- Administration routes affect the quality of immune responses: A cross-sectional evaluation of particulate antigen-delivery systems
[作者:Mohanan, D; Slutter, B; Henriksen-Lacey, M; Jiskoot, W; Bouwstra, JA; Perrie, Y; Kundig, TM; Gander, B; Johansen, P,期刊:Journal of controlled release, 页码:342-349 , 文章类型: Article,,卷期:2010年147-3]
- Particulate delivery systems such as liposomes and polymeric nano- and microparticles are attracting great interest for developing new vaccines. Materials and formulation properties essential for this purpose have been e...
- Effect of injection site on in situ implant formation and drug release in vivo
[作者:Patel, RB; Solorio, L; Wu, HP; Krupka, T; Exner, AA,期刊:Journal of controlled release, 页码:350-358 , 文章类型: Article,,卷期:2010年147-3]
- In situ forming drug delivery implants offer an attractive alternative to pre-formed implant devices for local drug delivery due to their ability to deliver fragile drugs, simple manufacturing process, and less invasive ...
- Sustained delivery of human growth hormone using a polyelectrolyte complex-loaded thermosensitive polyphosphazene hydrogel
[作者:Park, MR; Chun, CJ; Ahn, SW; Ki, MH; Cho, CS; Song, SC,期刊:Journal of controlled release, 页码:359-367 , 文章类型: Article,,卷期:2010年147-3]
- A combined system of polyelectrolyte complex (PEC) and injectable, biodegradable and thermosensitive poly(organophosphazene) hydrogel has been suggested as an injectable depot for a controlled and sustained delivery of h...
- Sunlight triggered photodynamic ultradeformable liposomes against Leishmania braziliensis are also leishmanicidal in the dark
[作者:Montanari, J; Maidana, C; Esteva, MI; Salomon, C; Morilla, MJ; Romero, EL,期刊:Journal of controlled release, 页码:368-376 , 文章类型: Article,,卷期:2010年147-3]
- Being independent of artificial power sources, self administered sunlight triggered photodynamic therapy could be a suitable alternative treatment for cutaneous leishmaniasis, that avoids the need for injectables and the...
- mRNA transfection of cervical carcinoma and mesenchymal stem cells mediated by cationic carriers
[作者:Rejman, J; Tavernier, G; Bavarsad, N; Demeester, J; De Smedt, SC,期刊:Journal of controlled release, 页码:385-391 , 文章类型: Article,,卷期:2010年147-3]
- Messenger RNA encoding luciferase (mLUC) was complexed to the cationic lipids Lipofectamine or DOTAP/DOPE, and to the cationic polymer linear poly(ethyleneimine) (linPEI). The complexes were incubated with HeLa cells and...
- Polymer particle shape independently influences binding and internalization by macrophages
[作者:Sharma, G; Valenta, DT; Altman, Y; Harvey, S; Xie, H; Mitragotri, S; Smith, JW,期刊:Journal of controlled release, 页码:408-412 , 文章类型: Article,,卷期:2010年147-3]
- The interaction of macrophages with micro and nanoparticles (MNPs) is important because these cells clear particles from the circulation, and because they are potential therapeutic targets in inflammatory conditions, ath...
- A simple method to achieve high doxorubicin loading in biodegradable polymersomes
[作者:Sanson, C; Schatz, C; Le Meins, JF; Soum, A; Thevenot, J; Garanger, E; Lecommandoux, S,期刊:Journal of controlled release, 页码:428-435 , 文章类型: Article,,卷期:2010年147-3]
- Doxorubicin (Dox), an anthracycline anticancer drug, was successfully incorporated into block copolymer vesicles of poly(trimethylene carbonate)-b-poly(L-glutamic acid) (PTMC-b-PGA) by a solvent-displacement (nanoprecipi...
- Size of thermosensitive liposomes influences content release
[作者:Hossann, M; Wang, TT; Wiggenhorn, M; Schmidt, R; Zengerle, A; Winter, G; Eibl, H; Peller, M; Reiser, M; Issels, RD; Lindner, LH,期刊:Journal of controlled release, 页码:436-443 , 文章类型: Article,,卷期:2010年147-3]
- Thermosensitive liposomes (TSL) in combination with regional hyperthermia represent a powerful tool for tumor specific drug delivery. The objective of this study was to investigate the influence of vesicle size on the bi...
- Drug delivery system based on chronobiology-A review
[作者:Mandal, AS; Biswas, N; Karim, KM; Guha, A; Chatterjee, S; Behera, M; Kuotsu, K,期刊:Journal of controlled release, 页码:314-325 , 文章类型: Review,,卷期:2010年147-3]
- With the advancement in the field of chronobiology, modern drug delivery approaches have been elevated to a new concept of chronopharmacology i.e. the ability to deliver the therapeutic agent to a patient in a staggered ...
- Dose sparing enabled by skin immunization with influenza virus-like particle vaccine using microneedles
[作者:Quan, FS; Kim, YC; Compans, RW; Prausnitz, MR; Kang, SM,期刊:Journal of controlled release, 页码:326-332 , 文章类型: Article,,卷期:2010年147-3]
- To address the limitations of conventional influenza vaccine manufacturing and delivery, this study investigated administration of virus-like particle (VLP) influenza vaccine using a microneedle patch. The goal was to de...
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