- Targeted Drug Delivery--Quo Vadis?
[作者:Petrak, K,期刊:Drug Development Research, 页码:59-65 , 文章类型: Article,,卷期:2012年73-2]
- While business predictions suggest that 19 companies will have new or improved targeted drug delivery products on the market by 2018, no effective drug-targeting systems have as yet been developed for use as human therap...
- Uricases as Therapeutic Agents to Treat Refractory Gout: Current States and Future Directions
[作者:Yang, XL; Yuan, YH; Zhan, CG; Liao, F,期刊:Drug Development Research, 页码:66-72 , 文章类型: Article,,卷期:2012年73-2]
- Treatment of refractory gout remains a challenge on drug development. While pegloticase, a recombinant mammalian uricase modified with monomethoxyl poly(ethylene glycol) (mPEG) is effective in treating refractory gout, a...
- Synthesis and activity evaluation of 3'-floxuridinyl 4-[3-(3, 5-di-t-butyl-4-methoxyphenyl)-3-oxo-propenyl]benzoate: in vitro and in vivo as a potential dual-acting antitumor prodrug
[作者:Du, LX; Jin, JQ; Wu, W; Chen, JG; Shan, AL; Zhang, SQ,期刊:Drug Development Research, 页码:73-81 , 文章类型: Article,,卷期:2012年73-2]
- BOBA (4-[3-(3, 5-di-tert-butyl-4-methoxyphenyl)-3-oxo-propenyl]benzoic acid), a substituted chalcone derivative, exhibits an excellent inducing differentiation on neoplastic cellular differentiation. FUDR (5-fluoro-2'-de...
- Anti-Inflammatory and Antiproliferative Activities of Organic Fractions from the Mediterranean Brown Seaweed, Cystoseira Compressa
[作者:Mhadhebi, L; Dellai, A; Clary-Laroche, A; Ben Said, R; Robert, J; Bouraoui, A,期刊:Drug Development Research, 页码:82-89 , 文章类型: Article,,卷期:2012年73-2]
- The inability to cure many diseases, such as cancer and arthritis, has stimulated the need for the development of new drugs from natural sources. Of all natural sources, the marine environment is clearly the last great f...
- Neuropharmacological and Toxicity Evaluations of Ethanol Extract from Rhodiola Rosea
[作者:Montiel-Ruiz, RM; Roa-Coria, JE; Patino-Camacho, SI; Flores-Murrieta, FJ; Deciga-Campos, M,期刊:Drug Development Research, 页码:106-113 , 文章类型: Article,,卷期:2012年73-2]
- Rhodiola rosea is a popular medicinal plant that is commonly used as an adaptogen in folklore medicine in Europe and Asia due to its ability to increase an organism's resistance to physical, chemical and biological stres...
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