- Enantioselective Preparation of P-Chiral Phosphine Oxides
[作者:ADAMS HARRY; COLLINS REBECCA C; JONES SIMON; WARNER CHRISTOPHER J A,期刊:Organic Letters, 页码:6576-6579 , 文章类型: Article,,卷期:2011年13-24]
- A highly efficient chiral auxiliary-based strategy for the asymmetric synthesis of P-chiral phosphine oxides in >98:2 er has been developed. The methodology involves the highly stereoselective formation of P-chiral oxazo...
- The Decarboxylative Strecker Reaction
[作者:DAS DEEPANKAR; RICHERS MATTHEW T; MA LONGLE; SEIDEL DANIEL,期刊:Organic Letters, 页码:6584-6587 , 文章类型: Article,,卷期:2011年13-24]
- alpha-Amino acids react with aldehydes in the presence of a cyanide source to form alpha-amino nitriles in what can be considered a decarboxylative variant of the classical Strecker reaction. This unprecedented transform...
- De Novo Asymmetric Synthesis of Fridamycin E
[作者:CHEN QIAN; MULZER MICHAEL; SHI PEI; BEUNING PENNY J; COATES GEOFFREY W; ODOHERTY GEORGE A,期刊:Organic Letters, 页码:6592-6595 , 文章类型: Article,,卷期:2011年13-24]
- A de novo asymmetric synthesis of (R)- and (S)-fridamycin E has been achieved. The entirely linear route required only nine steps from commercially available starting materials (16% overall yield). Key transformations in...
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