- Expression of Fyn Kinase Modulates EMT in Oral Cancer Cells
[作者:Lewin, B; Siu, A; Baker, C; Dang, DM; Schnitt, R; Eisapooran, P; Ramos, DM,期刊:Anticancer Research, 页码:2591-2596 , 文章类型: Article,,卷期:2010年30-7]
- Oral squamous cell carcinoma (SCC) is an aggressive tumor with a poor 5-year survival rate. Oral SCC can undergo epithelial to mesenchymal transition (EMT). We previously showed that the epithelial integrin alpha v beta ...
- SMAD4 Mediates Mesenchymal-Epithelial Reversion in SW480 Colon Carcinoma Cells
[作者:Pohl, M; Radacz, Y; Pawlik, N; Schoeneck, A; Baldus, SE; Munding, J; Schmiegel, W; Schwarte-Waldhoff, I; Reinacher-Schick, A,期刊:Anticancer Research, 页码:2603-2613 , 文章类型: Article,,卷期:2010年30-7]
- Background: Inactivation of the tumour suppressor gene SMAD4 is a genetically late event in gastrointestinal carcinogenesis. SMAD4 is a transmitter of growth-inhibitory effects of transforming growth factor-beta (TGF-bet...
- Bone Destruction by Invading Oral Squamous Carcinoma Cells Mediated by the Transforming Growth Factor-beta Signalling Pathway
[作者:Goda, T; Shimo, T; Yoshihama, Y; Hassan, NMM; Ibaragi, S; Kurio, N; Okui, T; Honami, T; Kishimoto, K; Sasaki, A,期刊:Anticancer Research, 页码:2615-2623 , 文章类型: Article,,卷期:2010年30-7]
- Background: Gingival squamous cell carcinoma (SCC) cells frequently invade mandibular bone, and this destruction is associated with a worse prognosis. However, the relationship between bone destruction and associated fac...
- Combination Therapy of 5-Fluorouracil with Rapamycin for Hormone Receptor-negative Human Breast Cancer
[作者:Hosono, Y; Osada, S; Nawa, M; Takahashi, T; Yamaguchi, K; Kawaguchi, Y; Yoshida, K,期刊:Anticancer Research, 页码:2625-2630 , 文章类型: Article,,卷期:2010年30-7]
- Aim: To determine a novel chemotherapeutic concept for hormone receptor-negative and HER2-positive breast cancer, a high progression form of the disease for which treatment has been difficult. A combination therapy of 5-...
- gamma-Tocotrienol Controls Proliferation, Modulates Expression of Cell Cycle Regulatory Proteins and Up-regulates Quinone Reductase NQO2 in MCF-7 Breast Cancer Cells
[作者:Hsieh, TC; Elangovan, S; Wu, JM,期刊:Anticancer Research, 页码:2869-2874 , 文章类型: Article,,卷期:2010年30-7]
- Background: Tocotrienols, a subgroup of the vitamin E family, have demonstrated antioxidant and anticancer properties. Differential growth responses among different types of tocotrienols have been observed in breast canc...
- The Influence of Cyclin D1 A870G Polymorphism on Colorectal Cancer Risk and Prognosis in a Turkish Population
[作者:Yaylim-Eraltan, I; Arikan, S; Yildiz, Y; Cacina, C; Ergen, HA; Tuna, G; Gormus, U; Zeybek, U; Isbir, T,期刊:Anticancer Research, 页码:2875-2880 , 文章类型: Article,,卷期:2010年30-7]
- Background: Cyclin D1, encoded by the gene CCND1, is a regulatory protein in the cell cycle transition from G(1) phase to S phase. A common polymorphism (A870G) at codon 242 affects splicing of the CCND1 transcript and m...
- Identification of a Tumour Associated Antigen in Lung Cancer Patients with Asbestos Exposure
[作者:Yasuda, M; Hanagiri, T; Shigematsu, Y; Onitsuka, T; Kuroda, K; Baba, T; Mizukami, M; Ichiki, Y; Uramoto, H; Takenoyama, M; Yasumoto, K,期刊:Anticancer Research, 页码:2631-2639 , 文章类型: Article,,卷期:2010年30-7]
- Background: This study analysed the humoral immune response in asbestos exposed lung cancer patients to identify new surrogate markers of the carcinogenic risk in populations exposed to asbestos. Methods and Results: A s...
- Retrovirus-mediated Drosophila melanogaster Multisubstrate Deoxyribonucleoside Kinase Gene Therapy of Gastric Cancer Cells In Vitro and In Vivo
[作者:Zhu, Z; Zhao, L; He, AN; Huang, BJ; Karlsson, A; Xu, HM; Zheng, XY,期刊:Anticancer Research, 页码:2641-2649 , 文章类型: Article,,卷期:2010年30-7]
- Aim: The cytotoxicity of the Drosophila melanogaster multisubstrate deoxyribonucleoside kinase. (Dm-dNK)/nucleoside analog system to human gastric carci-noma cells was evaluated in vitro and in vivo for the development o...
- Epithelial Versus Endothelial CEACAM1 Expression and Angiogenesis in Epididymal Adenomatoid Tumor
[作者:Kilic, N; Tilki, D; Ergun, B; Seitz, M; Stief, CG; Reich, O; Ergun, S,期刊:Anticancer Research, 页码:2651-2657 , 文章类型: Article,,卷期:2010年30-7]
- Background/Aim: To study the expression of the pro-angiogenic factor carcinoembryonic antigen-related cell adhesion molecule-1 (CEACAM1) in epididymal adeno-matoid tumor tissue, a very rare benign neoplasia, in relation ...
- Combined Effect of CYP1B1 Codon 432 Polymorphism and N-Acetyltransferase 2 Slow Acetylator Phenotypes in Relation to Breast Cancer in the Turkish Population
[作者:Ozbek, YK; Ozturk, T; Tuzuner, BM; Calay, Z; Ilvan, S; Seyhan, FM; Kisakesen, HI; Ozturk, O; Isbir, T,期刊:Anticancer Research, 页码:2885-2889 , 文章类型: Article,,卷期:2010年30-7]
- Background: Breast cancer (BC), is more prevalent in subjects who have had prolonged exposure to heterocyclic amines, aromatic amines and high levels of oestradiol. Cytochrome P450 1B1 (CYP1B1) and N-acetyltransferase2 (...
- The Efficacy of Imiquimod on Dysplastic Lesions of the Oral Mucosa: An Experimental Model
[作者:Gkoulioni, V; Eleftheriadou, A; Yiotakis, I; Ferekidou, E; Chrisovergis, A; Lazaris, AC; Kandiloros, D,期刊:Anticancer Research, 页码:2891-2896 , 文章类型: Article,,卷期:2010年30-7]
- Aim: To study the potent efficacy of the immunomodulatory agent imiquimod when applied on dysplastic lesions of the oral mucosa. Materials and Methods: Carcinogen (DMBA) was applied to the mucosa of the left buccal pouch...
- Calcitriol Down-regulates Human Ether a go-go 1 Potassium Channel Expression in Cervical Cancer Cells
[作者:Avila, E; Garcia-Becerra, R; Rodriguez-Rasgado, JA; Diaz, L; Ordaz-Rosado, D; Zugel, U; Steinmeyer, A; Barrera, D; Halhali, A; Larrea, F; Camacho, J,期刊:Anticancer Research, 页码:2667-2672 , 文章类型: Article,,卷期:2010年30-7]
- Background/Aim: Human ether a-go-go-1 (EAG1) potassium channels are promising anticancer targets. Calcitriol has antitumoural properties. This study investigated EAG1 regulation by calcitriol in normal and cancer cells. ...
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