- Notch signalling stabilises boundary formation at the midbrain-hindbrain organiser
[作者:Tossell, K; Kiecker, C; Wizenmann, A; Lang, E; Irving, C,期刊:Development, 页码:3745-3757 , 文章类型: Article,,卷期:2011年138-17]
- The midbrain-hindbrain interface gives rise to a boundary of particular importance in CNS development as it forms a local signalling centre, the proper functioning of which is essential for the formation of tectum and ce...
- Satellite cells, connective tissue fibroblasts and their interactions are crucial for muscle regeneration
[作者:Murphy, MM; Lawson, JA; Mathew, SJ; Hutcheson, DA; Kardon, G,期刊:Development, 页码:3625-3637 , 文章类型: Article,,卷期:2011年138-17]
- Muscle regeneration requires the coordinated interaction of multiple cell types. Satellite cells have been implicated as the primary stem cell responsible for regenerating muscle, yet the necessity of these cells for reg...
- Pax7-expressing satellite cells are indispensable for adult skeletal muscle regeneration
[作者:Sambasivan, R; Yao, R; Kissenpfennig, A; Van Wittenberghe, L; Paldi, A; Gayraud-Morel, B; Guenou, H; Malissen, B; Tajbakhsh, S; Galy, A,期刊:Development, 页码:3647-3656 , 文章类型: Article,,卷期:2011年138-17]
- Distinct cell populations with regenerative capacity have been reported to contribute to myofibres after skeletal muscle injury, including non-satellite cells as well as myogenic satellite cells. However, the relative co...
- Effective fiber hypertrophy in satellite cell-depleted skeletal muscle
[作者:McCarthy, JJ; Mula, J; Miyazaki, M; Erfani, R; Garrison, K; Farooqui, AB; Srikuea, R; Lawson, BA; Grimes, B; Keller, C; Van Zant, G; Campbell, KS; Esser, KA; Dupont-Versteegden, EE; Peterson, CA,期刊:Development, 页码:3657-3666 , 文章类型: Article,,卷期:2011年138-17]
- An important unresolved question in skeletal muscle plasticity is whether satellite cells are necessary for muscle fiber hypertrophy. To address this issue, a novel mouse strain (Pax7-DTA) was created which enabled the c...
- Ezh2 regulates anteroposterior axis specification and proximodistal axis elongation in the developing limb
[作者:Wyngaarden, LA; Delgado-Olguin, P; Su, IH; Bruneau, BG; Hopyan, S,期刊:Development, 页码:3759-3767 , 文章类型: Article,,卷期:2011年138-17]
- Specification and determination (commitment) of positional identities precedes overt pattern formation during development. In the limb bud, it is clear that the anteroposterior axis is specified at a very early stage and...
- Notch-mediated repression of bantam miRNA contributes to boundary formation in the Drosophila wing
[作者:Becam, I; Rafel, N; Hong, X; Cohen, SM; Milan, M,期刊:Development, 页码:3781-3789 , 文章类型: Article,,卷期:2011年138-17]
- Subdivision of proliferating tissues into adjacent compartments that do not mix plays a key role in animal development. The Actin cytoskeleton has recently been shown to mediate cell sorting at compartment boundaries, an...
- Kif7 promotes hedgehog signaling in growth plate chondrocytes by restricting the inhibitory function of Sufu
[作者:Hsu, SHC; Zhang, XY; Yu, CY; Li, ZJ; Wunder, JS; Hui, CC; Alman, BA,期刊:Development, 页码:3791-3801 , 文章类型: Article,,卷期:2011年138-17]
- Proper regulation of Indian hedgehog (Ihh) signaling is vital for chondrocyte proliferation and differentiation in the growth plate. Its dysregulation causes skeletal dysplasia, osteoarthritis or cartilaginous neoplasia....
- Differential adhesion and actomyosin cable collaborate to drive Echinoid-mediated cell sorting
[作者:Chang, LH; Chen, PL; Lien, MT; Ho, YH; Lin, CM; Pan, YT; Wei, SY; Hsu, JC,期刊:Development, 页码:3803-3812 , 文章类型: Article,,卷期:2011年138-17]
- Cell sorting involves the segregation of two cell populations into 'immiscible' adjacent tissues with smooth borders. Echinoid (Ed), a nectin ortholog, is an adherens junction protein in Drosophila, and cells mutant for ...
- Depletion of Kcnq1ot1 non-coding RNA does not affect imprinting maintenance in stem cells
[作者:Golding, MC; Magri, LS; Zhang, LY; Lalone, SA; Higgins, MJ; Mann, MRW,期刊:Development, 页码:3667-3678 , 文章类型: Article,,卷期:2011年138-17]
- To understand the complex regulation of genomic imprinting it is important to determine how early embryos establish imprinted gene expression across large chromosomal domains. Long non-coding RNAs (ncRNAs) have been asso...
- A LIM-homeobox gene is required for differentiation of Wnt-expressing cells at the posterior end of the planarian body
[作者:Hayashi, T; Motoishi, M; Yazawa, S; Itomi, K; Tanegashima, C; Nishimura, O; Agata, K; Tarui, H,期刊:Development, 页码:3679-3688 , 文章类型: Article,,卷期:2011年138-17]
- Planarians have high regenerative ability, which is dependent on pluripotent adult somatic stem cells called neoblasts. Recently, canonical Wnt/beta-catenin signaling was shown to be required for posterior specification,...
- A Sox10 enhancer element common to the otic placode and neural crest is activated by tissue-specific paralogs
[作者:Betancur, P; Sauka-Spengler, T; Bronner, M,期刊:Development, 页码:3689-3698 , 文章类型: Article,,卷期:2011年138-17]
- The otic placode, a specialized region of ectoderm, gives rise to components of the inner ear and shares many characteristics with the neural crest, including expression of the key transcription factor Sox10. Here, we sh...
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