- Role of Cytochrome P450 Polymorphisms in the Development of Pulmonary Drug Toxicity A Case-Control Study in the Netherlands
[作者:Wijnen, PAHM; Drent, M; Nelemans, PJ; Kuijpers, PMJC; Koek, GH; Neef, C; Haenen, GRMM; Bekers, O,期刊:Drug safety, 页码:1125-1134 , 文章类型: Article,,卷期:2008年31-12]
- Background: Drug-induced pulmonary toxicity is a serious and expanding problem with often unknown aetiology. Many drugs are metabolized by cytochrome P450 (CYP) enzymes. Objective: To establish whether allelic variation ...
- Statin-Associated Psychiatric Adverse Events A Case/Non-Case Evaluation of an Italian Database of Spontaneous Adverse Drug Reaction Reporting
[作者:Tuccori, M; Lapi, F; Testi, A; Coli, D; Moretti, U; Vannacci, A; Motola, D; Salvo, F; Rivolta, AL; Blandizzi, C; Mugelli, A; Del Tacca, M,期刊:Drug safety, 页码:1115-1123 , 文章类型: Article,,卷期:2008年31-12]
- Background: The inhibitors of HMG-CoA reductase ('statins') are widely prescribed hypolipidaemic drugs, which have been evaluated in several clinical trials involving hundreds of thousands of patients. From a safety pers...
- Long-Term Consequences of Drugs on the Paediatric Cardiovascular System
[作者:Hausner, E; Fiszman, ML; Hanig, J; Harlow, P; Zornberg, G; Sobel, S,期刊:Drug safety, 页码:1083-1096 , 文章类型: Review,,卷期:2008年31-12]
- Many pharmacological and toxicological actions of drugs in children cannot be fully predicted from adult clinical experience or from standard non-clinical toxicology studies. Numerous drugs have direct or indirect pharma...
- Assessment of Neuropsychiatric Adverse Events in Influenza Patients Treated with Oseltamivir A Comprehensive Review
[作者:Toovey, S; Rayner, C; Prinssen, E; Chu, T; Donner, B; Thakrar, B; Dutkowski, R; Hoffmann, G; Breidenbach, A; Lindemann, L; Carey, E; Boak, L; Gieschke, R; Sacks, S; Solsky, J; Small, I; Reddy, D,期刊:Drug safety, 页码:1097-1114 , 文章类型: Review,,卷期:2008年31-12]
- After reports from Japan of neuropsychiatric adverse events (NPAEs) in children taking oseltamivir phosphate (hereafter referred to as, oseltamivir [Tamiflu (R); F. Hoffmann-La Roche Ltd, Basel, Switzerland]) during and ...
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