- Enhanced TLR4 endothelial cell immunohistochemical expression in symptomatic carotid atherosclerotic plaques
[作者:Katsargyris, A; Theocharis, SE; Tsiodras, S; Giaginis, K; Bastounis, E; Klonaris, C,期刊:Expert Opinion on Therapeutic Targets, 页码:1-10 , 文章类型: Article,,卷期:2010年14-1]
- Background and Purpose: Toll-like receptor-4 (TLR4) has been linked to the pathogenesis of atherosclerosis. Carotid atheroma endothelial cells (ECs) express TLR4, nevertheless correlations with cerebrovascular symptomato...
- Modulation of the renin-angiotensin-aldosterone system in sepsis: a new therapeutic approach?
[作者:Salgado, DR; Rocco, JR; Silva, E; Vincent, JL,期刊:Expert Opinion on Therapeutic Targets, 页码:11-20 , 文章类型: Review,,卷期:2010年14-1]
- Importance of the field: Severe sepsis is characterized by relative hypotension associated with a high cardiac output, peripheral vasodilation, and organ dysfunction. The renin-angiotensin-aldosterone system (RAAS) is pr...
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