- The Vesicular Acetylcholine Transporter Is Required for Neuromuscular Development and Function
[作者：de Castro, BM; De Jaeger, X; Martins-Silva, C; Lima, RDF; Amaral, E; Menezes, C; Lima, P; Neves, CML; Pires, RG; Gould, TW; Welch, I; Kushmerick, C; Guatimosim, C; Izquierdo, I; Cammarota, M; Rylett, RJ; Gomez, MV; Caron, MG; Oppenheim, RW; Prado, MAM; Prado, VF,期刊：Molecular and Cellular Biology, 页码：5238-5250 , 文章类型： Article，,卷期：2009年29-19]
- The vesicular acetylcholine (ACh) transporter (VAChT) mediates ACh storage by synaptic vesicles. However, the VAChT-independent release of ACh is believed to be important during development. Here we generated VAChT knock...
- The Saccharomyces cerevisiae Rad6 Postreplication Repair and Siz1/Srs2 Homologous Recombination-Inhibiting Pathways Process DNA Damage That Arises in asf1 Mutants
[作者：Kats, ES; Enserink, JM; Martinez, S; Kolodner, RD,期刊：Molecular and Cellular Biology, 页码：5226-5237 , 文章类型： Article，,卷期：2009年29-19]
- The Asf1 and Rad6 pathways have been implicated in a number of common processes such as suppression of gross chromosomal rearrangements (GCRs), DNA repair, modification of chromatin, and proper checkpoint functions. We e...
- The Nucleosome Binding Protein HMGN3 Modulates the Transcription Profile of Pancreatic beta Cells and Affects Insulin Secretion
[作者：Ueda, T; Furusawa, T; Kurahashi, T; Tessarollo, L; Bustin, M,期刊：Molecular and Cellular Biology, 页码：5264-5276 , 文章类型： Article，,卷期：2009年29-19]
- Improper glucose-stimulated insulin secretion from pancreatic beta cells is a major factor in the onset of type 2 diabetes. We now report that HMGN3, a nuclear protein that binds to nucleosomes and affects chromatin func...
- Assembly of an Export-Competent mRNP Is Needed for Efficient Release of the 3 '-End Processing Complex after Polyadenylation
[作者：Qu, XP; Lykke-Andersen, S; Nasser, T; Saguez, C; Bertrand, E; Jensen, TH; Moore, C,期刊：Molecular and Cellular Biology, 页码：5327-5338 , 文章类型： Article，,卷期：2009年29-19]
- Before polyadenylated mRNA is exported from the nucleus, the 3'-end processing complex is removed by a poorly described mechanism. In this study, we asked whether factors involved in mRNP maturation and export are also r...
- The Polymerase eta Translesion Synthesis DNA Polymerase Acts Independently of the Mismatch Repair System To Limit Mutagenesis Caused by 7,8-Dihydro-8-Oxoguanine in Yeast
[作者：Mudrak, SV; Welz-Voegele, C; Jinks-Robertson, S,期刊：Molecular and Cellular Biology, 页码：5316-5326 , 文章类型： Article，,卷期：2009年29-19]
- Reactive oxygen species are ubiquitous mutagens that have been linked to both disease and aging. The most studied oxidative lesion is 7,8-dihydro-8-oxoguanine (GO), which is often miscoded during DNA replication, resulti...
- The HECT-Type E3 Ubiquitin Ligase AIP2 Inhibits Activation-Induced T-Cell Death by Catalyzing EGR2 Ubiquitination
[作者：Chen, A; Gao, BX; Zhang, JP; McEwen, T; Ye, SQ; Zhang, DN; Fang, DY,期刊：Molecular and Cellular Biology, 页码：5348-5356 , 文章类型： Article，,卷期：2009年29-19]
- E3 ubiquitin ligases, which target specific molecules for proteolytic destruction, have emerged as key regulators of immune functions. Several E3 ubiquitin ligases, including c-Cbl, Cbl-b, GRAIL, Itch, and Nedd4, have be...
- Drosophila FoxO Regulates Organism Size and Stress Resistance through an Adenylate Cyclase
[作者：Mattila, J; Bremer, A; Ahonen, L; Kostiainen, R; Puig, O,期刊：Molecular and Cellular Biology, 页码：5357-5365 , 文章类型： Article，,卷期：2009年29-19]
- Forkhead box class O (FoxO) transcription factors are a family of conserved proteins that regulate the cellular responses to various stimuli, such as energy deprivation, stress, and developmental cues. FoxO proteins are ...
- Selective Anchoring of DNA Methyltransferases 3A and 3B to Nucleosomes Containing Methylated DNA
[作者：Jeong, S; Liang, GN; Sharma, S; Lin, JC; Choi, SH; Han, H; Yoo, CB; Egger, G; Yang, AS; Jones, PA,期刊：Molecular and Cellular Biology, 页码：5366-5376 , 文章类型： Article，,卷期：2009年29-19]
- Proper DNA methylation patterns are essential for mammalian development and differentiation. DNA methyltransferases (DNMTs) primarily establish and maintain global DNA methylation patterns; however, the molecular mechani...
- p85 Associates with Unphosphorylated PTEN and the PTEN-Associated Complex
[作者：Rabinovsky, R; Pochanard, P; McNear, C; Brachmann, SM; Duke-Cohan, JS; Garraway, LA; Sellers, WR,期刊：Molecular and Cellular Biology, 页码：5377-5388 , 文章类型： Article，,卷期：2009年29-19]
- The lipid phosphatase PTEN functions as a tumor suppressor by dephosphorylating the D3 position of phosphoinositide-3,4,5-trisphosphate, thereby negatively regulating the phosphoinositide 3-kinase (PI3K)/AKT signaling pa...
- MicroRNA-125b Promotes Neuronal Differentiation in Human Cells by Repressing Multiple Targets
[作者：Le, MTN; Xie, HM; Zhou, BY; Chia, PH; Rizk, P; Um, M; Udolph, G; Yang, H; Lim, B; Lodish, HF,期刊：Molecular and Cellular Biology, 页码：5290-5305 , 文章类型： Article，,卷期：2009年29-19]
- MicroRNAs (miRNAs) are a class of small noncoding RNAs that regulate gene expression at the posttranscriptional level. Research on miRNAs has highlighted their importance in neural development, but the specific functions...
- The E3 Ubiquitin Ligase TEB4 Mediates Degradation of Type 2 Iodothyronine Deiodinase
[作者：Zavacki, AM; Drigo, RAE; Freitas, BCG; Chung, M; Harney, JW; Egri, P; Wittmann, G; Fekete, C; Gereben, B; Bianco, AC,期刊：Molecular and Cellular Biology, 页码：5339-5347 , 文章类型： Article，,卷期：2009年29-19]
- The endoplasmic reticulum resident thyroid hormone-activating type 2 deiodinase (D2) is inactivated by ubiquitination via the hedgehog-inducible WSB-1. Ubiquitinated D2 can then be subsequently taken up by the proteasoma...
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