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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共32条记录   Synthesis of All Possible A-ring Diastereomers at the 1-and 3-Positions of 1 alpha,25-Dihydroxy-2 beta-(3-hydroxypropoxy)vitamin D-3 (ED-71) Using C-2-Symmetrical Epoxide as a Common Starting Material [作者：Kubodera, N; Hatakeyama, S,期刊：Anticancer Research, 页码：3571-3578 , 文章类型： Article，,卷期：2009年29-9] The active vitamin D-3, 1a,25-dihydroxyvitamin D-3 (1,25(OH)(2)D-3), is now well recognized as a potent regulator of cell proliferation and differentiation in addition to possessing a regulatory effect on calcium and pho... Antiproliferative and Calcemic Actions of Trans-Decalin CD-Ring Analogs of 1,25-Dihydroxyvitamin D-3 [作者：Eelen, G; Verlinden, L; Laureys, J; Marcelis, S; De Clercq, P; Mathieu, C; Bouillon, R; Verstuyf, A,期刊：Anticancer Research, 页码：3579-3584 , 文章类型： Article，,卷期：2009年29-9] Background: 1,25-Dihydroxyvitamin D-3 [1,25(OH)(2)D-3] has potent antiproliferative actions but calcemic effects obstruct its application in the treatment of hyperproliferative disorders. Therefore, analogs of 1,25(OH)(2... Microarray Analysis of MCF-7 Breast Cancer Cells Treated with 1,25-Dihydroxyvitamin D-3 or a 17-Methyl-D-ring Analog [作者：Vanoirbeek, E; Eelen, G; Verlinden, L; Marchal, K; Engelen, K; De Moor, B; Beullens, I; Marcelis, S; De Clercq, P; Bouillon, R; Verstuyf, A,期刊：Anticancer Research, 页码：3585-3590 , 文章类型： Article，,卷期：2009年29-9] Background: 1 alpha,25-dihydroxyvitamin D-3 [1,25-(OH)(2)D-3] is the biological active form of vitamin D. Its antiproliferative capacities make it a potential drug to treat diseases such as cancer. The clinical use of 1,... Fish Oil Enhances the Antiproliferative Effect of 1 alpha,25-Dihydroxyvitamin D-3 on Liver Cancer Cells [作者：Chiang, KC; Persons, KS; Istfan, NW; Holick, MF; Chen, TC,期刊：Anticancer Research, 页码：3591-3596 , 文章类型： Article，,卷期：2009年29-9] Background: Laboratory and epidemiological studies have indicated that la,25-dihydroxyvitamin D-3 [1 alpha,25(OH)(2)D-3] and dietary omega 3 (omega 3)-polyunsaturated fatty acids (PUFAs) are capable of inhibiting the pro... Current Impediments to Acceptance of the Ultraviolet-B-Vitamin D-Cancer Hypothesis [作者：Grant, WB; Boucher, BJ,期刊：Anticancer Research, 页码：3597-3604 , 文章类型： Article，,卷期：2009年29-9] The ultraviolet-B (UVB)-vitamin D-cancer hypothesis was proposed in 1980. There have been numerous ecological, observational and other studies of the hypothesis. There are about 14 types of cancer for which it seems to a... A Phase II Trial of Calcitriol and Naproxen in Recurrent Prostate Cancer [作者：Srinivas, S; Feldman, D,期刊：Anticancer Research, 页码：3605-3610 , 文章类型： Article，,卷期：2009年29-9] Background: Androgen-deprivation therapy is commonly used in patients with progressive prostate cancer (PCa), but can be associated with unpleasant side-effects. The objective of the study was to determine whether treatm... Expression of Prostaglandin Metabolising Enzymes COX-2 and 15-PGDH and VDR in Human Granulosa Cells [作者：Thill, M; Becker, S; Fischer, D; Cordes, T; Hornemann, A; Diedrich, K; Salehn, D; Friedrich, M,期刊：Anticancer Research, 页码：3611-3618 , 文章类型： Article，,卷期：2009年29-9] Background: Prostaglandins (PGs) within the periovulatory follicle are essential for various female reproductive functions such as follicular development and maturation. In animal models, granulosa cells express the PG s... Prostaglandin Metabolizing Enzymes in Correlation with Vitamin D Receptor in Benign and Malignant Breast Cell Lines [作者：Thill, M; Fischer, D; Becker, S; Cordes, T; Dittmer, C; Diedrich, K; Salehin, D; Friedrich, M,期刊：Anticancer Research, 页码：3619-3625 , 文章类型： Article，,卷期：2009年29-9] Background: The antiproliferative effects of calcitriol (1,25(OH)(2)D-3) mediated via the vitamin D receptor (VDR), render the biologically active form of vitamin D a promising target in breast cancer therapy. Furthermor... 25-Hydroxyvitamin D-3 1 alpha-Hydroxylase Splice Variants in Benign and Malignant Ovarian Cell Lines and Tissue [作者：Fischer, D; Thome, M; Becker, S; Cordes, T; Diedrich, K; Friedrich, M; Thill, M,期刊：Anticancer Research, 页码：3627-3633 , 文章类型： Article，,卷期：2009年29-9] Calcitriol is judged to have a positive effect on control of the immune system, cell growth and differentiation and therefore, the prevention of cancer genesis. The aim of this study was to detect any possible difference... Expression of 25-Hydroxyvitamin D-3-24-Hydroxylase in Benign and Malignant Ovarian Cell Lines and Tissue [作者：Fischer, D; Thome, M; Becker, S; Cordes, T; Diedrich, K; Friedrich, M; Thill, M,期刊：Anticancer Research, 页码：3635-3639 , 文章类型： Article，,卷期：2009年29-9] Calcitriol (1,25-dihydroxyvitamin D-3, 1,25(OH)(2)D-3) plays a pivotal role in maintaining calcium and phosphate homeostasis. Aside from that, it supports the native and attenuates the acquired immune system and has posi... Vitamin D-24-Hydroxylase in Benign and Malignant Breast Tissue and Cell Lines [作者：Fischer, D; Becker, S; Cordes, T; Bucker, B; Diedrich, K; Friedrich, M; Salehin, D; Thill, M,期刊：Anticancer Research, 页码：3641-3645 , 文章类型： Article，,卷期：2009年29-9] Tissue-specific expression of 25-hydroxyvitamin D1 alpha-hydroxylase (1 alpha-OHase) and vitamin D-hydroxylase (24-OHase) may act as the pivotal link between 25-hydroxyvitamin D-3 (25(OH)D-3) serum levels and the antican... Cross-talk between Vitamin D Receptor (VDR)- and Peroxisome Proliferator-activated Receptor (PPAR)-signaling in Melanoma Cells [作者：Sertznig, P; Dunlop, T; Seifert, M; Tilgen, W; Reichrath, J,期刊：Anticancer Research, 页码：3647-3658 , 文章类型： Article，,卷期：2009年29-9] The expression and signaling of the vitamin D receptor (VDR) and peroxisome proliferator-activated receptor (PPAR) alpha, delta, gamma was investigated in the melanoma cell line MeWo. Using real-time PCR, the mRNA of the... Expression of 25-Hydroxyvitamin D-1 alpha-Hydroxylase (1 alpha OHase, CYP27B1) Splice Variants in HaCaT Keratinocytes and Other Skin Cells: Modulation by Culture Conditions and UV-B Treatment In Vitro [作者：Seifert, M; Tilgen, W; Reichrath, J,期刊：Anticancer Research, 页码：3659-3667 , 文章类型： Article，,卷期：2009年29-9] In vitro and in vivo studies have demonstrated that the biologically active vitamin D metabolite 1,25-dihydroxyvitamin D (1,25(OH)(2)D-3, calcitriol) suppresses proliferation and induces differentiation in various cell t... Reduced Serum 25-Hydroxyvitamin D Levels in Stage IV Melanoma Patients [作者：Nurnberg, B; Graber, S; Gartner, B; Geisel, J; Pfohler, C; Schadendorf, D; Tilgen, W; Reichrath, J,期刊：Anticancer Research, 页码：3669-3674 , 文章类型： Article，,卷期：2009年29-9] Background: Reduced serum 25-hydroxyvitamin D-3 (25(OH)D) levels are associated with an increased incidence and an unfavorable outcome of various types of cancer. However, the influence of serum 25(OH)D on the incidence ... How to Optimize Vitamin D Supplementation to Prevent Cancer, Based on Cellular Adaptation and Hydroxylase Enzymology [作者：Vieth, R,期刊：Anticancer Research, 页码：3675-3684 , 文章类型： Article，,卷期：2009年29-9] The question of what makes an 'optimal' vitamin D intake is usually equivalent to, 'what serum 25-hydroxyvitamin D [25(OH)D] do we need to stay above to minimize risk of disease?'. This is a simplistic question that igno... Calcium, Vitamin D and Cancer [作者：Peterlik, M; Grant, WB; Cross, HS,期刊：Anticancer Research, 页码：3687-3698 , 文章类型： Article，,卷期：2009年29-9] A low vitamin D status and inadequate calcium intake are important risk factors for various types of cancer. Ecological studies using solar UV-B exposure as an index of vitamin D-3 photoproduction in the skin found a hig...