- Combining radiation therapy with interstitial radiation-inducible TNF-alpha expression for locoregional cancer treatment
[作者:Jung, M; Dimtchev, A; Velena, A; Dritschilo, A,期刊:Cancer gene therapy, 页码:189-195 , 文章类型: Article,,卷期:2011年18-3]
- Brachytherapy (BRT) is used in the treatment of human cancers, including the cervix, breast, prostate and head and neck cancers. The primary advantage of BRT lies in the spatial conformation of the radiation deposition. ...
- In vitro and in vivo studies of adenovirus-mediated human norepinephrine transporter gene transduction to hepatocellular carcinoma
[作者:Jia, ZY; Deng, HF; Huang, R; Yang, YY; Yang, XC; Qi, ZZ; Ou, XH,期刊:Cancer gene therapy, 页码:196-205 , 文章类型: Article,,卷期:2011年18-3]
- The clinical value of I-131-MIBG for targeted imaging and targeted radiotherapy is limited to neural crest-derived tumors expressing human norepinephrine transporters (hNET) protein. To extend I-131-MIBG-targeted therapy...
- Dlxin-1, a member of MAGE family, inhibits cell proliferation, invasion and tumorigenicity of glioma stem cells
[作者:Reddy, EM; Chettiar, ST; Kaur, N; Ganeshkumar, R; Shepal, V; Shanbhag, NC; Shiras, A,期刊:Cancer gene therapy, 页码:206-218 , 文章类型: Article,,卷期:2011年18-3]
- We have previously reported the presence of Dlxin-1, a member of the melanoma antigen gene (MAGE) family, in the brain and showed its function as a cell cycle arrest protein, suggesting that Dlxin-1 may have anti-prolife...
- Inhibition of cervical cancer cell growth in vitro and in vivo with dual shRNAs
[作者:Gu, W; Payne, E; Sun, S; Burgess, M; McMillan, NAJ,期刊:Cancer gene therapy, 页码:219-227 , 文章类型: Article,,卷期:2011年18-3]
- RNA interference (RNAi)-based gene silencing is widely used in laboratories for gene function studies and also holds a great promise for developing treatments for diseases. However, in vivo delivery of RNAi therapy remai...
- A phase I dose-escalation clinical trial of intraoperative direct intratumoral injection of HF10 oncolytic virus in non-resectable patients with advanced pancreatic cancer
[作者:Nakao, A; Kasuya, H; Sahin, TT; Nomura, N; Kanzaki, A; Misawa, M; Shirota, T; Yamada, S; Fujii, T; Sugimoto, H; Shikano, T; Nomoto, S; Takeda, S; Kodera, Y; Nishiyama, Y,期刊:Cancer gene therapy, 页码:167-175 , 文章类型: Article,,卷期:2011年18-3]
- In 2005, we initiated a clinical trial that examined the efficacy of the oncolytic virus HF10 to treat pancreatic cancer. Pancreatic cancer continues to have a high mortality rate, despite multimodal treatments for patie...
- Enhanced antitumor activity by combining an adenovirus harboring ING4 with cisplatin for hepatocarcinoma cells
[作者:Xie, Y; Sheng, W; Miao, J; Xiang, J; Yang, J,期刊:Cancer gene therapy, 页码:176-188 , 文章类型: Article,,卷期:2011年18-3]
- The inhibitor of growth (ING) family proteins have been defined as candidate tumor suppressors. ING4 as a novel member of the ING family has potential tumor-suppressive effects. In this study, we explored the combined ef...
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