- Understanding wild-type and mutant p53 activities in human cancer: new landmarks on the way to targeted therapies
[作者:Goldstein, I; Marcel, V; Olivier, M; Oren, M; Rotter, V; Hainaut, P,期刊:Cancer gene therapy, 页码:2-11 , 文章类型: Review,,卷期:2011年18-1]
- Three decades of p53 research have led to many advances in understanding the basic biology of normal and cancer cells. Nonetheless, the detailed functions of p53 in normal cells, and even more so in cancer cells, remain ...
- Enhanced tumor therapy using vaccinia virus strain GLV-1h68 in combination with a beta-galactosidase-activatable prodrug seco-analog of duocarmycin SA
[作者:Seubert, CM; Stritzker, J; Hess, M; Donat, U; Sturm, JB; Chen, N; von Hof, JM; Krewer, B; Tietze, LF; Gentschev, I; Szalay, AA,期刊:Cancer gene therapy, 页码:42-52 , 文章类型: Article,,卷期:2011年18-1]
- Breast cancer is the most common cause of cancer-related death worldwide, thus remaining a crucial health problem among women despite advances in conventional therapy. Therefore, new alternative strategies are needed for...
- Multivalent immunity targeting tumor-associated antigens by intra-lymph node DNA-prime, peptide-boost vaccination
[作者:Smith, KA; Qiu, Z; Wong, R; Tam, VL; Tam, BL; Joea, DK; Quach, A; Liu, X; Pold, M; Malyankar, UM; Bot, A,期刊:Cancer gene therapy, 页码:63-76 , 文章类型: Article,,卷期:2011年18-1]
- Active immunotherapy of cancer has yet to yield effective therapies in the clinic. To evaluate the translatability of DNA-based vaccines we analyzed the profile of T-cell immunity by plasmid vaccination in a murine model...
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