- Epigenetic Markers in Rectal Cancer
[作者：Xu, L; Czito, BG; Willett, CG,期刊：Clinical Cancer Research, 页码：2699-2701 , 文章类型： Article，,卷期：2010年16-10]
- DNA methylation changes in rectal cancer may serve as a new screening marker and a tool for monitoring recurrence. Importantly, these changes may also function as a predictive marker to allow appropriate exclusion of (ne...
- Integration of Epidermal Growth Factor Receptor Inhibitors with Preoperative Chemoradiation
[作者：Debucquoy, A; Machiels, JP; McBride, WH; Haustermans, K,期刊：Clinical Cancer Research, 页码：2709-2714 , 文章类型： Article，,卷期：2010年16-10]
- In many different cancer cell types, the epidermal growth factor receptor (EGFR) pathway becomes hyperactivated because of overproduction of the ligand, overproduction of the receptor, or constitutive activation of the r...
- Differentiation Therapy Exerts Antitumor Effects on Stem-like Glioma Cells
[作者：Campos, B; Wan, F; Farhadi, M; Ernst, A; Zeppernick, F; Tagscherer, KE; Ahmadi, R; Lohr, J; Dictus, C; Gdynia, G; Combs, SE; Goidts, V; Helmke, BM; Eckstein, V; Roth, W; Beckhove, P; Lichter, P; Unterberg, A; Radlwimmer, B; Herold-Mende, C,期刊：Clinical Cancer Research, 页码：2715-2728 , 文章类型： Article，,卷期：2010年16-10]
- Purpose: Stem-like tumor cells comprise a highly tumorigenic and therapy-resistant tumor subpopulation, which is believed to substantially influence tumor initiation and therapy resistance in glioma. Currently, therapeut...
- Graft-versus-Leukemia Antigen CML66 Elicits Coordinated B-Cell and T-Cell Immunity after Donor Lymphocyte Infusion
[作者：Zhang, WD; Choi, J; Zeng, WY; Rogers, SA; Alyea, EP; Rheinwald, JG; Canning, CM; Brusic, V; Sasada, T; Reinherz, EL; Ritz, J; Soiffer, RJ; Wu, CJ,期刊：Clinical Cancer Research, 页码：2729-2739 , 文章类型： Article，,卷期：2010年16-10]
- Purpose: The target antigens of graft-versus-leukemia that are tumor associated are incompletely characterized.Experimental Design: We examined responses developing against CML66, an immunogenic antigen preferentially ex...
- Activation of beta-Catenin by Hypoxia in Hepatocellular Carcinoma Contributes to Enhanced Metastatic Potential and Poor Prognosis
[作者：Liu, LA; Zhu, XD; Wang, WQ; Shen, YA; Qin, Y; Ren, ZG; Sun, HC; Tang, ZY,期刊：Clinical Cancer Research, 页码：2740-2750 , 文章类型： Article，,卷期：2010年16-10]
- Purpose: Aberrant activation of beta-catenin contributes to the malignant phenotype in hepatocellular carcinoma (HCC). Hypoxia is also known to promote HCC invasion and metastasis. However, the association between beta-c...
- DNMT3L Is a Novel Marker and Is Essential for the Growth of Human Embryonal Carcinoma
[作者：Minami, K; Chano, T; Kawakami, T; Ushida, H; Kushima, R; Okabe, H; Okada, Y; Okamoto, K,期刊：Clinical Cancer Research, 页码：2751-2759 , 文章类型： Article，,卷期：2010年16-10]
- Purpose: Testicular germ cell tumors (TGCT) have a unique epigenetic profile distinct from that of other types of cancer. Elucidation of these properties has a potential to identify novel markers for TGCTs.Experimental D...
- Efficacy, Biodistribution, and Pharmacokinetics of CD22-Targeted Pegylated Liposomal Doxorubicin in a B-cell Non-Hodgkin's Lymphoma Xenograft Mouse Model
[作者：Tuscano, JM; Martin, SM; Ma, YP; Zamboni, W; O'Donnell, RT,期刊：Clinical Cancer Research, 页码：2760-2768 , 文章类型： Article，,卷期：2010年16-10]
- Purpose: Non-Hodgkin's lymphoma (NHL) is the sixth most common cause of cancer death in the U. S. Pegylated liposomal doxorubicin (PLD) is a liposomal form of doxorubicin (DXR) that causes less toxicity than does free DX...
- MicroRNA Microarray Analysis of Human Adrenocortical Tumors Identifies miR-195 and miR-483-5p as Predictors of Poor Prognosis in Adrenocortical Cancer - Response
[作者：Soon, PSH; Tacon, LJ; Clifton-Bligh, RJ; Robinson, BG; Sidhu, SB; Campbell, PR; Gill, AJ; Bambach, CP; Sywak, MS; Yeh, MW; Wong, SG,期刊：Clinical Cancer Research, 页码：U24-2916 , 文章类型： Letter，,卷期：2010年16-10]
-
- Two Distinct Mechanisms of Augmented Antitumor Activity by Modulation of Immunostimulatory/Inhibitory Signals
[作者：Mitsui, J; Nishikawa, H; Muraoka, D; Wang, LA; Noguchi, T; Sato, E; Kondo, S; Allison, JP; Sakaguchi, S; Old, LJ; Kato, T; Shiku, H,期刊：Clinical Cancer Research, 页码：2781-2791 , 文章类型： Article，,卷期：2010年16-10]
- Purpose: Blockade of CTL-associated antigen-4 (CTLA-4), an inhibitory immunomodulatory molecule on T cells, has been shown to enhance T-cell responses and induce tumor rejection, and a number of clinical trials with anti...
- New Molecular and Biological Mechanism of Antitumor Activities of KW-2478, a Novel Nonansamycin Heat Shock Protein 90 Inhibitor, in Multiple Myeloma Cells
[作者：Nakashima, T; Ishii, T; Tagaya, H; Seike, T; Nakagawa, H; Kanda, Y; Akinaga, S; Soga, S; Shiotsu, Y,期刊：Clinical Cancer Research, 页码：2792-2802 , 文章类型： Article，,卷期：2010年16-10]
- Purpose: The heat shock protein 90 (Hsp90) plays an important role in chaperoning oncogenic client proteins in multiple myeloma (MM) cells, and several Hsp90 inhibitors have shown antitumor activities both in vitro and i...
- Tumor Metabolism and Blood Flow as Assessed by Positron Emission Tomography Varies by Tumor Subtype in Locally Advanced Breast Cancer
[作者：Specht, JM; Kurland, BF; Montgomery, SK; Dunnwald, LK; Doot, RK; Gralow, JR; Ellis, GK; Linden, HM; Livingston, RB; Allison, KH; Schubert, EK; Mankoff, DA,期刊：Clinical Cancer Research, 页码：2803-2810 , 文章类型： Article，,卷期：2010年16-10]
- Purpose: Dynamic positron emission tomography (PET) imaging can identify patterns of breast cancer metabolism and perfusion in patients receiving neoadjuvant chemotherapy (NC) that are predictive of response. This analys...
- Identification of a Quantitative MINT Locus Methylation Profile Predicting Local Regional Recurrence of Rectal
[作者：de Maat, MFG; van de Velde, CJH; Benard, A; Putter, H; Morreau, H; van Krieken, JHJM; Klein-Kranenbarg, EM; de Graaf, EJ; Tollenaar, RAEM; Hoon, DSB,期刊：Clinical Cancer Research, 页码：2811-2818 , 文章类型： Article，,卷期：2010年16-10]
- Purpose: Risk assessment for locoregional disease recurrence would be highly valuable in preoperative treatment planning for patients undergoing primary rectal tumor resection. Epigenetic aberrations such as DNA methylat...
- Susceptibility Loci Associated with Prostate Cancer Progression and Mortality
[作者：Gallagher, DJ; Vijai, J; Cronin, AM; Bhatia, J; Vickers, AJ; Gaudet, MM; Fine, S; Reuter, V; Scher, HI; Hallden, C; Dutra-Clarke, A; Klein, RJ; Scardino, PT; Eastham, JA; Lilja, H; Kirchhoff, T; Offit, K,期刊：Clinical Cancer Research, 页码：2819-2832 , 文章类型： Article，,卷期：2010年16-10]
- Purpose: Prostate cancer is a heterogenous disease with a variable natural history that is not accurately predicted by currently used prognostic tools.Experimental Design: We genotyped 798 prostate cancer cases of Ashken...
|