- Monoclonal Antibody-Mediated Targeting of CD123, IL-3 Receptor alpha Chain, Eliminates Human Acute Myeloid Leukemic Stem Cells
[作者：Jin, LQ; Lee, EM; Ramshaw, HS; Busfield, SJ; Peoppl, AG; Wilkinson, L; Guthridge, MA; Thomas, D; Barry, EF; Boyd, A; Gearing, DP; Vairo, G; Lopez, AF; Dick, JE; Lock, RB,期刊：Cell Stem Cell, 页码：31-42 , 文章类型： Article，,卷期：2009年5-1]
- Leukemia stem cells (LSCs) initiate and sustain the acute myeloid leukemia (AML) clonal hierarchy and possess biological properties rendering them resistant to conventional chemotherapy. The poor survival of AML patients...
- TEL-AML1 Corrupts Hematopoietic Stem Cells to Persist in the Bone Marrow and Initiate Leukemia
[作者：Schindler, JW; Van Buren, D; Foudi, A; Krejci, O; Qin, JZ; Orkin, SH; Hock, H,期刊：Cell Stem Cell, 页码：43-53 , 文章类型： Article，,卷期：2009年5-1]
- The initial steps in the pathogenesis of acute leukemia remain incompletely understood. The TEL-AML1 gene fusion, the hallmark translocation in Childhood Acute Lymphoblastic Leukemia and the first hit, occurs years befor...
- Intravenous hMSCs Improve Myocardial Infarction in Mice because Cells Embolized in Lung Are Activated to Secrete the Anti-inflammatory Protein TSG-6
[作者：Lee, RH; Pulin, AA; Seo, MJ; Kota, DJ; Ylostalo, J; Larson, BL; Semprun-Prieto, L; Delafontaine, P; Prockop, DJ,期刊：Cell Stem Cell, 页码：54-63 , 文章类型： Article，,卷期：2009年5-1]
- Quantitative assays for human DNA and mRNA were used to examine the paradox that intravenously (i.v.) infused human multipotent stromal cells (hMSCs) can enhance tissue repair without significant engraftment. After 2 x 1...
- Gene Targeting of a Disease-Related Gene in Human Induced Pluripotent Stem and Embryonic Stem Cells
[作者：Zou, JZ; Maeder, ML; Mali, P; Pruett-Miller, SM; Thibodeau-Beganny, S; Chou, BK; Chen, GB; Ye, ZH; Park, IH; Daley, GQ; Porteus, MH; Joung, JK; Cheng, L,期刊：Cell Stem Cell, 页码：97-110 , 文章类型： Article，,卷期：2009年5-1]
- We report here homologous recombination (HR)-mediated gene targeting of two different genes in human PS cells (hiPSCs) and human ES cells (hESCs). HR-mediated correction of a chromosomally integrated mutant GFP reporter ...
- Induced Pluripotent Stem Cells and Embryonic Stem Cells Are Distinguished by Gene Expression Signatures
[作者：Chin, MH; Mason, MJ; Xie, W; Volinia, S; Singer, M; Peterson, C; Ambartsumyan, G; Aimiuwu, O; Richter, L; Zhang, J; Khvorostov, I; Ott, V; Grunstein, M; Lavon, N; Benvenisty, N; Croce, CM; Clark, AT; Baxter, T; Pyle, AD; Teitell, MA; Pelegrini, M; Plath, K; Lowry, WE,期刊：Cell Stem Cell, 页码：111-123 , 文章类型： Article，,卷期：2009年5-1]
- Induced pluripotent stem cells (iPSCs) outwardly appear to be indistinguishable from embryonic stem cells (ESCs). A study of gene expression profiles of mouse and human ESCs and iPSCs suggests that, while iPSCs are quite...
- Metastable Pluripotent States in NOD-Mouse-Derived ESCs (vol 4, pg 513, 2009)
[作者：Hanna, J; Markoulaki, S; Mitalipova, M; Cheng, AW; Cassady, JP; Staerk, J; Carey, BW; Lengner, CJ; Foreman, R; Love, J; Gao, C; Kim, J; Jaenisch, R,期刊：Cell Stem Cell, 页码：124-124 , 文章类型： Correction，,卷期：2009年5-1]
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- SKP-ing TAp63: Stem Cell Depletion, Senescence, and Premature Aging
[作者：Beaudry, VG; Attardi, LD,期刊：Cell Stem Cell, 页码：1-2 , 文章类型： Editorial Material，,卷期：2009年5-1]
- The p53 family member p63 comprises multiple isoforms and is critical for stratified epithelial development. In this issue of Cell Stem Cell, by generating isoform-specific knockout mice, Su et al. (2009) reveal pivotal ...
- gPS Navigates Germ Cells to Pluripotency
[作者：Geijsen, N; Hochedlinger, K,期刊：Cell Stem Cell, 页码：3-4 , 文章类型： Editorial Material，,卷期：2009年5-1]
- The establishment of pluripotent stem cell lines from explanted testes has been hampered by a poor understanding of their cellular origin. In this issue of Cell Stem Cell, Ko et al. (2009) reproducibly generate pluripote...
- TEL Me ALL
[作者：Sloma, I; Eaves, CJ,期刊：Cell Stem Cell, 页码：5-6 , 文章类型： Editorial Material，,卷期：2009年5-1]
- Genetically engineered mouse models are powerful systems for dissecting the process of human leukemo-genesis. In this issue of Cell Stem Cell, Schindler et al. (2009) describe the elegant use of this approach to dissect,...
- Stem Cell Aging and Aberrant Differentiation within the Niche
[作者：Choi, J; Artandi, S,期刊：Cell Stem Cell, 页码：6-8 , 文章类型： Editorial Material，,卷期：2009年5-1]
- Stem cells age, but the underlying mechanisms remain unclear. In a recent issue of Cell, Inomata and colleagues (2009) show that DNA damage, a prime suspect in stem cell aging, causes graying and loss of melanocyte stem ...
- Sleuthing the Source of Regeneration by MSCs
[作者：Pittenger, M,期刊：Cell Stem Cell, 页码：8-10 , 文章类型： Editorial Material，,卷期：2009年5-1]
- Mesenchymal stem cells (MSCs) can differentiate into useful cell types and also have the ability to modulate inflammation. In this issue of Cell Stem Cell, Lee et al. (2009) investigate the production of the soluble infl...
- Pluripotent Stem Cell-Derived Gametes: Truth and (Potential) Consequences
[作者：Mathews, DJH; Donovan, PJ; Harris, J; Lovell-Badge, R; Savulescu, J; Faden, R,期刊：Cell Stem Cell, 页码：11-14 , 文章类型： Article，,卷期：2009年5-1]
- An emerging body of data suggests that pluripotent stem cells may be able to differentiate to form eggs and sperm. We discuss the state of the science and the potential social implications and offer recommendations for a...
- Control of Stem Cell Fate by Physical Interactions with the Extracellular Matrix
[作者：Guilak, F; Cohen, DM; Estes, BT; Gimble, JM; Liedtke, W; Chen, CS,期刊：Cell Stem Cell, 页码：17-26 , 文章类型： Review，,卷期：2009年5-1]
- A diverse array of environmental factors contributes to the overall control of stem cell activity. In particular, new data continue to mount on the influence of the extracellular matrix (ECM) on stem cell fate through ph...
- TAp63 Prevents Premature Aging by Promoting Adult Stem Cell Maintenance
[作者：Su, XH; Paris, M; Gi, YJ; Tsai, KY; Cho, MS; Lin, YL; Biernaskie, JA; Sinha, S; Prives, C; Pevny, LH; Miller, FD; Flores, ER,期刊：Cell Stem Cell, 页码：64-75 , 文章类型： Article，,卷期：2009年5-1]
- The cellular mechanisms that regulate the maintenance of adult tissue stem cells are still largely unknown. We show here that the p53 family member, TAp63, is essential for maintenance of epidermal and dermal precursors ...
- Genetic Reconstruction of Mouse Spermatogonial Stem Cell Self-Renewal In Vitro by Ras-Cyclin D2 Activation
[作者：Lee, J; Kanatsu-Shinohara, M; Morimoto, H; Kazuki, Y; Takashima, S; Oshimura, M; Toyokuni, S; Shinohara, T,期刊：Cell Stem Cell, 页码：76-86 , 文章类型： Article，,卷期：2009年5-1]
- Spermatogonial stem cells (SSCs) undergo self-renewal division and support spermatogenesis. Although several cytokines coordinate to drive SSC self-renewal, little is known about the mechanisms underlying this process. W...
- Induction of Pluripotency in Adult Unipotent Germline Stem Cells
[作者：Ko, K; Tapia, N; Wu, GM; Kim, JB; Arauzo-Bravo, MJ; Sasse, P; Glaser, T; Ruau, D; Han, DW; Greber, B; Hausdorfer, K; Sebastiano, V; Stehling, M; Fleischmann, BK; Brustle, O; Zenke, M; Scholer, HR,期刊：Cell Stem Cell, 页码：87-96 , 文章类型： Article，,卷期：2009年5-1]
- Mouse and human stem cells with features similar to those of embryonic stem cells have been derived from testicular cells. Although pluripotent stem cells have been obtained from defined germline stem cells (GSCs) of mou...
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