- Effects of lentivirus-mediated HIF-1 alpha knockdown on hypoxia-related cisplatin resistance and their dependence on p53 status in fibrosarcoma cells
[作者:Hao, J; Song, X; Song, B; Liu, Y; Wei, L; Wang, X; Yu, J,期刊:Cancer gene therapy, 页码:449-455 , 文章类型: Article,,卷期:2008年15-7]
- Therapy targeting hypoxia-inducible factor-1 (HIF-1) to reverse the hypoxia-related drug resistance has received much interest. Despite a close interaction between HIF-1 and p53 and that p53 mutation is seen in > 50% of ...
- In vivo restoration of RhoB expression leads to ovarian tumor regression
[作者:Couderc, B; Pradines, A; Rafii, A; Golzio, M; Deviers, A; Allal, C; Berg, D; Penary, M; Teissie, J; Favre, G,期刊:Cancer gene therapy, 页码:456-464 , 文章类型: Article,,卷期:2008年15-7]
- Ovarian cancers are very aggressive cancers most often diagnosed when metastasis has already occurred in the entire peritoneal cavity. Ovarian adenocarcinoma cells present an undetectable level of RhoB GTPase. Using prec...
- Targeting sodium/iodide symporter gene expression for estrogen-regulated imaging and therapy in breast cancer
[作者:Montiel-Equihua, CA; Martin-Duque, P; de la Vieja, A; Quintanilla, M; Burnet, J; Vassaux, G; Lemoine, NR,期刊:Cancer gene therapy, 页码:465-473 , 文章类型: Article,,卷期:2008年15-7]
- Expression of the sodium iodide symporter (hNIS) has been detected in breast cancer tissue, but frequently, not at the levels necessary to mediate I-131 accumulation. Transducing the hNIS gene into breast cancer cells wi...
- Synergistic antitumor efficacy of suicide/ePNP gene and 6-methylpurine 2'-deoxyriboside via Salmonella against murine tumors
[作者:Fu, W; Lan, H; Li, S; Han, X; Gao, T; Ren, D,期刊:Cancer gene therapy, 页码:474-484 , 文章类型: Article,,卷期:2008年15-7]
- Some anaerobes and facultative anaerobes have been used in tumor-specific gene therapy by reason of their selective growth in tumors. In this work, we aimed to evaluate the anticancer efficacy of attenuated Salmonella ty...
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