- Polymorphisms in genes of the steroid receptor superfamily modify postmenopausal breast cancer risk associated with menopausal hormone therapy
[作者:Abbas, S; Beckmann, L; Chang-Claude, J; Hein, R; Kropp, S; Parthimos, M; Dunnebier, T; Hamann, U; Brors, B; Eils, R; Zapatka, M; Brauch, H; Justenhoven, C; Flesch-Janys, D; Braendle, W; Bruning, T; Pesch, B; Spickenheuer, A; Baisch, C; Ko, YD,期刊:International Journal of Cancer, 页码:2935-2946 , 文章类型: Article,,卷期:2010年126-12]
- Menopausal hormone therapy (HT) is associated with increased breast cancer risk among postmenopausal women. Nuclear receptors are involved in steroid hormone- and xenobiotic-mediated signal transduction playing a crucial...
- Prospective study of body mass index, physical activity and thyroid cancer
[作者:Leitzmann, MF; Brenner, A; Moore, SC; Koebnick, C; Park, Y; Hollenbeck, A; Schatzkin, A; Ron, E,期刊:International Journal of Cancer, 页码:2947-2956 , 文章类型: Article,,卷期:2010年126-12]
- Increased body size and physical inactivity are positively related to risk of several cancers, but only few epidemiologic studies have investigated body-mass index (BMI) and physical activity in relation to thyroid cance...
- Can physical activity modulate pancreatic cancer risk? a systematic review and meta-analysis
[作者:O'Rorke, MA; Cantwell, MM; Cardwell, CR; Mulholland, HG; Murray, LJ,期刊:International Journal of Cancer, 页码:2957-2968 , 文章类型: Article,,卷期:2010年126-12]
- Numerous epidemiological studies have examined the association between physical activity and pancreatic cancer; however, findings from individual cohorts have largely not corroborated a protective effect. Among other pla...
- Establishment of the 1st World Health Organization international standards for human papillomavirus Type 16 DNA and Type 18 DNA
[作者:Wilkinson, DE; Baylis, SA; Padley, D; Heath, AB; Ferguson, M; Pagliusi, SR; Quint, WG; Wheeler, CM,期刊:International Journal of Cancer, 页码:2969-2983 , 文章类型: Article,,卷期:2010年126-12]
- A World Health Organization collaborative study was conducted to evaluate candidate international standards for human papillomavirus (HPV) Type 16 DNA (NIBSC code 06/202) and HPV Type 18 DNA (NIBSC code 06/206) for use i...
- Risk of differentiated thyroid cancer in relation to adult weight, height and body shape over life: the French E3N cohort
[作者:Clavel-Chapelon, F; Guillas, G; Tondeur, L; Kernaleguen, C; Boutron-Ruault, MC,期刊:International Journal of Cancer, 页码:2984-2990 , 文章类型: Article,,卷期:2010年126-12]
- The increasing incidence rate of thyroid cancer warrants investigation of potentially modifiable factors, especially overweightness. Few prospective studies have investigated anthropometry from childhood to adulthood in ...
- Quantitative detection of Merkel cell virus in human tissues and possible mode of transmission
[作者:Loyo, M; Guerrero-Preston, R; Brait, M; Hoque, MO; Chuang, A; Kim, MS; Sharma, R; Liegeois, NJ; Koch, WM; Califano, JA; Westra, WH; Sidransky, D,期刊:International Journal of Cancer, 页码:2991-2996 , 文章类型: Article,,卷期:2010年126-12]
- Merkel Cell Virus (MCV) is a newly discovered polyomavirus, recently found in a rare skin cancer, Merkel cell carcinoma (MCC). However, MCV has also been detected in some normal tissue samples. We tested and compared the...
- Therapy for minimal residual tumor disease: beta-galactosylceramide inhibits the growth of recurrent HPV16-associated neoplasms after surgery and chemotherapy
[作者:Simova, J; Indrova, M; Bieblova, J; Mikyskova, R; Bubenik, J; Reinis, M,期刊:International Journal of Cancer, 页码:2997-3004 , 文章类型: Article,,卷期:2010年126-12]
- Natural killer T (NKT) cells are potent modulators of antitumor immunity. Their protective effects can be achieved upon their activation by glycolipid ligands presented in the context of the CD1d molecule. These CD1d-bin...
- CHEK2 mutations and HNPCC-related colorectal cancer
[作者:Suchy, J; Cybulski, C; Wokolorczyk, D; Oszurek, O; Gorski, B; Debniak, T; Jakubowska, A; Gronwald, J; Huzarski, T; Byrski, T; Dziuba, I; Gogacz, M; Wisniowski, R; Wandzel, P; Banaszkiewicz, Z; Kurzawski, G; Kladny, J; Narod, SA; Lubinski, J,期刊:International Journal of Cancer, 页码:3005-3009 , 文章类型: Article,,卷期:2010年126-12]
- Recently, the 1100delC variant of cell cycle checkpoint kinase 2 (CHEK2) has been reported to confer a colorectal cancer risk in hereditary non-polyposis-colorectal cancer (HNPCC) and HNPCC-related families in the Nether...
- Arginine deprivation and argininosuccinate synthetase expression in the treatment of cancer
[作者:Delage, B; Fennell, DA; Nicholson, L; McNeish, I; Lemoine, NR; Crook, T; Szlosarek, PW,期刊:International Journal of Cancer, 页码:2762-2772 , 文章类型: Review,,卷期:2010年126-12]
- Arginine, a semi-essential amino acid in humans, is critical for the growth of human cancers, particularly those marked by de novo chemoresistance and a poor clinical outcome. In addition to protein synthesis, arginine i...
- Metronomic administration of the drug GMX1777, a cellular NAD synthesis inhibitor, results in neuroblastoma regression and vessel maturation without inducing drug resistance
[作者:Fuchs, D; Rodriguez, A; Eriksson, S; Christofferson, R; Sundberg, C; Azarbayjani, F,期刊:International Journal of Cancer, 页码:2773-2789 , 文章类型: Article,,卷期:2010年126-12]
- High-risk neuroblastoma is a rapidly growing tumor with a survival rate below 50%. A new treatment strategy is to administer chemotherapeutic drugs metronomically, i.e., at lower doses and frequent intervals. The aim of ...
- EWS/Fli-1 chimeric fusion gene upregulates vascular endothelial growth factor-A
[作者:Nagano, A; Ohno, T; Shimizu, K; Hara, A; Yamamoto, T; Kawai, G; Saitou, M; Takigami, I; Matsuhashi, A; Yamada, K; Takei, Y,期刊:International Journal of Cancer, 页码:2790-2798 , 文章类型: Article,,卷期:2010年126-12]
- Vascular endothelial growth factor (VEGF)-A plays an important role in the pathological angiogenesis that occurs in soft-tissue sarcoma and in about half of Ewing's sarcoma cases, where it is highly overexpressed. EWS/Fl...
- Tumor suppressor function of Rab25 in triple-negative breast cancer
[作者:Cheng, JM; Volk, L; Janaki, DKM; Vyakaranam, S; Ran, S; Rao, KA,期刊:International Journal of Cancer, 页码:2799-2812 , 文章类型: Article,,卷期:2010年126-12]
- Rab proteins are a group of ubiquitously expressed proteins that are responsible for intracellular transport of vesicles. Recent evidence has shown that certain Rab proteins are involved in the pathogenesis of cancer. We...
- Mismatch repair system decreases cell survival by stabilizing the tetraploid G1 arrest in response to SN-38
[作者:Bhonde, MR; Hanski, ML; Stehr, J; Jebautzke, B; Peiro-Jordan, R; Fechner, H; Yokoyama, KK; Lin, WC; Zeitz, M; Hanski, C,期刊:International Journal of Cancer, 页码:2813-2825 , 文章类型: Article,,卷期:2010年126-12]
- The role of the mismatch repair (MMR) system in correcting base base mismatches is well established; its involvement in the response to DNA double strand breaks, however, is less clear. We investigated the influence of t...
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