- A Synonymous Single Nucleotide Polymorphism in Delta F508 CFTR Alters the Secondary Structure of the mRNA and the Expression of the Mutant Protein
[作者:Bartoszewski, RA; Jablonsky, M; Bartoszewska, S; Stevenson, L; Dai, Q; Kappes, J; Collawn, JF; Bebok, Z,期刊:Journal of Biological Chemistry, 页码:28741-28748 , 文章类型: Article,,卷期:2010年285-37]
- Recent advances in our understanding of translational dynamics indicate that codon usage and mRNA secondary structure influence translation and protein folding. The most frequent cause of cystic fibrosis (CF) is the dele...
- Identification of Eukaryotic and Prokaryotic Methylthiotransferase for Biosynthesis of 2-Methylthio-N-6-threonylcarbamoyladenosine in tRNA
[作者:Arragain, S; Handelman, SK; Forouhar, F; Wei, FY; Tomizawa, K; Hunt, JF; Douki, T; Fontecave, M; Mulliez, E; Atta, M,期刊:Journal of Biological Chemistry, 页码:28425-28433 , 文章类型: Article,,卷期:2010年285-37]
Bacterial and eukaryotic transfer RNAs have been shown to contain hypermodified adenosine, 2-methylthio-N-6-threonylcarbamoyladenosine, at position 37 (A(37)) adjacent to the 3'-end of the anticodon, which is essentia...
- Bcl-2 and Bax Interact via the BH1-3 Groove-BH3 Motif Interface and a Novel Interface Involving the BH4 Motif
[作者:Ding, JZ; Zhang, Z; Roberts, GJ; Falcone, M; Miao, YW; Shao, YL; Zhang, XJC; Andrews, DW; Lin, JL,期刊:Journal of Biological Chemistry, 页码:28749-28763 , 文章类型: Article,,卷期:2010年285-37]
- The interaction of Bcl-2 family proteins at the mitochondrial outer membrane controls membrane permeability and thereby the apoptotic program. The anti-apoptotic protein Bcl-2 binds to the pro-apoptotic protein Bax to pr...
- Role of Transmembrane Domain 8 in Substrate Selectivity and Translocation of SteT, a Member of the L-Amino Acid Transporter (LAT) Family
[作者:Bartoccioni, P; del Rio, C; Ratera, M; Kowalczyk, L; Baldwin, JM; Zorzano, A; Quick, M; Baldwin, SA; Vazquez-Ibar, JL; Palacin, M,期刊:Journal of Biological Chemistry, 页码:28764-28776 , 文章类型: Article,,卷期:2010年285-37]
- System L-amino acid transporters (LAT) belong to the amino acid, polyamine, and organic cation superfamily of transporters and include the light subunits of heteromeric amino acid transporters and prokaryotic homologues....
- Functional Diversity in Fungal Fatty Acid Synthesis THE FIRST ACETYLENASE FROM THE PACIFIC GOLDEN CHANTERELLE, CANTHARELLUS FORMOSUS
[作者:Blacklock, BJ; Scheffler, BE; Shepard, MR; Jayasuriya, N; Minto, RE,期刊:Journal of Biological Chemistry, 页码:28442-28449 , 文章类型: Article,,卷期:2010年285-37]
- Acetylenic specialized metabolites containing one or more carbon-carbon triple bonds are widespread, being found in fungi, vascular and lower plants, marine sponges and algae, and insects. Plants, moss, and most recently...
- Characterization of C1q in Teleosts INSIGHT INTO THE MOLECULAR AND FUNCTIONAL EVOLUTION OF C1q FAMILY AND CLASSICAL PATHWAY
[作者:Hu, YL; Pan, XM; Xiang, LX; Shao, JZ,期刊:Journal of Biological Chemistry, 页码:28777-28786 , 文章类型: Article,,卷期:2010年285-37]
- C1qs are key components of the classical complement pathway. They have been well documented in human and mammals, but little is known about their molecular and functional characteristics in fish. In the present study, fu...
- Paxillin Regulates Androgen- and Epidermal Growth Factor-induced MAPK Signaling and Cell Proliferation in Prostate Cancer Cells
[作者:Sen, A; O'Malley, K; Wang, Z; Raj, GV; DeFranco, DB; Hammes, SR,期刊:Journal of Biological Chemistry, 页码:28787-28795 , 文章类型: Article,,卷期:2010年285-37]
- Although transcriptional effects of androgens have been extensively studied, mechanisms regulating transcription-independent (nongenomic) androgen actions are poorly understood. Previously, we have shown that paxillin, a...
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