- THE ROLE OF NEUROTROPHINS AND MIMETICS IN THE TREATMENT OF OCULAR DISEASES
[作者:Bai, Y; Ge, J; Saragovi, HU; Zhuo, Y,期刊:Drugs of the Future, 页码:123-131 , 文章类型: Review,,卷期:2011年36-2]
- The optic nerve is a bundle of fibers and axons projecting from specialized retinal neurons, the retinal ganglion cells (RGCs), which make synaptic connections to the visual cortex. Glaucoma is a chronic and progressive ...
- ACIDIC MAMMALIAN CHITINASE (AMCASE): A NEW TARGET FOR OCULAR DISEASES
[作者:Musumeci, M; Bucolo, C; Drago, F; Musumeci, S,期刊:Drugs of the Future, 页码:141-148 , 文章类型: Article,,卷期:2011年36-2]
- Chitin, the second most abundant polysaccharide in nature, is not expressed in mammalian systems, but is found in the structural coatings of fungi, the exoskeleton of many arthropods and parasitic nematodes. The host def...
- CRIZOTINIB ALK/Met inhibitor Oncolytic
[作者:Nwizu, T; Kanteti, R; Kawada, I; Rolle, C; Vokes, EE; Salgia, R,期刊:Drugs of the Future, 页码:91-99 , 文章类型: Article,,卷期:2011年36-2]
- There are a number of molecular abnormalities that can occur in normal cells to induce a malignant phenotype. Recently, the tyrosine kinase receptor anaplastic lymphoma kinase (ALK) has been shown to have gain of functio...
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