- Detection of elevated levels of alpha-synuclein oligomers in CSF from patients with Parkinson disease
[作者:Tokuda, T; Qureshi, MM; Ardah, MT; Varghese, S; Shehab, SAS; Kasai, T; Ishigami, N; Tamaoka, A; Nakagawa, M; El-Agnaf, OMA,期刊:Neurology, 页码:1766-1772 , 文章类型: Article,,卷期:2010年75-20]
- Background: To date, there is no accepted clinical diagnostic test for Parkinson disease (PD) that is based on biochemical analysis of blood or CSF. The discovery of mutations in the SNCA gene encoding alpha-synuclein in...
- Modafinil ameliorates excessive daytime sleepiness after traumatic brain injury
[作者:Kaiser, PR; Valko, PO; Werth, E; Thomann, J; Meier, J; Stocker, R; Bassetti, CL; Baumann, CR,期刊:Neurology, 页码:1780-1785 , 文章类型: Article,,卷期:2010年75-20]
- Background: Excessive daytime sleepiness (EDS) and fatigue are common symptoms after traumatic brain injury (TBI), but there is no specific treatment for affected patients. With this pilot study, we aimed at studying the...
- GFAP and S100B are biomarkers of traumatic brain injury An observational cohort study
[作者:Vos, PE; Jacobs, B; Andriessen, TMJC; Lamers, KJB; Borm, GF; Beems, T; Edwards, M; Rosmalen, CF; Vissers, JLM,期刊:Neurology, 页码:1786-1793 , 文章类型: Article,,卷期:2010年75-20]
- Background: Biomarker levels in blood after traumatic brain injury (TBI) may offer diagnostic and prognostic tools in addition to clinical indices. This study aims to validate glial fibrillary acidic protein (GFAP) and S...
- Pregnancy and fetal outcomes after interferon-beta exposure in multiple sclerosis
[作者:Amato, MP; Portaccio, E; Ghezzi, A; Hakiki, B; Zipoli, V; Martinelli, V; Moiola, L; Patti, F; La Mantia, L; Mancardi, GL; Solaro, C; Tola, MR; Pozzilli, C; De Giglio, L; Totaro, R; Lugaresi, A; Di Tommaso, V; Paolicelli, D; Marrosu, MG; Comi, G; Pellegrini, F; Trojano, M,期刊:Neurology, 页码:1794-1802 , 文章类型: Article,,卷期:2010年75-20]
- Objective: To assess pregnancy and fetal outcomes after in utero exposure to interferon-beta (IFN beta) in all pregnancies occurring in women with multiple sclerosis (MS) during the study period, with a specific focus on...
- Vesicular glutamate transporter and cognition in stroke A case-control autopsy study
[作者:Kirvell, SL; Elliott, MS; Kalaria, RN; Hortobagyi, T; Ballard, CG; Francis, PT,期刊:Neurology, 页码:1803-1809 , 文章类型: Article,,卷期:2010年75-20]
- Objectives: Vascular dementia (VaD) accounts for approximately 15%-20% of all dementias, but the relationship of progressive cognitive impairment to neurochemical changes is poorly understood. We have therefore investiga...
- Dietary intake of vitamin D and cognition in older women A large population-based study
[作者:Annweiler, C; Schott, AM; Rolland, Y; Blain, H; Herrmann, FR; Beauchet, O,期刊:Neurology, 页码:1810-1816 , 文章类型: Article,,卷期:2010年75-20]
- Background: Serum vitamin D concentrations are associated with global cognitive function among older adults. The benefits of vitamin D intake to treat or prevent cognitive impairment remain unknown. The objective of this...
- Efficacy and safety of adjunctive ezogabine (retigabine) in refractory partial epilepsy
[作者:Brodie, MJ; Lerche, H; Gil-Nagel, A; Elger, C; Hall, S; Shin, P; Nohria, V; Mansbach, H,期刊:Neurology, 页码:1817-1824 , 文章类型: Article,,卷期:2010年75-20]
- Objective: This study assessed the efficacy and safety of the neuronal potassium channel opener ezogabine (US adopted name; EZG)/retigabine (international nonproprietary name; RTG) as adjunctive therapy for refractory pa...
- Four novel cases of periaxin-related neuropathy and review of the literature
[作者:Marchesi, C; Milani, M; Morbin, M; Cesani, M; Lauria, G; Scaioli, V; Piccolo, G; Fabrizi, GM; Cavallaro, T; Taroni, F; Pareyson, D,期刊:Neurology, 页码:1830-1838 , 文章类型: Article,,卷期:2010年75-20]
- Objective: To report 4 cases of autosomal recessive hereditary neuropathy associated with novel mutations in the periaxin gene (PRX) with a review of the literature. Periaxin protein is required for the maintenance of pe...
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