- Proliferative and transcriptional identity of distinct classes of neural precursors in the mammalian olfactory epithelium
[作者：Tucker, ES; Lehtinen, MK; Maynard, T; Zirlinger, M; Dulac, C; Rawson, N; Pevny, L; LaMantia, AS,期刊：Development, 页码：2471-2481 , 文章类型： Article，,卷期：2010年137-15]
- Neural precursors in the developing olfactory epithelium (OE) give rise to three major neuronal classes - olfactory receptor (ORNs), vomeronasal (VRNs) and gonadotropin releasing hormone (GnRH) neurons. Nevertheless, the...
- Ring1B and Suv39h1 delineate distinct chromatin states at bivalent genes during early mouse lineage commitment
[作者：Alder, O; Lavial, F; Helness, A; Brookes, E; Pinho, S; Chandrashekran, A; Arnaud, P; Pombo, A; O'Neill, L; Azuara, V,期刊：Development, 页码：2483-2492 , 文章类型： Article，,卷期：2010年137-15]
- Pluripotent cells develop within the inner cell mass of blastocysts, a mosaic of cells surrounded by an extra-embryonic layer, the trophectoderm. We show that a set of somatic lineage regulators (including Hox, Gata and ...
- Kcnq1ot1 noncoding RNA mediates transcriptional gene silencing by interacting with Dnmt1
[作者：Mohammad, F; Mondal, T; Guseva, N; Pandey, GK; Kanduri, C,期刊：Development, 页码：2493-2499 , 文章类型： Article，,卷期：2010年137-15]
- A long noncoding RNA, Kcnq1ot1, regulates the expression of both ubiquitously and tissue-specific imprinted genes within the Kcnq1 domain. However, the functional sequences of the Kcnq1ot1 RNA that mediate lineage-specif...
- hand2 and Dlx genes specify dorsal, intermediate and ventral domains within zebrafish pharyngeal arches
[作者：Talbot, JC; Johnson, SL; Kimmel, CB,期刊：Development, 页码：2506-2516 , 文章类型： Article，,卷期：2010年137-15]
- The ventrally expressed secreted polypeptide endothelin1 (Edn1) patterns the skeleton derived from the first two pharyngeal arches into dorsal, intermediate and ventral domains. Edn1 activates expression of many genes, i...
- Oriented cell motility and division underlie early limb bud morphogenesis
[作者：Wyngaarden, LA; Vogeli, KM; Ciruna, BG; Wells, M; Hadjantonakis, AK; Hopyan, S,期刊：Development, 页码：2551-2558 , 文章类型： Article，,卷期：2010年137-15]
- The vertebrate limb bud arises from lateral plate mesoderm and its overlying ectoderm. Despite progress regarding the genetic requirements for limb development, morphogenetic mechanisms that generate early outgrowth rema...
- Scapula development is governed by genetic interactions of Pbx1 with its family members and with Emx2 via their cooperative control of Alx1
[作者：Capellini, TD; Vaccari, G; Ferretti, E; Fantini, S; He, M; Pellegrini, M; Quintana, L; Di Giacomo, G; Sharpe, J; Selleri, L; Zappavigna, V,期刊：Development, 页码：2559-2569 , 文章类型： Article，,卷期：2010年137-15]
- The genetic pathways underlying shoulder blade development are largely unknown, as gene networks controlling limb morphogenesis have limited influence on scapula formation. Analysis of mouse mutants for Pbx and Emx2 gene...
- Opposite roles of DMRT1 and its W-linked paralogue, DM-W, in sexual dimorphism of Xenopus laevis: implications of a ZZ/ZW-type sex-determining system
[作者：Yoshimoto, S; Ikeda, N; Izutsu, Y; Shiba, T; Takamatsu, N; Ito, M,期刊：Development, 页码：2519-2526 , 文章类型： Article，,卷期：2010年137-15]
- A Y-linked gene, DMY/dmrt1bY, in teleost fish medka and a Z-linked gene, DMRT1, in chicken are both required for male sex determination. We recently isolated a W-linked gene, DM-W, as a paralogue of DMRT1 in Xenopus laev...
- Mib-Jag1-Notch signalling regulates patterning and structural roles of the notochord by controlling cell-fate decisions
[作者：Yamamoto, M; Morita, R; Mizoguchi, T; Matsuo, H; Isoda, M; Ishitani, T; Chitnis, AB; Matsumoto, K; Crump, JG; Hozumi, K; Yonemura, S; Kawakami, K; Itoh, M,期刊：Development, 页码：2527-2537 , 文章类型： Article，,卷期：2010年137-15]
- In the developing embryo, cell-cell signalling is necessary for tissue patterning and structural organization. During midline development, the notochord plays roles in the patterning of its surrounding tissues while form...
- Neuronal Nogo-A regulates neurite fasciculation, branching and extension in the developing nervous system
[作者：Petrinovic, MM; Duncan, CS; Bourikas, D; Weinman, O; Montani, L; Schroeter, A; Maerki, D; Sommer, L; Stoeckli, ET; Schwab, ME,期刊：Development, 页码：2539-2550 , 文章类型： Article，,卷期：2010年137-15]
- Wiring of the nervous system is a multi-step process involving complex interactions of the growing fibre with its tissue environment and with neighbouring fibres. Nogo-A is a membrane protein enriched in the adult centra...
- Negative control of Smad activity by ectodermin/Tif1 gamma patterns the mammalian embryo
[作者：Morsut, L; Yan, KP; Enzo, E; Aragona, M; Soligo, SM; Wendling, O; Mark, M; Khetchoumian, K; Bressan, G; Chambon, P; Dupont, S; Losson, R; Piccolo, S,期刊：Development, 页码：2571-2578 , 文章类型： Article，,卷期：2010年137-15]
- The definition of embryonic potency and induction of specific cell fates are intimately linked to the tight control over TGF beta signaling. Although extracellular regulation of ligand availability has received considera...
- MEX-5 enrichment in the C. elegans early embryo mediated by differential diffusion
[作者：Daniels, BR; Dobrowsky, TM; Perkins, EM; Sun, SX; Wirtz, D,期刊：Development, 页码：2579-2585 , 文章类型： Article，,卷期：2010年137-15]
- Specification of germline and somatic cell lineages in C. elegans originates in the polarized single-cell zygote. Several cell-fate determinants are partitioned unequally along the anterior-posterior axis of the zygote, ...
- A model of Costeff Syndrome reveals metabolic and protective functions of mitochondrial OPA3
[作者：Pei, WH; Kratz, LE; Bernardini, I; Sood, R; Yokogawa, T; Dorward, H; Ciccone, C; Kelley, RI; Anikster, Y; Burgess, HA; Huizing, M; Feldman, B,期刊：Development, 页码：2587-2596 , 文章类型： Article，,卷期：2010年137-15]
- Costeff Syndrome, which is caused by mutations in the OPTIC ATROPHY 3 (OPA3) gene, is an early-onset syndrome characterized by urinary excretion of 3-methylglutaconic acid (MGC), optic atrophy and movement disorders, inc...
- Spps, a Drosophila Sp1/KLF family member, binds to PREs and is required for PRE activity late in development
[作者：Brown, JL; Kassis, JA,期刊：Development, 页码：2597-2602 , 文章类型： Article，,卷期：2010年137-15]
- The Polycomb group of proteins (PcG) is important for transcriptional repression and silencing in all higher eukaryotes. In Drosophila, PcG proteins are recruited to the DNA by Polycomb-group response elements (PREs), re...
- TSC1/2 tumour suppressor complex maintains Drosophila germline stem cells by preventing differentiation
[作者：Sun, P; Quan, ZH; Zhang, BD; Wu, TQ; Xi, RW,期刊：Development, 页码：2461-2469 , 文章类型： Article，,卷期：2010年137-15]
- Tuberous sclerosis complex human disease gene products TSC1 and TSC2 form a functional complex that negatively regulates target of rapamycin (TOR), an evolutionarily conserved kinase that plays a central role in cell gro...
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