- Association between imatinib-resistant BCR-ABL mutation-negative leukemia and persistent activation of LYN kinase
[作者：Wu, J; Meng, F; Kong, LY; Peng, ZH; Ying, YM; Bornmann, WG; Darnay, BG; Lamothe, B; Sun, HS; Talpaz, M; Donato, NJ,期刊：Journal of the National Cancer Institute, 页码：926-939 , 文章类型： Article，,卷期：2008年100-13]
- Background Imatinib is a tyrosine kinase inhibitor that is used to treat chronic myelogenous leukemia (CML). BCR-ABL mutations are associated with failure of imatinib treatment in many CML patients. LYN kinase regulates ...
- CHD5, a tumor suppressor gene deleted from 1p36.31 in neuroblastomas
[作者：Fujita, T; Igarashi, J; Okawa, ER; Gotoh, T; Manne, J; Kolla, V; Kim, J; Zhao, HQ; Pawel, BR; London, WB; Maris, JM; White, PS; Brodeur, GM,期刊：Journal of the National Cancer Institute, 页码：940-949 , 文章类型： Article，,卷期：2008年100-13]
- Background Neuroblastomas are characterized by hemizygous 1p deletions, suggesting that a tumor suppressor gene resides in this region. We previously mapped the smallest region of consistent deletion to a 2-Mb region of ...
- Guanylyl cyclase C-induced immunotherapeutic responses opposing tumor metastases without autoimmunity
[作者：Snook, AE; Stafford, BJ; Li, P; Tan, G; Huang, L; Birbe, R; Schulz, S; Schnell, MJ; Thakur, M; Rothstein, JL; Eisenlohr, LC; Waldman, SA,期刊：Journal of the National Cancer Institute, 页码：950-961 , 文章类型： Article，,卷期：2008年100-13]
- Background One of the greatest impediments to cancer immunotherapy is the paucity of antigens that are tumor specific, sufficiently immunogenic, and shared among patients. Mucosa-restricted antigens that are expressed by...
- Multiple loci with different cancer specificities within the 8q24 gene desert
[作者：Ghoussaini, M; Song, HL; Koessler, T; Al Olama, AA; Kote-Jarai, Z; Driver, KE; Pooley, KA; Ramus, SJ; Kjaer, SK; Hogdall, E; DiCioccio, RA; Whittemore, AS; Gayther, SA; Giles, GG; Guy, M; Edwards, SM; Morrison, J; Donovan, JL; Hamdy, FC; Dearnaley, DP; Ardern-Jones, AT; Hall, AL; O'Brien, LT; Gehr-Swain, BN; Wilkinson, RA; Brown, PM; Hopper, JL; Neal, DE; Pharoah, PDP; Ponder, BAJ; Eeles, RA; Easton, DF; Dunning, AM,期刊：Journal of the National Cancer Institute, 页码：962-966 , 文章类型： Article，,卷期：2008年100-13]
- Recent studies based on genome-wide association, linkage, and admixture scan analysis have reported associations of various genetic variants in 8q24 with susceptibility to breast, prostate, and colorectal cancer. This lo...
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