- Lef1 is required for progenitor cell identity in the zebrafish lateral line primordium
[作者:McGraw, HF; Drerup, CM; Culbertson, MD; Linbo, T; Raible, DW; Nechiporuk, AV,期刊:Development, 页码:3921-3930 , 文章类型: Article,,卷期:2011年138-18]
- The zebrafish posterior lateral line (pLL) is a sensory system that comprises clusters of mechanosensory organs called neuromasts (NMs) that are stereotypically positioned along the surface of the trunk. The NMs are depo...
- Regulation of extra-embryonic endoderm stem cell differentiation by Nodal and Cripto signaling
[作者:Kruithof-de Julio, M; Alvarez, MJ; Galli, A; Chu, JH; Price, SM; Califano, A; Shen, MM,期刊:Development, 页码:3885-3895 , 文章类型: Article,,卷期:2011年138-18]
- The signaling pathway for Nodal, a ligand of the TGF beta superfamily, plays a central role in regulating the differentiation and/or maintenance of stem cell types that can be derived from the peri-implantation mouse emb...
- Differentiated skeletal cells contribute to blastema formation during zebrafish fin regeneration
[作者:Sousa, S; Afonso, N; Bensimon-Brito, A; Fonseca, M; Simoes, M; Leon, J; Roehl, H; Cancela, ML; Jacinto, A,期刊:Development, 页码:3897-3905 , 文章类型: Article,,卷期:2011年138-18]
- The origin of cells that generate the blastema following appendage amputation has been a long-standing question in epimorphic regeneration studies. The blastema is thought to originate from either stem (or progenitor) ce...
- Germ line differentiation factor Bag of Marbles is a regulator of hematopoietic progenitor maintenance during Drosophila hematopoiesis
[作者:Tokusumi, T; Tokusumi, Y; Hopkins, DW; Shoue, DA; Corona, L; Schulz, RA,期刊:Development, 页码:3879-3884 , 文章类型: Article,,卷期:2011年138-18]
- Bag of Marbles (Bam) is a stem cell differentiation factor in the Drosophila germ line. Here, we demonstrate that Bam has a crucial function in the lymph gland, the tissue that orchestrates the second phase of Drosophila...
- Hippo pathway regulation by cell morphology and stress fibers
[作者:Wada, KI; Itoga, K; Okano, T; Yonemura, S; Sasaki, H,期刊:Development, 页码:3907-3914 , 文章类型: Article,,卷期:2011年138-18]
- The Hippo signaling pathway plays an important role in regulation of cell proliferation. Cell density regulates the Hippo pathway in cultured cells; however, the mechanism by which cells detect density remains unclear. I...
- Lef1-dependent Wnt/beta-catenin signalling drives the proliferative engine that maintains tissue homeostasis during lateral line development
[作者:Valdivia, LE; Young, RM; Hawkins, TA; Stickney, HL; Cavodeassi, F; Schwarz, Q; Pullin, LM; Villegas, R; Moro, E; Argenton, F; Allende, ML; Wilson, SW,期刊:Development, 页码:3931-3941 , 文章类型: Article,,卷期:2011年138-18]
- During tissue morphogenesis and differentiation, cells must self-renew while contemporaneously generating daughters that contribute to the growing tissue. How tissues achieve this precise balance between proliferation an...
- Biological and mathematical modeling of melanocyte development
[作者:Luciani, F; Champeval, D; Herbette, A; Denat, L; Aylaj, B; Martinozzi, S; Ballotti, R; Kemler, R; Goding, CR; De Vuyst, F; Larue, L; Delmas, V,期刊:Development, 页码:3943-3954 , 文章类型: Article,,卷期:2011年138-18]
- We aim to evaluate environmental and genetic effects on the expansion/proliferation of committed single cells during embryonic development, using melanoblasts as a paradigm to model this phenomenon. Melanoblasts are a sp...
- Knockdown of embryonic myosin heavy chain reveals an essential role in the morphology and function of the developing heart
[作者:Rutland, CS; Polo-Parada, L; Ehler, E; Alibhai, A; Thorpe, A; Suren, S; Emes, RD; Patel, B; Loughna, S,期刊:Development, 页码:3955-3966 , 文章类型: Article,,卷期:2011年138-18]
- The expression and function of embryonic myosin heavy chain (eMYH) has not been investigated within the early developing heart. This is despite the knowledge that other structural proteins, such as alpha and beta myosin ...
- Otic ablation of smoothened reveals direct and indirect requirements for Hedgehog signaling in inner ear development
[作者:Brown, AS; Epstein, DJ,期刊:Development, 页码:3967-3976 , 文章类型: Article,,卷期:2011年138-18]
- In mouse embryos lacking sonic hedgehog (Shh), dorsoventral polarity within the otic vesicle is disrupted. Consequently, ventral otic derivatives, including the cochlear duct and saccule, fail to form, and dorsal otic de...
- The roles of maternal Vangl2 and aPKC in Xenopus oocyte and embryo patterning
[作者:Cha, SW; Tadjuidje, E; Wylie, C; Heasman, J,期刊:Development, 页码:3989-4000 , 文章类型: Article,,卷期:2011年138-18]
- The Xenopus oocyte contains components of both the planar cell polarity and apical-basal polarity pathways, but their roles are not known. Here, we examine the distribution, interactions and functions of the maternal pla...
- Loss of MAP3K1 enhances proliferation and apoptosis during retinal development
[作者:Mongan, M; Wang, JC; Liu, HS; Fan, YX; Jin, C; Kao, WYW; Xia, Y,期刊:Development, 页码:4001-4012 , 文章类型: Article,,卷期:2011年138-18]
- Precise coordination of progenitor cell proliferation and differentiation is essential for proper organ morphogenesis and function during mammalian development. The mitogen-activated protein kinase kinase kinase 1 ( MAP3...
- VAB-10 spectraplakin acts in cell and nuclear migration in Caenorhabditis elegans
[作者:Kim, HS; Murakami, R; Quintin, S; Mori, M; Ohkura, K; Tamai, KK; Labouesse, M; Sakamoto, H; Nishiwaki, K,期刊:Development, 页码:4013-4023 , 文章类型: Article,,卷期:2011年138-18]
- Cytoskeletal regulation is important in cell migration. The Caenorhabditis elegans gonadal distal tip cells (DTCs) offer a simple model with which to investigate the mechanism of cell migration in organogenesis. Here, we...
- Non-redundant function of dystroglycan and beta 1 integrins in radial sorting of axons
[作者:Berti, C; Bartesaghi, L; Ghidinelli, M; Zambroni, D; Figlia, G; Chen, ZL; Quattrini, A; Wrabetz, L; Feltri, ML,期刊:Development, 页码:4025-4037 , 文章类型: Article,,卷期:2011年138-18]
- Radial sorting allows the segregation of axons by a single Schwann cell (SC) and is a prerequisite for myelination during peripheral nerve development. Radial sorting is impaired in models of human diseases, congenital m...
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