- Duchenne Muscular Dystrophy Models Show Their Age
[作者：Chamberlain, JS,期刊：Cell, 页码：1040-1042 , 文章类型： Editorial Material，,卷期：2010年143-7]
- The lack of appropriate animal models has hampered efforts to develop therapies for Duchenne muscular dystrophy (DMD). A new mouse model lacking both dystrophin and telomerase (Sacco et al., 2010) closely mimics the path...
- New Ways to Make Old Walls: Bacterial Surprises
[作者：Young, KD,期刊：Cell, 页码：1042-1044 , 文章类型： Editorial Material，,卷期：2010年143-7]
- Two papers in this issue of Cell (Paradis-Bleau et al., 2010 and Typas et al., 2010) report that the lipoproteins LpoA and LpoB are required for the synthesis of cell walls in Escherichia coli. Attached to the bacterial ...
- Wnt Signaling: Multivesicular Bodies Hold GSK3 Captive
[作者：Niehrs, C; Acebron, SP,期刊：Cell, 页码：1044-1046 , 文章类型： Editorial Material，,卷期：2010年143-7]
- Two key events in Wnt signal transduction, receptor endocytosis and inactivation of Glycogen Synthase Kinase 3 (GSK3), remain incompletely understood. Taelman et al. (2010) discover that Wnt signaling inactivates GSK3 by...
- Breaking the Diffraction Barrier: Super-Resolution Imaging of Cells
[作者：Bo, HA; Babcock, H; Xiaowei, ZA,期刊：Cell, 页码：1047-1058 , 文章类型： Article，,卷期：2010年143-7]
- Anyone who has used a light microscope has wished that its resolution could be a little better. Now, after centuries of gradual improvements, fluorescence microscopy has made a quantum leap in its resolving power due, in...
- Short Telomeres and Stem Cell Exhaustion Model Duchenne Muscular Dystrophy in mdx/mTR Mice
[作者：Sacco, A; Mourkioti, F; Tran, R; Choi, J; Llewellyn, M; Kraft, P; Shkreli, M; Delp, S; Pomerantz, JH; Artandi, SE; Blau, HM,期刊：Cell, 页码：1059-1071 , 文章类型： Article，,卷期：2010年143-7]
- In Duchenne muscular dystrophy (DMD), dystrophin mutation leads to progressive lethal skeletal muscle degeneration. For unknown reasons, dystrophin deficiency does not recapitulate DMD in mice (mdx), which have mild skel...
- C/EBP beta Controls Exercise-Induced Cardiac Growth and Protects against Pathological Cardiac Remodeling
[作者：Bostrom, P; Mann, N; Wu, J; Quintero, PA; Plovie, ER; Panakova, D; Gupta, RK; Xiao, CY; MacRae, CA; Rosenzweig, A; Spiegelman, BM,期刊：Cell, 页码：1072-1083 , 文章类型： Article，,卷期：2010年143-7]
- The heart has the ability to growin size in response to exercise, but little is known about the transcriptional mechanisms underlying physiological hypertrophy. Adult cardiomyocytes have also recently been proven to hold...
- Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals
[作者：Carone, BR; Fauquier, L; Habib, N; Shea, JM; Hart, CE; Li, RW; Bock, C; Li, CJ; Gu, HC; Zamore, PD; Meissner, A; Weng, ZP; Hofmann, HA; Friedman, N; Rando, OJ,期刊：Cell, 页码：1084-1096 , 文章类型： Article，,卷期：2010年143-7]
- Epigenetic information can be inherited through the mammalian germline and represents a plausible transgenerational carrier of environmental information. To test whether transgenerational inheritance of environmental inf...
- Regulation of Peptidoglycan Synthesis by Outer-Membrane Proteins
[作者：Typas, A; Banzhaf, M; van Saparoea, BV; Verheul, J; Biboy, J; Nichols, RJ; Zietek, M; Beilharz, K; Kannenberg, K; von Rechenberg, M; Breukink, E; den Blaauwen, T; Gross, CA; Vollmer, W,期刊：Cell, 页码：1097-1109 , 文章类型： Article，,卷期：2010年143-7]
- Growth of the mesh-like peptidoglycan (PG) sacculus located between the bacterial inner and outer membranes (OM) is tightly regulated to ensure cellular integrity, maintain cell shape, and orchestrate division. Cytoskele...
- Lipoprotein Cofactors Located in the Outer Membrane Activate Bacterial Cell Wall Polymerases
[作者：Paradis-Bleau, C; Markovski, M; Uehara, T; Lupoli, TJ; Walker, S; Kahne, DE; Bernhardt, TG,期刊：Cell, 页码：1110-1120 , 文章类型： Article，,卷期：2010年143-7]
- Most bacteria surround themselves with a peptidoglycan (PG) exoskeleton synthesized by polysaccharide polymerases called penicillin-binding proteins (PBPs). Because they are the targets of penicillin and related antibiot...
- Wnt Signaling Requires Sequestration of Glycogen Synthase Kinase 3 inside Multivesicular Endosomes
[作者：Taelman, VF; Dobrowolski, R; Plouhinec, JL; Fuentealba, LC; Vorwald, PP; Gumper, I; Sabatini, DD; De Robertis, EM,期刊：Cell, 页码：1136-1148 , 文章类型： Article，,卷期：2010年143-7]
- Canonical Wnt signaling requires inhibition of Glycogen Synthase Kinase 3 (GSK3) activity, but the molecular mechanism by which this is achieved remains unclear. Here, we report that Wnt signaling triggers the sequestrat...
- Meningococcus Hijacks a beta 2-Adrenoceptor/beta-Arrestin Pathway to Cross Brain Microvasculature Endothelium
[作者：Coureuil, M; Lecuyer, H; Scott, MGH; Boularan, C; Enslen, H; Soyer, M; Mikaty, G; Bourdoulous, S; Nassif, X; Marullo, S,期刊：Cell, 页码：1149-1160 , 文章类型： Article，,卷期：2010年143-7]
- Following pilus-mediated adhesion to human brain endothelial cells, meningococcus (N. meningitidis), the bacterium causing cerebrospinal meningitis, initiates signaling cascades, which eventually result in the opening of...
- A Tissue-Specific Atlas of Mouse Protein Phosphorylation and Expression
[作者：Huttlin, EL; Jedrychowski, MP; Elias, JE; Goswami, T; Rad, R; Beausoleil, SA; Villen, J; Haas, W; Sowa, ME; Gygi, SP,期刊：Cell, 页码：1174-1189 , 文章类型： Article，,卷期：2010年143-7]
- Although most tissues in an organism are genetically identical, the biochemistry of each is optimized to fulfill its unique physiological roles, with important consequences for human health and disease. Each tissue's uni...
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