- Endothelial Cells Are Essential for the Self-Renewal and Repopulation of Notch-Dependent Hematopoietic Stem Cells
[作者:Butler, JM; Nolan, DJ; Vertes, EL; Varnum-Finney, B; Kobayashi, H; Hooper, AT; Seandel, M; Shido, K; White, IA; Kobayashi, M; Witte, L; May, C; Shawber, C; Kimura, Y; Kitajewski, J; Rosenwaks, Z; Bernstein, ID; Rafii, S,期刊:Cell Stem Cell, 页码:251-264 , 文章类型: Article,,卷期:2010年6-3]
- Bone marrow endothelial cells (ECs) are essential for reconstitution of hematopoiesis, but their role in self-renewal of long-term hematopoietic stem cells (LT-HSCs) is unknown. We have developed angiogenic models to dem...
- Poised Lineage Specification in Multipotential Hematopoietic Stem and Progenitor Cells by the Polycomb Protein Bmi1
[作者:Oguro, H; Yuan, J; Ichikawa, H; Ikawa, T; Yamazaki, S; Kawamoto, H; Nakauchi, H; Iwama, A,期刊:Cell Stem Cell, 页码:279-286 , 文章类型: Article,,卷期:2010年6-3]
- Polycomb group (PcG) proteins are essential regulators of stem cells. PcG and trithorax group proteins mark developmental regulator gene promoters with bivalent domains consisting of overlapping repressive and activating...
- Unleashing Cardiopoiesis: A Novel Role for G-CSF
[作者:Noseda, M; Schneider, MD,期刊:Cell Stem Cell, 页码:188-189 , 文章类型: Editorial Material,,卷期:2010年6-3]
- Identifying pathways for cardiac muscle creation is a paramount objective of cardiac stem cell biology. In this issue of Cell Stem Cell, Shimoji and colleagues (2010) report the unforeseen ability of granulocyte colony-s...
- Cadherin-Based Adhesion Is a Potential Target for Niche Manipulation to Protect Hematopoietic Stem Cells in Adult Bone Marrow
[作者:Hosokawa, K; Arai, F; Yoshihara, H; Iwasaki, H; Hembree, M; Yin, T; Nakamura, Y; Gomei, Y; Takubo, K; Shiama, H; Matsuoka, S; Li, L; Suda, T,期刊:Cell Stem Cell, 页码:194-198 , 文章类型: Article,,卷期:2010年6-3]
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- Conserved and Divergent Roles of FGF Signaling in Mouse Epiblast Stem Cells and Human Embryonic Stem Cells
[作者:Greber, B; Wu, GM; Bernemann, C; Joo, JY; Han, DW; Ko, K; Tapia, N; Sabour, D; Sterneckert, J; Tesar, P; Scholer, HR,期刊:Cell Stem Cell, 页码:215-226 , 文章类型: Article,,卷期:2010年6-3]
- Mouse epiblast stem cells (EpiSCs) are cultured with FGF2 and Activin A, like human embryonic stem cells (hESCs), but the action of the associated pathways in EpiSCs has not been well characterized. Here, we show that ac...
- G-CSF Promotes the Proliferation of Developing Cardiomyocytes In Vivo and in Derivation from ESCs and iPSCs
[作者:Shimoji, K; Yuasa, S; Onizuka, T; Hattori, F; Tanaka, T; Hara, M; Ohno, Y; Chen, H; Egasgira, T; Seki, T; Yae, K; Koshimizu, U; Ogawa, S; Fukuda, K,期刊:Cell Stem Cell, 页码:227-237 , 文章类型: Article,,卷期:2010年6-3]
- During a screen for humoral factors that promote cardiomyocyte differentiation from embryonic stem cells (ESCs), we found marked elevation of granulocyte colony-stimulating factor receptor (G-CSFR) mRNA in developing car...
- Embryonic MGE Precursor Cells Grafted into Adult Rat Striatum Integrate and Ameliorate Motor Symptoms in 6-OHDA-Lesioned Rats
[作者:Martinez-Cerdeno, V; Noctor, SC; Espinosa, A; Ariza, J; Parker, P; Orasji, S; Daadi, MM; Bankiewicz, K; Alvarez-Buylla, A; Kriegstein, AR,期刊:Cell Stem Cell, 页码:238-250 , 文章类型: Article,,卷期:2010年6-3]
- We investigated a strategy to ameliorate the motor symptoms of rats that received 6-hydroxydopamine (6-OHDA) lesions, a rodent model of Parkinson's disease, through transplantation of embryonic medial ganglionic eminence...
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