- Imaging correlates of pathology in corticobasal syndrome
[作者:Whitwell, JL; Jack, CR; Boeve, BF; Parisi, JE; Ahlskog, JE; Drubach, DA; Senjem, ML; Knopman, DS; Petersen, RC; Dickson, DW; Josephs, KA,期刊:Neurology, 页码:1879-1887 , 文章类型: Article,,卷期:2010年75-21]
- Background: Corticobasal syndrome (CBS) can be associated with different underlying pathologies that are difficult to predict based on clinical presentation. The aim of this study was to determine whether patterns of atr...
- The 32-year relationship between cholesterol and dementia from midlife to late life
[作者:Mielke, MM; Zandi, PP; Shao, H; Waern, M; Ostling, S; Guo, X; Bjorkelund, C; Lissner, L; Skoog, I; Gustafson, DR,期刊:Neurology, 页码:1888-1895 , 文章类型: Article,,卷期:2010年75-21]
- Background: Cellular and animal studies suggest that hypercholesterolemia contributes to Alzheimer disease (AD). However, the relationship between cholesterol and dementia at the population level is less clear and may va...
- Brain N-acetylaspartate levels correlate with motor function in metachromatic leukodystrophy
[作者:Dali, CI; Hanson, LG; Barton, NW; Fogh, J; Nair, N; Lund, AM,期刊:Neurology, 页码:1896-1903 , 文章类型: Article,,卷期:2010年75-21]
- Background: Late infantile metachromatic leukodystrophy (MLD) is an autosomal recessive lysosomal storage disorder that causes severe demyelination of the nervous system. The neuronal metabolite N-acetylaspartate (NAA) s...
- Afferent baroreflex failure in familial dysautonomia
[作者:Norcliffe-Kaufmann, L; Axelrod, F; Kaufmann, H,期刊:Neurology, 页码:1904-1911 , 文章类型: Article,,卷期:2010年75-21]
- Background: Familial dysautonomia (FD) is due to a genetic deficiency of the protein IKAP, which affects development of peripheral neurons. Patients with FD display complex abnormalities of the baroreflex of unknown caus...
- Aspiration and swallowing in Parkinson disease and rehabilitation with EMST A randomized trial
[作者:Troche, MS; Okun, MS; Rosenbek, JC; Musson, N; Fernandez, HH; Rodriguez, R; Romrell, J; Pitts, T; Wheeler-Hegland, KM; Sapienza, CM,期刊:Neurology, 页码:1912-1919 , 文章类型: Article,,卷期:2010年75-21]
- Objective: Dysphagia is the main cause of aspiration pneumonia and death in Parkinson disease (PD) with no established restorative behavioral treatment to date. Reduced swallow safety may be related to decreased elevatio...
- Depressive symptoms in PD correlate with higher 5-HTT binding in raphe and limbic structures
[作者:Politis, M; Wu, K; Loane, C; Turkheimer, FE; Molloy, S; Brooks, DJ; Piccini, P,期刊:Neurology, 页码:1920-1927 , 文章类型: Article,,卷期:2010年75-21]
- Background: Depression associated with Parkinson disease (PD) has a different symptom profile to endogenous depression. The etiology of depression in PD remains uncertain though abnormal serotonergic neurotransmission co...
- Head position during resting modifies spontaneous daytime decrease of downbeat nystagmus
[作者:Spiegel, R; Kalla, R; Rettinger, N; Schneider, E; Straumann, D; Marti, S; Glasauer, S; Brandt, T; Strupp, M,期刊:Neurology, 页码:1928-1932 , 文章类型: Article,,卷期:2010年75-21]
- Background: The intensity of downbeat nystagmus (DBN) decreases during the daytime when the head is in upright position.Objective: This prospective study investigated whether resting in different head positions (upright,...
- Brainstem lesions in clinically isolated syndromes
[作者:Tintore, M; Rovira, A; Arrambide, G; Mitjana, R; Rio, J; Auger, C; Nos, C; Edo, MC; Castillo, J; Horga, A; Perez-Miralles, F; Huerga, E; Comabella, M; Sastre-Garriga, J; Montalban, X,期刊:Neurology, 页码:1933-1938 , 文章类型: Article,,卷期:2010年75-21]
- Background: Number of baseline lesions has been shown to predict future attacks and disability in clinically isolated syndromes (CIS).Objective: To investigate the role of baseline infratentorial lesions in long-term pro...
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