- PHF10 Is Required for Cell Proliferation in Normal and SV40-Immortalized Human Fibroblast Cells
[作者:Banga, SS; Peng, L; Dasgupta, T; Palejwala, V; Ozer, HL,期刊:Cytogenetic and Genome Research, 页码:227-242 , 文章类型: Article,,卷期:2009年126-3]
- Normal human diploid fibroblasts have limited life span in culture and undergo replicative senescence after 50-60 population doublings. On the contrary, cancer cells typically divide indefinitely and are immortal. Expres...
- Ccdc33, a Predominantly Testis-Expressed Gene, Encodes a Putative Peroxisomal Protein
[作者:Kaczmarek, K; Niedzialkowska, E; Studencka, M; Schulz, Y; Grzmil, P,期刊:Cytogenetic and Genome Research, 页码:243-252 , 文章类型: Article,,卷期:2009年126-3]
- Many genes crucial for male fertility are often predominantly or exclusively expressed in male germ cells. The analysis of mouse models has demonstrated the functional importance of peroxisomes in spermatogenesis. The CC...
- A Highly Conserved Pericentromeric Domain in Human and Gorilla Chromosomes
[作者:Pita, M; Gosalvez, J; Gosalvez, A; Nieddu, M; Lopez-Fernandez, C; Mezzanotte, R,期刊:Cytogenetic and Genome Research, 页码:253-258 , 文章类型: Article,,卷期:2009年126-3]
- Significant similarity between human and gorilla genomes has been found in all chromosome arms, but not in centromeres, using whole-comparative genomic hybridization (W-CGH). In human chromosomes, centromeric regions, ge...
- Existence of Pink1 Antisense RNAs in Mouse and Their Localization
[作者:Chiba, M; Kiyosawa, H; Hiraiwa, N; Ohkohchi, N; Yasue, H,期刊:Cytogenetic and Genome Research, 页码:259-270 , 文章类型: Article,,卷期:2009年126-3]
- PTEN-induced kinase 1 (PINK1), which is identified as the gene transactivated by the tumor suppressor PTEN, has been found to be one of the causative genes in Parkinson's disease (PD). In order to understand PD, rodent m...
- A Cytogenetic Study of Breeding Boars in Canada
[作者:Quach, TA; Villagomez, DAF; Coppola, G; Pinton, A; Hart, EJ; Reyes, ER; Basrur, PK; King, WA,期刊:Cytogenetic and Genome Research, 页码:271-280 , 文章类型: Article,,卷期:2009年126-3]
- Chromosome abnormalities are well known for their negative impact on the reproductive performance of carriers. Such abnormalities could have severe effect on animal industries which rely heavily on efficient reproduction...
- Cross-Species Chromosome Painting Corroborates Microchromosome Fusion during Karyotype Evolution of Birds
[作者:Hansmann, T; Nanda, I; Volobouev, V; Yang, F; Schartl, M; Haaf, T; Schmid, M,期刊:Cytogenetic and Genome Research, 页码:281-304 , 文章类型: Article,,卷期:2009年126-3]
- The stone curlew, also known as thick-knee (Burhinus oedicnemus, BOE), represents a phylogenetically young species of the shorebirds (Charadriiformes) that exhibits one of the most atypical genome organizations known wit...
- Cytogenetic and Array-CGH Characterization of a Complex de novo Rearrangement Involving Duplication and Deletion of 9p and Clinical Findings in a 4-Month-Old Female
[作者:Hulick, PJ; Noonan, KM; Kulkarni, S; Donovan, DJ; Listewnik, M; Ihm, C; Stoler, JM; Weremowicz, S,期刊:Cytogenetic and Genome Research, 页码:305-312 , 文章类型: Article,,卷期:2009年126-3]
- Approximately 15 patients with partial trisomy 9p involving de novo duplications have been previously described. Here, we present clinical, cytogenetic, FISH and aCGH findings in a patient with a de novo complex rearrang...
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