- FatJ acts via the Hippo mediator Yap1 to restrict the size of neural progenitor cell pools
[作者:Van Hateren, NJ; Das, RM; Hautbergue, GM; Borycki, AG; Placzek, M; Wilson, SA,期刊:Development, 页码:1893-1902 , 文章类型: Article,,卷期:2011年138-10]
- The size, composition and functioning of the spinal cord is likely to depend on appropriate numbers of progenitor and differentiated cells of a particular class, but little is known about how cell numbers are controlled ...
- SHH propagates distal limb bud development by enhancing CYP26B1-mediated retinoic acid clearance via AER-FGF signalling
[作者:Probst, S; Kraemer, C; Demougin, P; Sheth, R; Martin, GR; Shiratori, H; Hamada, H; Iber, D; Zeller, R; Zuniga, A,期刊:Development, 页码:1913-1923 , 文章类型: Article,,卷期:2011年138-10]
- The essential roles of SHH in anteroposterior (AP) and AER-FGF signalling in proximodistal (PD) limb bud development are well understood. In addition, these morphoregulatory signals are key components of the self-regulat...
- Regulation of mammalian Notch signaling and embryonic development by the protein O-glucosyltransferase Rumi
[作者:Fernandez-Valdivia, R; Takeuchi, H; Samarghandi, A; Lopez, M; Leonardi, J; Haltiwanger, RS; Jafar-Nejad, H,期刊:Development, 页码:1925-1934 , 文章类型: Article,,卷期:2011年138-10]
- Protein O-glucosylation is a conserved post-translational modification that occurs on epidermal growth factor-like (EGF) repeats harboring the C-1-X-S-X-P-C-2 consensus sequence. The Drosophila protein O-glucosyltransfer...
- Neuron navigator 3a regulates liver organogenesis during zebrafish embryogenesis
[作者:Klein, C; Mikutta, J; Krueger, J; Scholz, K; Brinkmann, J; Liu, D; Veerkamp, J; Siegel, D; Abdelilah-Seyfried, S; le Noble, F,期刊:Development, 页码:1935-1945 , 文章类型: Article,,卷期:2011年138-10]
- Endodermal organogenesis requires a precise orchestration of cell fate specification and cell movements, collectively coordinating organ size and shape. In Caenorhabditis elegans, uncoordinated-53 (unc-53) encodes a neur...
- The enhancer of trithorax and polycomb gene Caf1/p55 is essential for cell survival and patterning in Drosophila development
[作者:Anderson, AE; Karandikar, UC; Pepple, KL; Chen, ZH; Bergmann, A; Mardon, G,期刊:Development, 页码:1957-1966 , 文章类型: Article,,卷期:2011年138-10]
- In vitro data suggest that the human RbAp46 and RbAp48 genes encode proteins involved in multiple chromatin remodeling complexes and are likely to play important roles in development and tumor suppression. However, to da...
- beta-Catenin is essential for Mullerian duct regression during male sexual differentiation
[作者:Kobayashi, A; Stewart, CA; Wang, Y; Fujioka, K; Thomas, NC; Jamin, SP; Behringer, RR,期刊:Development, 页码:1967-1975 , 文章类型: Article,,卷期:2011年138-10]
- During male sexual differentiation, the transforming growth factor-beta (TGF-beta) signaling molecule anti-Mullerian hormone (AMH; also known as Mullerian inhibiting substance, MIS) is secreted by the fetal testes and in...
- SMAD4-mediated WNT signaling controls the fate of cranial neural crest cells during tooth morphogenesis
[作者:Li, JY; Huang, XF; Xu, X; Mayo, J; Bringas, P; Jiang, RL; Wang, SL; Chai, Y,期刊:Development, 页码:1977-1989 , 文章类型: Article,,卷期:2011年138-10]
- TGF beta/BMP signaling regulates the fate of multipotential cranial neural crest (CNC) cells during tooth and jawbone formation as these cells differentiate into odontoblasts and osteoblasts, respectively. The functional...
- The phosphoinositide phosphatase MTM-1 regulates apoptotic cell corpse clearance through CED-5-CED-12 in C. elegans
[作者:Neukomm, LJ; Nicot, AS; Kinchen, JM; Almendinger, J; Pinto, SM; Zeng, S; Doukoumetzidis, K; Tronchere, H; Payrastre, B; Laporte, JF; Hengartner, MO,期刊:Development, 页码:2003-2014 , 文章类型: Article,,卷期:2011年138-10]
- Multicellular organisms use programmed cell death to eliminate unwanted or potentially harmful cells. Improper cell corpse removal can lead to autoimmune diseases. The development of interventional therapies that increas...
- Ret signalling integrates a craniofacial muscle module during development
[作者:Knight, RD; Mebus, K; d'Angelo, A; Yokoya, K; Heanue, T; Roehl, H,期刊:Development, 页码:2015-2024 , 文章类型: Article,,卷期:2011年138-10]
- An appropriate organisation of muscles is crucial for their function, yet it is not known how functionally related muscles are coordinated with each other during development. In this study, we show that the development o...
- MIM regulates vertebrate neural tube closure
[作者:Liu, W; Komiya, Y; Mezzacappa, C; Khadka, DK; Runnels, L; Habas, R,期刊:Development, 页码:2035-2047 , 文章类型: Article,,卷期:2011年138-10]
- Neural tube closure is a critical morphogenetic event that is regulated by dynamic changes in cell shape and behavior. Although previous studies have uncovered a central role for the non-canonical Wnt signaling pathway i...
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