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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共9条记录   Strategies to Convert PACAP from a Hypophysiotropic Neurohormone Into a Neuroprotective Drug [作者：Bourgault, S; Chatenet, D; Wurtz, O; Doan, ND; Leprince, J; Vaudry, H; Fournier, A; Vaudry, D,期刊：Current Pharmaceutical Design, 页码：1002-1024 , 文章类型： Review，,卷期：2011年17-10] In neurological insults, such as cerebral ischemia and traumatic brain injury, complex molecular mechanisms involving inflammation and apoptosis are known to cause severe neuronal cell loss, emphasizing the necessity of ... Immunomodulatory Roles of VIP and PACAP in Models of Multiple Sclerosis [作者：Abad, C; Waschek, JA,期刊：Current Pharmaceutical Design, 页码：1025-1035 , 文章类型： Review，,卷期：2011年17-10] Multiple sclerosis (MS) is a progressive neurodegenerative disease affecting myelin and axons, which is perpetuated by autoreactive lymphocytes and other inflammatory cell types. Because of the multifactorial nature of t... VIP-induced Neuroprotection of the Developing Brain [作者：Passemard, S; Sokolowska, P; Schwendimann, L; Gressens, P,期刊：Current Pharmaceutical Design, 页码：1036-1039 , 文章类型： Review，,卷期：2011年17-10] Excitotoxicity is a key molecular mechanism of perinatal brain damage and is associated with cerebral palsy and long term cognitive deficits. VIP induces a potent neuroprotection against perinatal excitotoxic white matte... NAP (Davunetide) Provides Functional and Structural Neuroprotection [作者：Gozes, I,期刊：Current Pharmaceutical Design, 页码：1040-1044 , 文章类型： Review，,卷期：2011年17-10] NAP (davunetide) is an eight amino acid peptide ( NAPVSIPQ) that has been shown to provide potent neuroprotection, in vitro and in vivo. In human clinical trials, NAP has been shown to increase memory scores in patients ... VIP and PACAP: Novel Approaches to Brain Functions and Neuroprotection [作者：Shioda, S; Gozes, I,期刊：Current Pharmaceutical Design, 页码：961-961 , 文章类型： Editorial Material，,卷期：2011年17-10] Review on the Protective Effects of PACAP in Models of Neurodegenerative Diseases In Vitro and In Vivo [作者：Reglodi, D; Kiss, P; Lubics, A; Tamas, A,期刊：Current Pharmaceutical Design, 页码：962-972 , 文章类型： Review，,卷期：2011年17-10] Pituitary adenylate cyclase activating polypeptide (PACAP) is a pleiotropic and multifunctional peptide exerting its effects via 3 main receptors (PAC1, VPAC1 and VPAC2). PACAP is now considered to be a potent neurotroph... Role of PACAP in Neural Stem/Progenitor Cell and Astrocyte: from Neural Development to Neural Repair [作者：Nakamachi, T; Farkas, J; Watanabe, J; Ohtaki, H; Dohi, K; Arata, S; Shioda, S,期刊：Current Pharmaceutical Design, 页码：973-984 , 文章类型： Review，,卷期：2011年17-10] After central nervous system (CNS) injury, reactive astrocytes display opposing functions, inducing neural repair and axonal regeneration via the release of growth factors, or forming a glial scar which acts as a barrier... PACAP is Implicated in the Stress Axes [作者：Hashimoto, H; Shintani, N; Tanida, M; Hayata, A; Hashimoto, R; Baba, A,期刊：Current Pharmaceutical Design, 页码：985-989 , 文章类型： Review，,卷期：2011年17-10] Pituitary adenylate cyclase-activating polypeptide (PACAP) is a highly conserved pleiotropic neuropeptide that functions as a neurotransmitter, neuromodulator and neurotrophic factor. Accumulating evidence implicates PAC... The Role of the PACAP Signaling System in Depression [作者：Pinhasov, A; Nesher, E; Gross, M; Turgeman, G; Kreinin, A; Yadid, G,期刊：Current Pharmaceutical Design, 页码：990-1001 , 文章类型： Review，,卷期：2011年17-10] Major Depressive Disorder (MDD) is a psychiatric condition that represents an important public health concern in modern society. Current pharmacological antidepressant treatments improve depressive symptoms through compl...