- Cilia, adenomatous polyposis coli and associated diseases
[作者：Li, Z; Li, W; Song, L; Zhu, W,期刊：Oncogene, 页码：1475-1483 , 文章类型： Review，,卷期：2012年31-12]
- Cilium is a conservative cell organelle, found in many types of cell surfaces. Cilia are tail-like prominence protruding out of the cell surface, capable of locomotion and acting as the cell's signal transduction sensory...
- PP2A-B56 alpha controls oncogene-induced senescence in normal and tumor human melanocytic cells
[作者：Mannava, S; Omilian, AR; Wawrzyniak, JA; Fink, EE; Zhuang, D; Miecznikowski, JC; Marshall, JR; Soengas, MS; Sears, RC; Morrison, CD; Nikiforov, MA,期刊：Oncogene, 页码：1484-1492 , 文章类型： Article，,卷期：2012年31-12]
- Oncoprotein C-MYC is overexpressed in human metastatic melanomas and melanoma-derived cells where it is required for the suppression of oncogene-induced senescence (OIS). The genetic events that maintain high levels of C...
- Fra-1 controls motility of bladder cancer cells via transcriptional upregulation of the receptor tyrosine kinase AXL
[作者：Sayan, AE; Stanford, R; Vickery, R; Grigorenko, E; Diesch, J; Kulbicki, K; Edwards, R; Pal, R; Greaves, P; Jariel-Encontre, I; Piechaczyk, M; Kriajevska, M; Mellon, JK; Dhillon, AS; Tulchinsky, E,期刊：Oncogene, 页码：1493-1503 , 文章类型： Article，,卷期：2012年31-12]
- Fos-related antigen 1 (Fra-1) is a Fos family member overexpressed in several types of human cancers. Here, we report that Fra-1 is highly expressed in the muscle-invasive form of the carcinoma of the bladder (80%) and t...
- Either Kras activation or Pten loss similarly enhance the dominant-stable CTNNB1-induced genetic program to promote granulosa cell tumor development in the ovary and testis
[作者：Richards, JS; Fan, HY; Liu, Z; Tsoi, M; Lague, MN; Boyer, A; Boerboom, D,期刊：Oncogene, 页码：1504-1520 , 文章类型： Article，,卷期：2012年31-12]
- WNT, RAS or phosphoinositide 3-kinase signaling pathways control specific stages of ovarian follicular development. To analyze the functional interactions of these pathways in granulosa cells during follicular developmen...
- MFG-E8/lactadherin regulates cyclins D1/D3 expression and enhances the tumorigenic potential of mammary epithelial cells
[作者：Carrascosa, C; Obula, RG; Missiaglia, E; Lehr, HA; Delorenzi, M; Frattini, M; Ruegg, C; Mariotti, A,期刊：Oncogene, 页码：1521-1532 , 文章类型： Article，,卷期：2012年31-12]
- Milk fat globule-EGF factor 8 (MFG-E8) is a glycoprotein highly expressed in breast cancer that contributes to tumor progression through largely undefined mechanisms. By analyzing publicly available gene expression profi...
- Correlation analysis of p53 protein isoforms with NPM1/FLT3 mutations and therapy response in acute myeloid leukemia
[作者：Anensen, N; Hjelle, SM; Van Belle, W; Haaland, I; Silden, E; Bourdon, JC; Hovland, R; Tasken, K; Knappskog, S; Lonning, PE; Bruserud, O; Gjertsen, BT,期刊：Oncogene, 页码：1533-1545 , 文章类型： Article，,卷期：2012年31-12]
- The wild-type tumor-suppressor gene TP53 encodes several isoforms of the p53 protein. However, while the role of p53 in controlling normal cell cycle progression and tumor suppression is well established, the clinical si...
- Deacetylation of FOXO3 by SIRT1 or SIRT2 leads to Skp2-mediated FOXO3 ubiquitination and degradation
[作者：Wang, F; Chan, CH; Chen, K; Guan, X; Lin, HK; Tong, Q,期刊：Oncogene, 页码：1546-1557 , 文章类型： Article，,卷期：2012年31-12]
- Sirtuin deacetylases and FOXO (Forkhead box, class O) transcription factors have important roles in many biological pathways, including cancer development. SIRT1 and SIRT2 deacetylate FOXO factors to regulate FOXO functi...
- A novel oncogenic role for the miRNA-506-514 cluster in initiating melanocyte transformation and promoting melanoma growth
[作者：Streicher, KL; Zhu, W; Lehmann, KP; Georgantas, RW; Morehouse, CA; Brohawn, P; Carrasco, RA; Xiao, Z; Tice, DA; Higgs, BW; Richman, L; Jallal, B; Ranade, K; Yao, Y,期刊：Oncogene, 页码：1558-1570 , 文章类型： Article，,卷期：2012年31-12]
- Malignant melanoma is the most aggressive form of skin cancer and its incidence has doubled in the last two decades. It represents only 4% of skin cancer cases per year, but causes as many as 74% of skin cancer deaths. E...
- Oncogenic activation of FOXR1 by 11q23 intrachromosomal deletion-fusions in neuroblastoma
[作者：Santo, EE; Ebus, ME; Koster, J; Schulte, JH; Lakeman, A; van Sluis, P; Vermeulen, J; Gisselsson, D; Ora, I; Lindner, S; Buckley, PG; Stallings, RL; Vandesompele, J; Eggert, A; Caron, HN; Versteeg, R; Molenaar, JJ,期刊：Oncogene, 页码：1571-1581 , 文章类型： Article，,卷期：2012年31-12]
- Neuroblastoma tumors frequently show loss of heterozygosity of chromosome 11q with a shortest region of overlap in the 11q23 region. These deletions are thought to cause inactivation of tumor suppressor genes leading to ...
- Molecular chaperone complexes with antagonizing activities regulate stability and activity of the tumor suppressor LKB1
[作者：Gaude, H; Aznar, N; Delay, A; Bres, A; Buchet-Poyau, K; Caillat, C; Vigouroux, A; Rogon, C; Woods, A; Vanacker, JM; Hohfeld, J; Perret, C; Meyer, P; Billaud, M; Forcet, C,期刊：Oncogene, 页码：1582-1591 , 文章类型： Article，,卷期：2012年31-12]
- LKB1 is a tumor suppressor that is constitutionally mutated in a cancer-prone condition, called Peutz-Jeghers syndrome, as well as somatically inactivated in a sizeable fraction of lung and cervical neoplasms. The LKB1 g...
- Cellular features of senescence during the evolution of human and murine ductal pancreatic cancer
[作者：Caldwell, ME; DeNicola, GM; Martins, CP; Jacobetz, MA; Maitra, A; Hruban, RH; Tuveson, DA,期刊：Oncogene, 页码：1599-1608 , 文章类型： Article，,卷期：2012年31-12]
- During tumor initiation, oncogene-induced senescence (OIS) is proposed to limit the progression of preneoplasms to invasive carcinoma unless circumvented by the acquisition of certain tumor suppressor mutations. Using a ...
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