- Time to Activate Lung Cancer Clinical Trials and Patient Enrollment: A Representative Comparison Study Between Two Academic Centers Across the Atlantic
[作者:Wang-Gillam, A; Williams, K; Novello, S; Gao, F; Scagliotti, GV; Govindan, R,期刊:Journal of clinical oncology, 页码:3803-3807 , 文章类型: Article,,卷期:2010年28-24]
- Purpose Activation of clinical trials is a lengthy process. We studied the procedures and time required to activate lung cancer clinical trials in a US academic center compared with a European center. Methods A retrospec...
- Chemoimmunotherapy With a Modified Hyper-CVAD and Rituximab Regimen Improves Outcome in De Novo Philadelphia Chromosome-Negative Precursor B-Lineage Acute Lymphoblastic Leukemia
[作者:Thomas, DA; O'Brien, S; Faderl, S; Garcia-Manero, G; Ferrajoli, A; Wierda, W; Ravandi, F; Verstovsek, S; Jorgensen, JL; Bueso-Ramos, C; Andreeff, M; Pierce, S; Garris, R; Keating, MJ; Cortes, J; Kantarjian, HM,期刊:Journal of clinical oncology, 页码:3880-3889 , 文章类型: Article,,卷期:2010年28-24]
- Purpose The adverse prognosis of CD20 expression in adults with de novo precursor B-lineage acute lymphoblastic leukemia (ALL) prompted incorporation of monoclonal antibody therapy with rituximab into the intensive chemo...
- Metastatic Apocrine Carcinoma of the Scalp: Prolonged Response to Systemic Chemotherapy
[作者:Tlemcani, K; Levine, D; Smith, RV; Brandwein-Gensler, M; Staffenberg, DA; Garg, MK; Shifteh, K; Haigentz, M,期刊:Journal of clinical oncology, 页码:E412-E414 , 文章类型: Article,,卷期:2010年28-24]
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- CNS Relapse in Acute Promyeloctyic Leukemia
[作者:Housman, E; Chang, P; Lane, SW; Blinder, R; Galinsky, I; Kesari, S; Ho, VT; Stone, RM; Mullally, A,期刊:Journal of clinical oncology, 页码:E409-E411 , 文章类型: Article,,卷期:2010年28-24]
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- Clinical, Molecular, and Prognostic Significance of WHO Type inv(3)(q21q26.2)/t(3;3)(q21;q26.2) and Various Other 3q Abnormalities in Acute Myeloid Leukemia
[作者:Lugthart, S; Groschel, S; Beverloo, HB; Kayser, S; Valk, PJM; van Zelderen-Bhola, SL; Ossenkoppele, GJ; Vellenga, E; van den Berg-de Ruiter, E; Schanz, U; Verhoef, G; Vandenberghe, P; Ferrant, A; Koohne, CH; Pfreundschuh, M; Horst, HA; Koller, E; von Lilienfeld-Toal, M; Bentz, M; Ganser, A; Schlegelberger, B; Jotterand, M; Krauter, J; Pabst, T; Theobald, M; Schlenk, RF; Delwel, R; Doohner, K; Lowenberg, B; Dohner, H,期刊:Journal of clinical oncology, 页码:3890-3898 , 文章类型: Article,,卷期:2010年28-24]
- Purpose Acute myeloid leukemia (AML) with inv(3)(q21q26.2)/t(3; 3)(q21; q26.2) inv(3)/t(3; 3)] is recognized as a distinctive entity in the WHO classification. Risk assignment and clinical and genetic characterization of...
- Absence of Biallelic TCR gamma Deletion Predicts Early Treatment Failure in Pediatric T-Cell Acute Lymphoblastic Leukemia
[作者:Gutierrez, A; Dahlberg, SE; Neuberg, DS; Zhang, JH; Grebliunaite, R; Sanda, T; Protopopov, A; Tosello, V; Kutok, J; Larson, RS; Borowitz, MJ; Loh, ML; Ferrando, AA; Winter, SS; Mullighan, CG; Silverman, LB; Chin, L; Hunger, SP; Sallan, SE; Look, AT,期刊:Journal of clinical oncology, 页码:3816-3823 , 文章类型: Article,,卷期:2010年28-24]
- Purpose To identify children with T-cell acute lymphoblastic leukemia (T-ALL) at high risk of induction chemotherapy failure by using DNA copy number analysis of leukemic cells collected at diagnosis. Patients and Method...
- Neoadjuvant Paclitaxel, Ifosfamide, and Cisplatin Chemotherapy for Metastatic Penile Cancer: A Phase II Study
[作者:Pagliaro, LC; Williams, DL; Daliani, D; Williams, MB; Osai, W; Kincaid, M; Wen, SJ; Thall, PF; Pettaway, CA,期刊:Journal of clinical oncology, 页码:3851-3857 , 文章类型: Article,,卷期:2010年28-24]
- Purpose Men with penile squamous cell carcinoma and regional lymph node involvement have a low probability of survival with lymphadenectomy alone. A multimodal approach to treatment is desirable for such patients. We per...
- Scale to Predict Survival After Surgery for Recurrent Glioblastoma Multiforme
[作者:Park, JK; Hodges, T; Arko, L; Shen, M; Dello Iacono, D; McNabb, A; Bailey, NO; Kreisl, TN; Iwamoto, FM; Sul, J; Auh, S; Park, GE; Fine, HA; Black, PM,期刊:Journal of clinical oncology, 页码:3838-3843 , 文章类型: Article,,卷期:2010年28-24]
- Purpose Despite initial treatment with surgical resection, radiotherapy, and chemotherapy, glioblastoma multiforme (GBM) virtually always recurs. Surgery is sometimes recommended to treat recurrence. In this study, we so...
- Next-Generation Sequencing Technology Reveals a Characteristic Pattern of Molecular Mutations in 72.8% of Chronic Myelomonocytic Leukemia by Detecting Frequent Alterations in TET2, CBL, RAS, and RUNX1
[作者:Kohlmann, A; Grossmann, V; Klein, HU; Schindela, S; Weiss, T; Kazak, B; Dicker, F; Schnittger, S; Dugas, M; Kern, W; Haferlach, C; Haferlach, T,期刊:Journal of clinical oncology, 页码:3858-3865 , 文章类型: Article,,卷期:2010年28-24]
- Purpose Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic malignancy that is characterized by features of both a myeloproliferative neoplasm and a myelodysplastic syndrome. Thus far, data on a comprehensiv...
- Single-Agent Arsenic Trioxide in the Treatment of Newly Diagnosed Acute Promyelocytic Leukemia: Long-Term Follow-Up Data
[作者:Mathews, V; George, B; Chendamarai, E; Lakshmi, KM; Desire, S; Balasubramanian, P; Viswabandya, A; Thirugnanam, R; Abraham, A; Shaji, RV; Srivastava, A; Chandy, M,期刊:Journal of clinical oncology, 页码:3866-3871 , 文章类型: Article,,卷期:2010年28-24]
- Purpose We previously reported our results with a single-agent arsenic trioxide (ATO) - based regimen in newly diagnosed cases of acute promyelocytic leukemia (APL). The concern remained about the long-term outcome of th...
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