting, N; Ruschke, K; Korner, A; Schleinitz, D; Tonjes, A; Enigk, B; Wolf, S; Dietrich, K; Koriath, M; Scholz, GH; Tseng, YH; Dietrich, A; Schon, MR; Kiess, W; Stumvoll, M; Bluher, M; Kovacs, P,期刊：Diabetes, 页码：2119-2128 , 文章类型： Article，,卷期：2009年58-9] OBJECTIVE-Members of the family of bone morphogenetic proteins (BMPs) are important regulators of adipogenesis. We examined the role of the BMP receptor 1A gene (BMPR1A) in the pathophysiology of human obesity. RESEARCH ... Effect of the Monocyte Chemoattractant Protein-1/CC Chemokine Receptor 2 System on Nephrin Expression in Streptozotocin-Treated Mice and Human Cultured Podocytes [作者：Tarabra, E; Giunti, S; Barutta, F; Salvidio, G; Burt, D; Deferrari, G; Gambino, R; Vergola, D; Pinach, S; Perin, PC; Camussi, G; Gruden, G,期刊：Diabetes, 页码：2109-2118 , 文章类型： Article，,卷期：2009年58-9] OBJECTIVE-Monocyte chemoattractant protein-1 (MCP-1), a chemokine binding to the CC chemokine receptor 2 (CCR2) and promoting monocyte infiltration, has been implicated in the pathogenesis of diabetic nephropathy. To ass... A Systematic Meta-Analysis of Genetic Association Studies for Diabetic Retinopathy [作者：Abhary, S; Hewitt, AW; Burdon, KP; Craig, JE,期刊：Diabetes, 页码：2137-2147 , 文章类型： Article，,卷期：2009年58-9] OBJECTIVE-Diabetic retinopathy is a sight-threatening microvascular complication of diabetes with a complex multifactorial pathogenesis. A systematic meta-analysis was undertaken to collectively assess genetic studies an... Association of 18 Confirmed Susceptibility Loci for Type 2 Diabetes With Indices of Insulin Release, Proinsulin Conversion, and Insulin Sensitivity in 5,327 Nondiabetic Finnish Men [作者：Stancakova, A; Kuulasmaa, T; Paananen, J; Jackson, AU; Bonnycastle, LL; Collins, FS; Boehnke, M; Kuusisto, J; Laakso, M,期刊：Diabetes, 页码：2129-2136 , 文章类型： Article，,卷期：2009年58-9] OBJECTIVE-We investigated the effects of 18 confirmed type 2 diabetes risk single nucleotide polymorphisms (SNPs) on insulin sensitivity, insulin secretion, and conversion of proinsulin to insulin. RESEARCH DESIGN AND ME... Glucagon-Like Peptide-1 Receptor Activation Modulates Pancreatitis-Associated Gene Expression But Does Not Modify the Susceptibility to Experimental Pancreatitis in Mice [作者：Koehler, JA; Baggio, LL; Lamont, BJ; Ali, S; Drucker, DJ,期刊：Diabetes, 页码：2148-2161 , 文章类型： Article，,卷期：2009年58-9] OBJECTIVE-Clinical reports link use of the glucagon-like peptide-1 receptor (GLP-1R) agonists exenatide and liraglutide to pancreatitis. However, whether these agents act on the exocrine pancreas is poorly understood. RE... Antigen-Based Therapy for the Treatment of Type 1 Diabetes [作者：Tian, J; Kaufman, DL,期刊：Diabetes, 页码：1939-1946 , 文章类型： Article，,卷期：2009年58-9]