- Novel Alkynylphosphonate Analogue of Calcitriol with Potent Antiproliferative Effects in Cancer Cells and Lack of Calcemic Activity
[作者:SALOMON DEBORA G; GRIOLI SILVINA M; BUSCHIAZZO MAXIMILIANO; MASCARO EVANGELINA; VITALE CRISTIAN; RADIVOY GABRIEL; PEREZ MANUEL; FALL YAGAMARE; MESRI ENRIQUE A; CURINO ALEJANDRO C; FACCHINETTI MARIA M,期刊:ACS Medicinal Chemistry Letters, 页码:503-508 , 文章类型: Article,,卷期:2011年2-7]
- Here, we describe the design and synthesis of diethyl [(5Z,7E)-(1S,3R)-1,3-dihydroxy-9,10-secochola-5,7,10(19)-trien-23-in-24- yl] phosphonate (compound 10), which combines the low calcemic properties of phosphonates wit...
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