- Erbium : YAG laser enhances transdermal peptide delivery and skin vaccination
[作者:Lee, WR; Pan, TL; Wang, PW; Zhuo, RZ; Huang, CM; Fang, JY,期刊:Journal of controlled release, 页码:200-208 , 文章类型: Article,,卷期:2008年128-3]
- Transdermal delivery of peptides and the related vaccines is attractive for treatment and prevention of diseases. However, this delivery method is limited by the low permeability of the stratum corneum (SC). The objectiv...
- Preparation and characterization of PE38KDEL-loaded anti-HER2 nanoparticles for targeted cancer therapy
[作者:Chen, HW; Gao, J; Lu, Y; Kou, G; Zhang, H; Fan, L; Sun, ZG; Guo, YJ; Zhong, YQ,期刊:Journal of controlled release, 页码:209-216 , 文章类型: Article,,卷期:2008年128-3]
- The clinical use of immunotoxins is severely limited by nonspecific toxicity. To overcome this limitation, PE38KDEL was used as a model protein toxin to prepare PE38KDEL-loaded poly(lactic-co-glycolic acid) (PLGA) antibo...
- A new atherosclerotic lesion probe based on hydrophobically modified chitosan nanoparticles functionalized by the atherosclerotic plaque targeted peptides
[作者:Park, Y; Hong, HY; Moon, HJ; Lee, BH; Kim, IS; Kwon, IC; Rhee, I,期刊:Journal of controlled release, 页码:217-223 , 文章类型: Article,,卷期:2008年128-3]
- We developed a new imaging probe for atherosclerotic lesion imaging by chemically conjugating an atherosclerotic plaque-homing peptide (termed the AP peptide) to hydrophobically modified glycol chitosan (HGC) nanoparticl...
- Modular drug transporters with diphtheria toxin translocation domain form edged holes in lipid membranes
[作者:Khramtsov, YV; Rokitskaya, TI; Rosenkranz, AA; Trusov, GA; Gnuchev, NV; Antonenko, YN; Sobolev, AS,期刊:Journal of controlled release, 页码:241-247 , 文章类型: Article,,卷期:2008年128-3]
- Modular/chimeric recombinant drugs or drug transporters usually contain a special translocation domain from bacterial toxins, e.g. diphtheria toxin, as a module enabling escape of the chimeric molecules from acidifying e...
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