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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共19条记录   Dual Nature of Translational Control by Regulatory BC RNAs [作者：Eom, T; Berardi, V; Zhong, J; Risuleo, G; Tiedge, H,期刊：Molecular and Cellular Biology, 页码：4538-4549 , 文章类型： Article，,卷期：2011年31-22] In higher eukaryotes, increasing evidence suggests, gene expression is to a large degree controlled by RNA. Regulatory RNAs have been implicated in the management of neuronal function and plasticity in mammalian brains. ... SCIMP, a Transmembrane Adaptor Protein Involved in Major Histocompatibility Complex Class II Signaling [作者：Draber, P; Vonkova, I; Stepanek, O; Hrdinka, M; Kucova, M; Skopcova, T; Otahal, P; Angelisova, P; Horejsi, V; Yeung, M; Weiss, A; Brdicka, T,期刊：Molecular and Cellular Biology, 页码：4550-4562 , 文章类型： Article，,卷期：2011年31-22] Formation of the immunological synapse between an antigen-presenting cell (APC) and a T cell leads to signal generation in both cells involved. In T cells, the lipid raft-associated transmembrane adaptor protein LAT play... Gab2 Promotes Colony-Stimulating Factor 1-Regulated Macrophage Expansion via Alternate Effectors at Different Stages of Development [作者：Lee, AW; Mao, YW; Penninger, JM; Yu, SJ,期刊：Molecular and Cellular Biology, 页码：4563-4581 , 文章类型： Article，,卷期：2011年31-22] Colony-stimulating factor 1 (CSF-1) receptor (CSF-1R, or macrophage CSF receptor [M-CSFR]) is the primary regulator of the proliferation, survival, and differentiation of mononuclear phagocytes (MNPs), but the critical C... The Drosophila javelin Gene Encodes a Novel Actin-Associated Protein Required for Actin Assembly in the Bristle [作者：Shapira, S; Bakhrat, A; Bitan, A; Abdu, U,期刊：Molecular and Cellular Biology, 页码：4582-4592 , 文章类型： Article，,卷期：2011年31-22] The Drosophila melanogaster bristle is a highly polarized cell that builds specialized cytoskeletal structures. Whereas actin is required for increasing bristle length, microtubules are essential for bristle axial growth... Distinct Functions of Sox2 Control Self-Renewal and Differentiation in the Osteoblast Lineage [作者：Seo, E; Basu-Roy, U; Zavadil, J; Basilico, C; Mansukhani, A,期刊：Molecular and Cellular Biology, 页码：4593-4608 , 文章类型： Article，,卷期：2011年31-22] The transcription factor Sox2 is a key player in the maintenance of pluripotency and "stemness." We have previously shown that Sox2 maintains self-renewal in the osteoblast lineage while inhibiting differentiation (U. Ba... Gata-3 Negatively Regulates the Tumor-Initiating Capacity of Mammary Luminal Progenitor Cells and Targets the Putative Tumor Suppressor Caspase-14 [作者：Asselin-Labat, ML; Sutherland, KD; Vaillant, F; Gyorki, DE; Wu, D; Holroyd, S; Breslin, K; Ward, T; Shi, W; Bath, ML; Deb, S; Fox, SB; Smyth, GK; Lindeman, GJ; Visvader, JE,期刊：Molecular and Cellular Biology, 页码：4609-4622 , 文章类型： Article，,卷期：2011年31-22] The transcription factor Gata-3 is a definitive marker of luminal breast cancers and a key regulator of mammary morphogenesis. Here we have explored a role for Gata-3 in tumor initiation and the underlying cellular mecha... Nucleosome Disruption by DNA Ligase III-XRCC1 Promotes Efficient Base Excision Repair [作者：Odell, ID; Barbour, JE; Murphy, DL; Della-Maria, JA; Sweasy, JB; Tomkinson, AE; Wallace, SS; Pederson, DS,期刊：Molecular and Cellular Biology, 页码：4623-4632 , 文章类型： Article，,卷期：2011年31-22] Each day, approximately 20,000 oxidative lesions form in the DNA of every nucleated human cell. The base excision repair (BER) enzymes that repair these lesions must function in a chromatin milieu. We have determined tha... Differential Role of Nkx2-5 in Activation of the Atrial Natriuretic Factor Gene in the Developing versus Failing Heart [作者：Warren, SA; Terada, R; Briggs, LE; Cole-Jeffrey, CT; Chien, WM; Seki, T; Weinberg, EO; Yang, TP; Chin, MT; Bungert, J; Kasahara, H,期刊：Molecular and Cellular Biology, 页码：4633-4645 , 文章类型： Article，,卷期：2011年31-22] Atrial natriuretic factor (ANF) is abundantly expressed in atrial cardiomyocytes throughout ontogeny and in ventricular cardiomyocytes in the developing heart. However, during cardiac failure and hypertrophy, ANF express... Contribution of Casein Kinase 2 and Spleen Tyrosine Kinase to CFTR Trafficking and Protein Kinase A-Induced Activity [作者：Luz, S; Kongsuphol, P; Mendes, AI; Romeiras, F; Sousa, M; Schreiber, R; Matos, P; Jordan, P; Mehta, A; Amaral, MD; Kunzelmann, K; Farinha, CM,期刊：Molecular and Cellular Biology, 页码：4392-4404 , 文章类型： Article，,卷期：2011年31-22] Previously, the pleiotropic "master kinase" casein kinase 2 (CK2) was shown to interact with CFTR, the protein responsible for cystic fibrosis (CF). Moreover, CK2 inhibition abolished CFTR conductance in cell-attached me... Stress-Stimulated Mitogen-Activated Protein Kinases Control the Stability and Activity of the Cdt1 DNA Replication Licensing Factor [作者：Chandrasekaran, S; Tan, TX; Hall, JR; Cook, JG,期刊：Molecular and Cellular Biology, 页码：4405-4416 , 文章类型： Article，,卷期：2011年31-22] DNA replication is tightly coordinated both with cell cycle cues and with responses to extracellular signals to maintain genome stability. We discovered that human Cdt1, an essential origin licensing protein whose activi... A Novel Role for hSMG-1 in Stress Granule Formation [作者：Brown, JAL; Roberts, TL; Richards, R; Woods, R; Birrell, G; Lim, YC; Ohno, S; Yamashita, A; Abraham, RT; Gueven, N; Lavin, MF,期刊：Molecular and Cellular Biology, 页码：4417-4429 , 文章类型： Article，,卷期：2011年31-22] hSMG-1 is a member of the phosphoinositide 3 kinase-like kinase (PIKK) family with established roles in nonsense-mediated decay (NMD) of mRNA containing premature termination codons and in genotoxic stress responses to D... The Aarskog-Scott Syndrome Protein Fgd1 Regulates Podosome Formation and Extracellular Matrix Remodeling in Transforming Growth Factor beta-Stimulated Aortic Endothelial Cells [作者：Daubon, T; Buccione, R; Genot, E,期刊：Molecular and Cellular Biology, 页码：4430-4441 , 文章类型： Article，,卷期：2011年31-22] Podosomes are dynamic actin-rich adhesion plasma membrane microdomains endowed with extracellular matrix-degrading activities. In aortic endothelial cells, podosomes are induced by transforming growth factor beta (TGF-be... G Protein-Coupled Receptor Signaling and Sphingosine-1-Phosphate Play a Phylogenetically Conserved Role in Endocrine Pancreas Morphogenesis [作者：Serafimidis, I; Heximer, S; Beis, D; Gavalas, A,期刊：Molecular and Cellular Biology, 页码：4442-4453 , 文章类型： Article，,卷期：2011年31-22] During development pancreatic endocrine cells migrate in a coordinated fashion. This migration is necessary to form fully functional islets, but the mechanisms involved remain unknown. Therapeutic strategies to restore b... ATP-Dependent Chromatin Remodeling Factors Tune S Phase Checkpoint Activity [作者：Au, TJ; Rodriguez, J; Vincent, JA; Tsukiyama, T,期刊：Molecular and Cellular Biology, 页码：4454-4463 , 文章类型： Article，,卷期：2011年31-22] The S phase checkpoint response slows down replication in the presence of replication stress such that replication can resume normally once conditions are favorable. Both proper activation and deactivation of the checkpo... TopBP1 Mediates Mutant p53 Gain of Function through NF-Y and p63/p73 [作者：Liu, K; Ling, SY; Lin, WC,期刊：Molecular and Cellular Biology, 页码：4464-4481 , 文章类型： Article，,卷期：2011年31-22] Nearly half of human cancers harbor p53 mutations, which can promote cancerous growth, metastasis, and resistance to therapy. The gain of function of mutant p53 is partly mediated by its ability to form a complex with NF... Requirement of rRNA Methylation for 80S Ribosome Assembly on a Cohort of Cellular Internal Ribosome Entry Sites [作者：Basu, A; Das, P; Chaudhuri, S; Bevilacqua, E; Andrews, J; Barik, S; Hatzoglou, M; Komar, AA; Mazumder, B,期刊：Molecular and Cellular Biology, 页码：4482-4499 , 文章类型： Article，,卷期：2011年31-22] Protein syntheses mediated by cellular and viral internal ribosome entry sites (IRESs) are believed to have many features in common. Distinct mechanisms for ribosome recruitment and preinitiation complex assembly between...