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文章名     作者     期刊名     摘要     卷     期         如果没有找到您所需要的文献，请点击 ——此处申请     共26条记录   Betulinic acid suppresses STAT3 activation pathway through induction of protein tyrosine phosphatase SHP-1 in human multiple myeloma cells [作者：Pandey, MK; Sung, B; Aggarwal, BB,期刊：International Journal of Cancer, 页码：282-292 , 文章类型： Article，,卷期：2010年127-2] STAT3 activation has been associated with survival, proliferation and invasion of various human cancers. Whether betulinic acid, a pentacyclic triterpene, can modulate the STAT3 pathway, was investigated in human multipl... Oxidative stress-dependent increase in ICAM-1 expression promotes adhesion of colorectal and pancreatic cancers to the senescent peritoneal mesothelium [作者：Ksiazek, K; Mikula-Pietrasik, J; Catar, R; Dworacki, G; Winckiewicz, M; Frydrychowicz, M; Dragun, D; Staniszewski, R; Jorres, A; Witowski, J,期刊：International Journal of Cancer, 页码：293-303 , 文章类型： Article，,卷期：2010年127-2] Intercellular adhesion molecule-1 (ICAM-1) has been implicated in adhesion of colorectal and pancreatic cancer cells (of the SW480 and PSN-1 line, respectively) to the peritoneal mesothelium. It has been demonstrated tha... Functional characterization of THY1 as a tumor suppressor gene with antiinvasive activity in nasopharyngeal carcinoma [作者：Lung, HL; Cheung, AKL; Cheng, Y; Kwong, FM; Lo, PHY; Law, EWL; Chua, D; Zabarovsky, ER; Wang, N; Tsao, SW; Stanbridge, EJ; Lung, ML,期刊：International Journal of Cancer, 页码：304-312 , 文章类型： Article，,卷期：2010年127-2] THY1 was previously identified as a candidate tumor suppressor gene (TSG) associated with lymph node metastases in nasopharyngeal carcinoma (NPC) through functional studies. It was identified by oligonucleotide microarra... MicroRNA-34a is an important component of PRIMA-1-induced apoptotic network in human lung cancer cells [作者：Duan, WR; Gao, L; Wu, X; Wang, L; Nana-Sinkam, SP; Otterson, GA; Villalona-Calero, MA,期刊：International Journal of Cancer, 页码：313-320 , 文章类型： Article，,卷期：2010年127-2] Restoration of p53 function in tumor cells would be an attractive strategy for lung cancer therapy because p53 mutations are found in more than 50% of lung cancers. The small molecule PRIMA-1 has been shown to restore th... The effects of telomerase inhibition on prostate tumor-initiating cells [作者：Marian, CO; Wright, WE; Shay, JW,期刊：International Journal of Cancer, 页码：321-331 , 文章类型： Article，,卷期：2010年127-2] Prostate cancer is the most common malignancy in men, and patients with metastatic disease have poor outcome even with the most advanced therapeutic approaches. Most cancer therapies target the bulk tumor cells, but may ... Tumor-stromal crosstalk in invasion of oral squamous cell carcinoma: a pivotal role of CCL7 [作者：Jung, DW; Che, ZM; Kim, J; Kim, K; Kim, KY; Williams, D; Kim, J,期刊：International Journal of Cancer, 页码：332-344 , 文章类型： Article，,卷期：2010年127-2] Recent studies have shown that stromal fibroblasts have a more profound influence on the initiation and progression of carcinoma than was previously appreciated. This study aimed at investigating the reciprocal relations... Zoledronic acid protects against osteosarcoma-induced bone destruction but lacks efficacy against pulmonary metastases in a syngeneic rat model [作者：Labrinidis, A; Hay, S; Liapis, V; Findlay, DM; Evdokiou, A,期刊：International Journal of Cancer, 页码：345-354 , 文章类型： Article，,卷期：2010年127-2] Osteosarcoma (OS) is the most common primary malignant tumor of bone in children and adolescents. In spite of successful control of the primary tumor, death from lung metastasis occurs in more than a third of patients. T... High CCND1 amplification identifies a group of poor prognosis women with estrogen receptor positive breast cancer [作者：Roy, PG; Pratt, N; Purdie, CA; Baker, L; Ashfield, A; Quinlan, P; Thompson, AM,期刊：International Journal of Cancer, 页码：355-360 , 文章类型： Article，,卷期：2010年127-2] CCND1 encodes for the cyclin D1 protein involved in G1/S cell cycle transition. In breast cancer the mechanism of CCND1 amplification, relationship between cyclin D1 protein expression and the key clinical markers estrog... Parent of origin effects on age at colorectal cancer diagnosis [作者：Lindor, NM; Rabe, KG; Petersen, GM; Chen, H; Bapat, B; Hopper, J; Young, J; Jenkins, M; Potter, J; Newcomb, P; Templeton, A; LeMarchand, L; Grove, J; Burgio, MR; Haile, R; Green, J; Woods, MO; Seminara, D; Limburg, PJ; Thibodeau, SN,期刊：International Journal of Cancer, 页码：361-366 , 文章类型： Article，,卷期：2010年127-2] Genomic imprinting refers to a parent-of-origin specific effect on gene expression. At least 1% of genes in the human genome are modulated in this manner. We sought evidence for genomic imprinting in colorectal cancer by... Clinicopathological and protein characterization of BRAF- and K-RAS-mutated colorectal cancer and implications for prognosis [作者：Zlobec, I; Bihl, MP; Schwarb, H; Terracciano, L; Lugli, A,期刊：International Journal of Cancer, 页码：367-380 , 文章类型： Article，,卷期：2010年127-2] Recent evidence highlights the potential prognostic and predictive value of BRAF and K-RAS gene alterations in patients with colorectal cancer. However, a comprehensive evaluation of BRAF and K-RAS mutations and their sp... NY-CO-58/KIF2C is overexpressed in a variety of solid tumors and induces frequent T cell responses in patients with colorectal cancer [作者：Gnjatic, S; Cao, YR; Reichelt, U; Yekebas, EF; Nolker, C; Marx, AH; Erbersdobler, A; Nishikawas, H; Hildebrandt, Y; Bartels, K; Horn, C; Stahi, T; Gout, I; Filonenko, V; Ling, KL; Cerundolo, V; Luetkens, T; Ritter, G; Friedrichs, K; Leuwer, R; Hegewisch-Becker, S; Izbicki, JR; Bokemeyer, C; Old, LJ; Atanackovic, D,期刊：International Journal of Cancer, 页码：381-393 , 文章类型： Article，,卷期：2010年127-2] NY-CO-58/KIF2C has been identified as a tumor antigen by screening antibody responses in patients with colorectal cancer. However, expression had not consequently been examined, and nothing was known about its ability to... Expression of microRNA-221 is progressively reduced in aggressive prostate cancer and metastasis and predicts clinical recurrence [作者：Spahn, M; Kneitz, S; Scholz, CJ; Stenger, N; Rudiger, T; Strobel, P; Riedmiller, H; Kneitz, B,期刊：International Journal of Cancer, 页码：394-403 , 文章类型： Article，,卷期：2010年127-2] Emerging evidence shows that microRNAs (miR) are involved in the pathogenesis of a variety of cancers, including prostate carcinoma (PCa). Little information is available regarding miR expression levels in lymph node met... High-throughput detection of nuclear factor-kappaB activity using a sensitive oligo-based chemiluminescent enzyme-linked immunosorbent assay [作者：Bhattacharya, N; Sarno, A; Idler, IS; Fuhrer, M; Zenz, T; Dohner, H; Stilgenbauer, S; Mertens, D,期刊：International Journal of Cancer, 页码：404-411 , 文章类型： Article，,卷期：2010年127-2] Contemporary research on cellular signaling has undergone a shift of focus from qualitative measurements of single signaling pathways to high-throughput quantitation of comprehensive signaling networks. Notably, nuclear ... Radiation-induced leukemia among children aged 0-5 years at the time of the Chernobyl accident [作者：Noshchenko, AG; Bondar, OY; Drozdova, VD,期刊：International Journal of Cancer, 页码：412-426 , 文章类型： Article，,卷期：2010年127-2] This case-control study was conducted to estimate the radiation-induced risk of acute leukemia during the period from 1987 to 1997 among residents 0-5 years of age at the time of the Chernobyl accident in the most radioa... A case-control study of ocular surface squamous neoplasia (OSSN) in Uganda [作者：Waddell, K; Kwehangana, J; Johnston, WT; Lucas, S; Newton, R,期刊：International Journal of Cancer, 页码：427-432 , 文章类型： Article，,卷期：2010年127-2] HIV increases the risk of OSSN. Here we investigate other factors in a case-control study from Uganda with 318 cases (48 CIN I, 66 CIN II, 81 CIN III and 123 with invasive disease) and 762 controls. Initial analyses were... Dietary patterns and gastric cancer in a Portuguese urban population [作者：Bastos, J; Lunet, N; Peleteiro, B; Lopes, C; Barros, H,期刊：International Journal of Cancer, 页码：433-441 , 文章类型： Article，,卷期：2010年127-2] Dietary patterns analysis is a powerful technique to study the relations between diet and cancer. We aimed to quantify the association between dietary patterns and gastric cancer, by location and histological type, accor...