- Elevated lung cancer risk is associated with deficiencies in cell cycle checkpoints: genotype and phenotype analyses from a case-control study
[作者:Zheng, YL; Kosti, O; Loffredo, CA; Bowman, E; Mechanic, L; Perlmutter, D; Jones, R; Shields, PG; Harris, CC,期刊:International Journal of Cancer, 页码:2199-2210 , 文章类型: Article,,卷期:2010年126-9]
- Cell cycle checkpoints play critical roles in the maintenance of genomic integrity and inactivation of checkpoint genes are frequently perturbed in most cancers. In a case-control study of 299 non-small cell lung cancer ...
- The influence of a period of caloric restriction due to the Dutch Famine on breast density
[作者:Haars, G; van Gils, CH; Elias, SG; Lokate, M; van Noord, PAH; Peeters, PHM,期刊:International Journal of Cancer, 页码:2211-2215 , 文章类型: Article,,卷期:2010年126-9]
- Recently, we showed that short, intense caloric restriction due to the Dutch famine increased breast cancer risk in women and influenced the hormonal- and IGF-system. These systems may also affect breast density, which i...
- Targeted knockdown of Bcl2 in tumor cells using a synthetic TRAIL 3 '-UTR microRNA
[作者:Zhang, JJ; Huang, SL; Zhang, H; Wang, HB; Guo, HY; Qian, GX; Fan, XQ; Lu, J; Hoffman, AR; Hu, JF; Ge, SF,期刊:International Journal of Cancer, 页码:2229-2239 , 文章类型: Article,,卷期:2010年126-9]
- Targeting tumor-related overexpression of anti-apoptotic Bcl2 protein by RNAi has been suggested as a potential treatment for cancer. However, the stability of RNAi and its delivery are still major obstacles to the clini...
- Merkel cell carcinoma subgroups by Merkel cell polyomavirus DNA relative abundance and oncogene expression
[作者:Bhatia, K; Goedert, JJ; Modali, R; Preiss, L; Ayers, LW,期刊:International Journal of Cancer, 页码:2240-2246 , 文章类型: Article,,卷期:2010年126-9]
- Merkel cell polyomavirus (MCPyV) was recently discovered in Merkel cell carcinoma (MCC), a clinically and pathologically heterogeneous malignancy of dermal neuroendocrine cells. To investigate this heterogeneity, we deve...
- The polyamine metabolism genes ornithine decarboxylase and antizyme 2 predict aggressive behavior in neuroblastomas with and without MYCN amplification
[作者:Geerts, D; Koster, J; Albert, D; Koomoa, DLT; Feith, DJ; Pegg, AE; Volckmann, R; Caron, H; Versteeg, R; Bachmann, AS,期刊:International Journal of Cancer, 页码:2012-2024 , 文章类型: Article,,卷期:2010年126-9]
- High polyamine (PA) levels and ornithine decarboxylase (ODC) overexpression are well-known phenomena in many aggressive cancer types. We analyzed the expression of ODC and ODC-activity regulating genes antizymes 1-3 (OAZ...
- Significance of Plk1 regulation by miR-100 in human nasopharyngeal cancer
[作者:Shi, W; Alajez, NM; Bastianutto, C; Hui, ABY; Mocanu, JD; Ito, E; Busson, P; Lo, KW; Ng, R; Waldron, J; O'Sullivan, B; Liu, FF,期刊:International Journal of Cancer, 页码:2036-2048 , 文章类型: Article,,卷期:2010年126-9]
- Polo-like kinase 1 (Plkl) is a critical regulator of many stages of mitosis; increasing evidence indicates that Plk1 overexpression correlates with poor clinical outcome, yet its mechanism of regulation remains unknown. ...
- Cancer stem/progenitor cells are highly enriched in CD133(+)CD44(+) population in hepatocellular carcinoma
[作者:Zhu, Z; Hao, XF; Yan, MX; Yao, M; Ge, C; Gu, JR; Li, JJ,期刊:International Journal of Cancer, 页码:2067-2078 , 文章类型: Article,,卷期:2010年126-9]
- Both our previous study and other reports have suggested that CD133, originally classified as a hematopoietic stem cell marker, could be used for enrichment of cancer stem cells (CSCs) in human hepatocellular carcinoma (...
- Hospicells (ascites-derived stromal cells) promote tumorigenicity and angiogenesis
[作者:Pasquet, M; Golzio, M; Mery, E; Rafii, A; Benabbou, N; Mirshahi, P; Hennebelle, I; Bourin, P; Allal, B; Teissie, J; Mirshahi, M; Couderc, B,期刊:International Journal of Cancer, 页码:2090-2101 , 文章类型: Article,,卷期:2010年126-9]
- The microenvironment is known to play a dominant role in cancer progression. Cells closely associated with tumoral cells, named hospicells, have been recently isolated from the ascites of ovarian cancer patients. Whilst ...
|