- Targeting mitochondrial dysfunction in neurodegenerative disease: Part II
[作者:Burchell, VS; Gandhi, S; Deas, E; Wood, NW; Abramov, AY; Plun-Favreau, H,期刊:Expert Opinion on Therapeutic Targets, 页码:497-511 , 文章类型: Review,,卷期:2010年14-5]
- Areas covered in this review: This review examines the role of mitochondrial dysfunction in neurodegeneration, drawing examples from common diseases such as Alzheimer's disease and rarer familial disorders such as Charco...
- Targeting sphingolipid metabolism in head and neck cancer: rational therapeutic potentials
[作者:Beckham, TH; Elojeimy, S; Cheng, JC; Turner, LS; Hoffman, SR; Norris, JS; Liu, X,期刊:Expert Opinion on Therapeutic Targets, 页码:529-539 , 文章类型: Review,,卷期:2010年14-5]
- Importance of the field: Ceramide accumulation has been shown to be a conserved mechanism of apoptosis initiation in normal physiological processes as well as in response to cancer treatments. Therefore, it is unsurprisi...
- Circadian rhythms, adrenergic hormones and trafficking of hematopoietic stem cells
[作者:Giudice, A; Caraglia, M; Marra, M; Montella, M; Maurea, N; Abbruzzese, A; Arra, C,期刊:Expert Opinion on Therapeutic Targets, 页码:567-575 , 文章类型: Review,,卷期:2010年14-5]
- Areas covered in this review: It has been shown that circulating HSCs exhibit marked circadian fluctuations due to standard cycles of 12 h light/12 h darkness. Circadian HSCs oscillations are strongly altered when mice a...
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