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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共11条记录   Bub1 and BubR1: at the Interface between Chromosome Attachment and the Spindle Checkpoint [作者：Elowe, S,期刊：Molecular and Cellular Biology, 页码：3085-3093 , 文章类型： Review，,卷期：2011年31-15] The spindle checkpoint ensures genome fidelity by temporarily halting chromosome segregation and the ensuing mitotic exit until the last kinetochore is productively attached to the mitotic spindle. At the interface betwe... Histone H3 Lysine 4 Hypermethylation Prevents Aberrant Nucleosome Remodeling at the PHO5 Promoter [作者：Wang, SS; Zhou, BO; Zhou, JQ,期刊：Molecular and Cellular Biology, 页码：3171-3181 , 文章类型： Article，,卷期：2011年31-15] Recent studies have highlighted the histone H3K4 methylation (H3K4me)-dependent transcriptional repression in Saccharomyces cerevisiae; however, the underlying mechanism remains inexplicit. Here, we report that H3K4me in... Inhibition of Protein Degradation Induces Apoptosis through a Microtubule-Associated Protein 1 Light Chain 3-Mediated Activation of Caspase-8 at Intracellular Membranes [作者：Pan, JA; Ullman, E; Dou, ZX; Zong, WX,期刊：Molecular and Cellular Biology, 页码：3158-3170 , 文章类型： Article，,卷期：2011年31-15] The accumulation of damaged or misfolded proteins, if unresolved, can lead to a detrimental consequence within cells termed proteotoxicity. Since cancerous cells often display elevated protein synthesis and by-product di... Nonallelic Transcriptional Roles of CTCF and Cohesins at Imprinted Loci [作者：Lin, S; Ferguson-Smith, AC; Schultz, RM; Bartolomei, MS,期刊：Molecular and Cellular Biology, 页码：3094-3104 , 文章类型： Article，,卷期：2011年31-15] The cohesin complex holds sister chromatids together and is essential for chromosome segregation. Recently, cohesins have been implicated in transcriptional regulation and insulation through genome-wide colocalization wi... Importin alpha-Mediated Nuclear Import of Cytoplasmic Poly(A) Binding Protein Occurs as a Direct Consequence of Cytoplasmic mRNA Depletion [作者：Kumar, GR; Shum, L; Glaunsinger, BA,期刊：Molecular and Cellular Biology, 页码：3113-3125 , 文章类型： Article，,卷期：2011年31-15] Recent studies have found the cytoplasmic poly(A) binding protein (PABPC) to have opposing effects on gene expression when concentrated in the cytoplasm versus in the nucleus. PABPC is predominantly cytoplasmic at steady... miR-29a and miR-29b Contribute to Pancreatic beta-Cell-Specific Silencing of Monocarboxylate Transporter 1 (Mct1) [作者：Pullen, TJ; Xavier, GD; Kelsey, G; Rutter, GA,期刊：Molecular and Cellular Biology, 页码：3182-3194 , 文章类型： Article，,卷期：2011年31-15] In pancreatic beta cells, elevated glucose concentrations stimulate mitochondrial oxidative metabolism to raise intracellular ATP/ADP levels, prompting insulin secretion. Unusually low levels of expression of genes encod... AMPK -> ULK1 -> Autophagy [作者：Roach, PJ,期刊：Molecular and Cellular Biology, 页码：3082-3084 , 文章类型： Editorial Material，,卷期：2011年31-15] Selective Ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G Ubiquitin-Conjugating Enzymes via the CRL4(Cdt2) Ubiquitin Ligase Complex [作者：Shibata, E; Abbas, T; Huang, XH; Wohlschlegel, JA; Dutta, A,期刊：Molecular and Cellular Biology, 页码：3136-3145 , 文章类型： Article，,卷期：2011年31-15] CRL4(Cdt2) is a cullin-based E3 ubiquitin ligase that promotes the ubiquitin-dependent proteolysis of various substrates implicated in the control of cell cycle and various DNA metabolic processes such as DNA replication... Sequestration of Toxic Oligomers by HspB1 as a Cytoprotective Mechanism [作者：Ojha, J; Masilamoni, G; Dunlap, D; Udoff, RA; Cashikar, AG,期刊：Molecular and Cellular Biology, 页码：3146-3157 , 文章类型： Article，,卷期：2011年31-15] Small heat shock proteins (sHsps) are molecular chaperones that protect cells from cytotoxic effects of protein misfolding and aggregation. HspB1, an sHsp commonly associated with senile plaques in Alzheimer's disease (A... Topoisomerase 1 and Single-Strand Break Repair Modulate Transcription-Induced CAG Repeat Contraction in Human Cells [作者：Hubert, L; Lin, YF; Dion, V; Wilson, JH,期刊：Molecular and Cellular Biology, 页码：3105-3112 , 文章类型： Article，,卷期：2011年31-15] Expanded trinucleotide repeats are responsible for a number of neurodegenerative diseases, such as Huntington disease and myotonic dystrophy type 1. The mechanisms that underlie repeat instability in the germ line and in... Ubp8 and SAGA Regulate Snf1 AMP Kinase Activity [作者：Wilson, MA; Koutelou, E; Hirsch, C; Akdemir, K; Schibler, A; Barton, MC; Dent, SYR,期刊：Molecular and Cellular Biology, 页码：3126-3135 , 文章类型： Article，,卷期：2011年31-15] Posttranslational modifications of histone proteins play important roles in the modulation of gene expression. The Saccharomyces cerevisiae (yeast) 2-MDa SAGA (Spt-Ada-Gcn5) complex, a well-studied multisubunit histone m...