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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共92条记录   Chance and Serendipity in Science: Two Examples from My Own Career [作者：Steinberg, D,期刊：Journal of Biological Chemistry, 页码：37895-37904 , 文章类型： Article，,卷期：2011年286-44] The usual scientific paper follows a rather narrowly (but not ever rigidly) defined pattern. Both the author and the journal like to see a linear logical presentation of a "story." Seldom does the paper give the reader t... Reporter Mutation Studies Show That Nicotinic Acetylcholine Receptor (nAChR) alpha 5 Subunits and/or Variants Modulate Function of alpha 6*-nAChR* [作者：Dash, B; Chang, YC; Lukas, RJ,期刊：Journal of Biological Chemistry, 页码：37905-37918 , 文章类型： Article，,卷期：2011年286-44] To further the understanding of functional alpha 6 alpha 5*-nicotinic acetylcholine receptors (nAChR; the asterisk (*) indicates known or possible presence of other subunits), we have heterologously expressed in oocytes ... Ca(2+) Influx through Reverse Mode Na(+)/Ca(2+) Exchange Is Critical for Vascular Endothelial Growth Factor-mediated Extracellular Signal-regulated Kinase (ERK) 1/2 Activation and Angiogenic Functions of Human Endothelial Cells [作者：Andrikopoulos, P; Baba, A; Matsuda, T; Djamgoz, MBA; Yaqoob, MM; Eccles, SA,期刊：Journal of Biological Chemistry, 页码：37919-37931 , 文章类型： Article，,卷期：2011年286-44] VEGF is a key angiogenic cytokine and a major target in antiangiogenic therapeutic strategies. In endothelial cells (ECs), VEGF binds VEGF receptors and activates ERK1/2 through the phospholipase gamma (PLC gamma)-PKC al... Paxillin Enables Attachment-independent Tyrosine Phosphorylation of Focal Adhesion Kinase and Transformation by RAS [作者：Wade, R; Brimer, N; Lyons, C; Vande Pol, S,期刊：Journal of Biological Chemistry, 页码：37932-37944 , 文章类型： Article，,卷期：2011年286-44] Paxillin and HIC5 are closely related adapter proteins that regulate cell migration and are tyrosine-phosphorylated by focal adhesion kinase (FAK). Paxillin, HIC5, and FAK tyrosine phosphorylation increase upon cell atta... Premature Activation of the Paramyxovirus Fusion Protein before Target Cell Attachment with Corruption of the Viral Fusion Machinery [作者：Farzan, SF; Palermo, LM; Yokoyama, CC; Orefice, G; Fornabaio, M; Sarkar, A; Kellogg, GE; Greengard, O; Porotto, M; Moscona, A,期刊：Journal of Biological Chemistry, 页码：37945-37954 , 文章类型： Article，,卷期：2011年286-44] Paramyxoviruses, including the childhood pathogen human parainfluenza virus type 3, enter host cells by fusion of the viral and target cell membranes. This fusion results from the concerted action of its two envelope gly... Amyloid-beta-induced Synapse Damage Is Mediated via Cross-linkage of Cellular Prion Proteins [作者：Bate, C; Williams, A,期刊：Journal of Biological Chemistry, 页码：37955-37963 , 文章类型： Article，,卷期：2011年286-44] The cellular prion protein (PrP(C)), which is highly expressed at synapses, was identified as a receptor for the amyloid-beta (A beta) oligomers that are associated with dementia in Alzheimer disease. Here, we report tha... Induction of Lectin-like Transcript 1 (LLT1) Protein Cell Surface Expression by Pathogens and Interferon-gamma Contributes to Modulate Immune Responses [作者：Germain, C; Meier, A; Jensen, T; Knapnougel, P; Poupon, G; Lazzari, A; Neisig, A; Hakansson, K; Dong, T; Wagtmann, N; Galsgaard, ED; Spee, P; Braud, VM,期刊：Journal of Biological Chemistry, 页码：37964-37975 , 文章类型： Article，,卷期：2011年286-44] CD161 is a C-type lectin-like receptor expressed on human natural killer (NK) cells and subsets of T cells. CD161 has been described as an inhibitory receptor that regulates NK cell-mediated cytotoxicity and IFN-gamma pr... Trefoil Factor 2 Requires Na/H Exchanger 2 Activity to Enhance Mouse Gastric Epithelial Repair [作者：Xue, L; Aihara, E; Wang, TC; Montrose, MH,期刊：Journal of Biological Chemistry, 页码：38375-38382 , 文章类型： Article，,卷期：2011年286-44] Trefoil factor (TFF) peptides are pivotal for gastric restitution after surface epithelial damage, but TFF cellular targets that promote cell migration are poorly understood. Conversely, Na/H exchangers (NHE) are often i... The Ca(2+)-ATPase (SERCA1) Is Inhibited by 4-Aminoquinoline Derivatives through Interference with Catalytic Activation by Ca(2+), Whereas the ATPase E(2) State Remains Functional [作者：Bartolommei, G; Tadini-Buoninsegni, F; Moncelli, MR; Gemma, S; Camodeca, C; Butini, S; Campiani, G; Lewis, D; Inesi, G,期刊：Journal of Biological Chemistry, 页码：38383-38389 , 文章类型： Article，,卷期：2011年286-44] Several clotrimazole (CLT) and 4-aminoquinoline derivatives were synthesized and found to exhibit in vitro antiplasmodial activity with IC(50) ranging from nM to mu M values. We report here that some of these compounds p... Polar Transmembrane-based Amino Acids in Presenilin 1 Are Involved in Endoplasmic Reticulum Localization, Pen2 Protein Binding, and gamma-Secretase Complex Stabilization [作者：Fassler, M; Li, XL; Kaether, C,期刊：Journal of Biological Chemistry, 页码：38390-38396 , 文章类型： Article，,卷期：2011年286-44] gamma-Secretase is composed of the four membrane proteins presenilin, nicastrin, Pen2, and Aph1. These four proteins assemble in a coordinated and regulated manner into a high molecular weight complex. The subunits const... Homeostasis of Extracellular ATP in Human Erythrocytes [作者：Montalbetti, N; Denis, MFL; Pignataro, OP; Kobatake, E; Lazarowski, ER; Schwarzbaum, PJ,期刊：Journal of Biological Chemistry, 页码：38397-38407 , 文章类型： Article，,卷期：2011年286-44] We explored the intra- and extracellular processes governing the kinetics of extracellular ATP (ATPe) in human erythrocytes stimulated with agents that increase cAMP. Using the luciferin-luciferase reaction in off-line l... Chemical Kinetic Analysis of Thermal Decay of Rhodopsin Reveals Unusual Energetics of Thermal Isomerization and Hydrolysis of Schiff Base [作者：Liu, J; Liu, MY; Fu, L; Zhu, GA; Yan, ECY,期刊：Journal of Biological Chemistry, 页码：38408-38416 , 文章类型： Article，,卷期：2011年286-44] The thermal properties of rhodopsin, which set the threshold of our vision, have long been investigated, but the chemical kinetics of the thermal decay of rhodopsin has not been revealed in detail. To understand thermal ... Identification of a Novel Gene, Anorexia, Regulating Feeding Activity via Insulin Signaling in Drosophila melanogaster [作者：Ryuda, M; Tsuzuki, S; Matsumoto, H; Oda, Y; Tanimura, T; Hayakawa, Y,期刊：Journal of Biological Chemistry, 页码：38417-38426 , 文章类型： Article，,卷期：2011年286-44] Feeding activities of animals, including insects, are influenced by various signals from the external environment, internal energy status, and physiological conditions. Full understanding of how such signals are integrat... Expanded CUG Repeats Dysregulate RNA Splicing by Altering the Stoichiometry of the Muscleblind 1 Complex [作者：Paul, S; Dansithong, W; Jog, SP; Holt, I; Mittal, S; Brook, JD; Morris, GE; Comai, L; Reddy, S,期刊：Journal of Biological Chemistry, 页码：38427-38438 , 文章类型： Article，,卷期：2011年286-44] To understand the role of the splice regulator muscleblind 1 (MBNL1) in the development of RNA splice defects in myotonic dystrophy I (DM1), we purified RNA-independent MBNL1 complexes from normal human myoblasts and exa... Structural Basis for Hemoglobin Capture by Staphylococcus aureus Cell-surface Protein, IsdH [作者：Kumar, KK; Jacques, DA; Pishchany, G; Caradoc-Davies, T; Spirig, T; Malmirchegini, GR; Langley, DB; Dickson, CF; Mackay, JP; Clubb, RT; Skaar, EP; Guss, JM; Gell, DA,期刊：Journal of Biological Chemistry, 页码：38439-38447 , 文章类型： Article，,卷期：2011年286-44] Pathogens must steal iron from their hosts to establish infection. In mammals, hemoglobin (Hb) represents the largest reservoir of iron, and pathogens express Hb-binding proteins to access this source. Here, we show how ... Enteric Commensal Bacteria Induce Extracellular Signal-regulated Kinase Pathway Signaling via Formyl Peptide Receptor-dependent Redox Modulation of Dual Specific Phosphatase 3 [作者：Wentworth, CC; Alam, A; Jones, RM; Nusrat, A; Neish, AS,期刊：Journal of Biological Chemistry, 页码：38448-38455 , 文章类型： Article，,卷期：2011年286-44] The normal microbial occupants of the mammalian intestine are crucial for maintaining gut homeostasis, yet the mechanisms by which intestinal cells perceive and respond to the microbiota are largely unknown. Intestinal e...