- Frequent p16-independent inactivation of p14(ARF) in human melanoma
[作者:Freedberg, DE; Rigas, SH; Russak, J; Gai, WM; Kaplow, M; Osman, I; Turner, F; Randerson-Moor, JA; Houghton, A; Busam, K; Bishop, DT; Bastian, BC; Newton-Bishop, JA; Polsky, D,期刊:Journal of the National Cancer Institute, 页码:784-795 , 文章类型: Article,,卷期:2008年100-11]
- Background The tumor suppressors p14(ARF) (ARF) and p16(INK4A) (p16) are encoded by overlapping reading frames at the CDKN2A/INK4A locus on chromosome 9p21. In human melanoma, the accumulated evidence has suggested that ...
- Serum vitamin D concentration and prostate cancer risk: A nested case-control study
[作者:Ahn, J; Peters, U; Albanes, D; Purdue, MP; Abnet, CC; Chatterjee, N; Horst, RL; Hollis, BW; Huang, WY; Shikany, JM; Hayes, RB,期刊:Journal of the National Cancer Institute, 页码:796-804 , 文章类型: Article,,卷期:2008年100-11]
- Background Epidemiological studies have yielded inconsistent associations between vitamin D status and prostate cancer risk, and few studies have evaluated whether the associations vary by disease aggressiveness. We inve...
- Randomized phase 3 trial of fluorouracil, epirubicin, and cyclophosphamide alone or followed by paclitaxel for early breast cancer
[作者:Martin, M; Rodriguez-Lescure, A; Ruiz, A; Alba, E; Calvo, L; Ruiz-Borrego, M; Munarriz, B; Rodriguez, CA; Crespo, C; de Alava, E; Garcia-Asenjo, JAL; Guitian, MD; Almenar, S; Gonzalez-Palacios, JF; Vera, F; Palacios, J; Ramos, M; Marco, JMG; Lluch, A; Alvarez, I; Segui, MA; Mayordomo, JI; Anton, A; Baena, JM; Plazaola, A; Modolell, A; Pelegri, A; Mel, JR; Aranda, E; Adrover, E; Alvarez, JV; Puche, JLG; Sanchez-Rovira, P; Gonzalez, S; Lopez-Vega, JM,期刊:Journal of the National Cancer Institute, 页码:805-814 , 文章类型: Article,,卷期:2008年100-11]
- Background Taxanes are among the most active drugs for the treatment of metastatic breast cancer, and, as a consequence, they have also been studied in the adjuvant setting.Methods After breast cancer surgery, women with...
- Estrogen-dependent signaling in a molecularly distinct subclass of aggressive prostate cancer
[作者:Setlur, SR; Mertz, KD; Hoshida, Y; Demichelis, F; Lupien, M; Perner, S; Sboner, A; Pawitan, Y; Andren, O; Johnson, LA; Tang, J; Adami, HO; Calza, S; Chinnaiyan, AM; Rhodes, D; Tomlins, S; Fall, K; Mucci, LA; Kantoff, PW; Stampfer, MJ; Andersson, SO; Varenhorst, E; Johansson, JE; Brown, M; Golub, TR; Rubin, MA,期刊:Journal of the National Cancer Institute, 页码:815-825 , 文章类型: Article,,卷期:2008年100-11]
- Background The majority of prostate cancers harbor gene fusions of the 5'-untranslated region of the androgen-regulated transmembrane protease serine 2 (TMPRSS2) promoter with erythroblast transformation-specific transcr...
- Should supplemental antioxidant administration be avoided during chemotherapy and radiation therapy?
[作者:Lawenda, BD; Kelly, KM; Ladas, EJ; Sagar, SM; Vickers, A; Blumberg, JB,期刊:Journal of the National Cancer Institute, 页码:773-783 , 文章类型: Editorial Material,,卷期:2008年100-11]
- Despite nearly two decades of research investigating the use of dietary antioxidant supplementation during conventional chemotherapy and radiation therapy, controversy remains about the efficacy and safety of this comple...
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