- Downregulation of the Rho GTPase signaling pathway is involved in the microRNA-138-mediated inhibition of cell migration and invasion in tongue squamous cell carcinoma
[作者：Jiang, L; Liu, XQ; Kolokythas, A; Yu, JS; Wang, AX; Heidbreder, CE; Shi, F; Zhou, XF,期刊：International Journal of Cancer, 页码：505-512 , 文章类型： Article，,卷期：2010年127-3]
- Tumor metastasis is the dominant cause of death in cancer patients, including patients with oral tongue squamous cell carcinoma (TSCC). Previously, we reported that reduced miR-138 level is correlated with enhanced metas...
- Effects of antibodies induced by a conjugate vaccine on 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone absorptive transport, metabolism, and proliferation of human lung cells
[作者：De Buck, SS; Schellenberger, MT; Ensch, C; Muller, CP,期刊：International Journal of Cancer, 页码：513-520 , 文章类型： Article，,卷期：2010年127-3]
- One of the most abundant and potent lung carcinogen is the nicotine-derived tobacco-specific nitrosamine, 4(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK). The monoclonal antibody P9D5 induced with a NNK-conjugate vac...
- INSL3 has tumor-promoting activity in thyroid cancer
[作者：Hombach-Klonisch, S; Bialek, J; Radestock, Y; Truong, A; Agoulnik, AI; Fiebig, B; Willing, C; Weber, E; Hoang-Vu, C; Klonisch, T,期刊：International Journal of Cancer, 页码：521-531 , 文章类型： Article，,卷期：2010年127-3]
- The functional role of INSL3 and its receptor RXFP2 in carcinogenesis is largely unknown. We have previously demonstrated (pro-)cathepsin-L as a target of INSL3 in human thyroid cancer cells facilitating penetration of t...
- Modulation of hyaluronan production by CD44 positive glioma cells
[作者：Wiranowska, M; Ladd, S; Moscinski, LC; Hill, B; Haller, E; Mikecz, K; Plaas, A,期刊：International Journal of Cancer, 页码：532-542 , 文章类型： Article，,卷期：2010年127-3]
- This study examines the functional relationship between glioma cell production of hyaluronan (HA), known to play a role in glioma invasion, expression of its CD44 receptor, and glioma cell viability. Production of HA by ...
- Phosphatase of regenerating liver-3 as a convergent therapeutic target for lymph node metastasis in esophageal squamous cell carcinoma
[作者：Ooki, A; Yamashita, K; Kikuchi, S; Sakuramoto, S; Katada, N; Watanabe, M,期刊：International Journal of Cancer, 页码：543-554 , 文章类型： Article，,卷期：2010年127-3]
- Phosphatase of regenerating liver-3 (PRL-3) is a molecule associated with metastasis in a diverse of cancers, which, however, remains largely unknown in esophageal squamous cell carcinoma (ESCC). We examined both the cli...
- Epigenetic silencing of SFRP5 is related to malignant phenotype and chemoresistance of ovarian cancer through Wnt signaling pathway
[作者：Su, HY; Lai, HC; Lin, YW; Liu, CY; Chen, CK; Chou, YC; Lin, SP; Lin, WC; Lee, HY; Yu, MH,期刊：International Journal of Cancer, 页码：555-567 , 文章类型： Article，,卷期：2010年127-3]
- Oncogenic activation of the Wnt signaling pathway is common in cancers, but mutation of beta-catenin in ovarian cancer is rare. In addition to genetic events, epigenetic modification of secreted frizzled-related protein ...
- Loss of imprinting and marked gene elevation are 2 forms of aberrant IGF2 expression in colorectal cancer
[作者：Cheng, YW; Idrees, K; Shattock, R; Khan, SA; Zeng, ZS; Brennan, CW; Paty, P; Barany, F,期刊：International Journal of Cancer, 页码：568-577 , 文章类型： Article，,卷期：2010年127-3]
- Loss of imprinting (LOI) of insulin-like growth factor 2 (IGF2) is a common event in many cancers and typically activates the maternally silenced allele. The resulting biallelic IGF2 expression correlates strongly with t...
- Mutations in TP53 tumor suppressor gene in wood dust-related sinonasal cancer
[作者：Holmila, R; Bornholdt, J; Heikkila, P; Suitiala, T; Fevotte, J; Cyr, D; Hansen, J; Snellman, SM; Dictor, M; Steiniche, T; Schlunssen, V; Schneider, T; Pukkala, E; Savolainen, K; Wolff, H; Wallin, H; Luce, D; Husgafvel-Pursiainen, K,期刊：International Journal of Cancer, 页码：578-588 , 文章类型： Article，,卷期：2010年127-3]
- The causal role of work-related exposure to wood dust in the development of sinonasal cancer has long been established by numerous epidemiologic studies. To study molecular changes in these tumors, we analyzed TP53 gene ...
- Single nucleotide polymorphisms in miRNA binding sites and miRNA genes as breast/ovarian cancer risk modifiers in Jewish high-risk women
[作者：Kontorovich, T; Levy, A; Korostishevsky, M; Nir, U; Friedman, E,期刊：International Journal of Cancer, 页码：589-597 , 文章类型： Article，,卷期：2010年127-3]
- We hypothesized that aberrant gene silencing by miRNA may affect mutant BRCA penetrance. To test this notion, frequency of single nucleotide polymorphisms (SNPs; n = 42) within predicted miRNA binding sites or miRNA prec...
- Recombinant single-chain variable fragment antibodies against extracellular epitopes of human multidrug resistance protein MRP3 for targeting malignant gliomas
[作者：Kuan, CT; Srivastava, N; McLendon, RE; Marasco, WA; Zalutsky, MR; Bigner, DD,期刊：International Journal of Cancer, 页码：598-611 , 文章类型： Article，,卷期：2010年127-3]
- Multidrug resistance protein 3 (MRP3), a multidrug resistance protein identified by serial analysis of gene expression as a glioblastoma multiforme (GBM)-associated molecule, is highly expressed in GBM, but not in normal...
- Circulating free DNA, p53 antibody and mutations of KRAS gene in endometrial cancer
[作者：Dobrzycka, B; Terlikowski, SJ; Mazurek, A; Kowalczuk, O; Niklinska, W; Chyczewski, L; Kulikowski, M,期刊：International Journal of Cancer, 页码：612-621 , 文章类型： Article，,卷期：2010年127-3]
- This study was conducted to evaluate the significance of circulating free DNA (CFDNA), p53 antibody (p53-Ab) and mutations of KRAS gene in the development of endometrial cancer (EC). A total of 109 patients with EC (87 p...
- Type-specific human papillomavirus oncogene messenger RNA levels correlate with the severity of cervical neoplasia
[作者：Ho, CM; Lee, BH; Chang, SF; Chien, TY; Huang, SH; Yan, CC; Cheng, WF,期刊：International Journal of Cancer, 页码：622-632 , 文章类型： Article，,卷期：2010年127-3]
- This study aimed to evaluate whether quantitation of high-risk human papillomavirus (HR-HPV) E6 messenger RNA (mRNA) can be a potential biomarker for detecting the severity of cervical lesions. HPV genotyping was perform...
- Tonsillitis, tonsillectomy and Hodgkin's lymphoma
[作者：Vestergaard, H; Westergaard, T; Wohlfahrt, J; Hjalgrim, H; Melbye, M,期刊：International Journal of Cancer, 页码：633-637 , 文章类型： Article，,卷期：2010年127-3]
- It has been debated whether the reported increased risk of Hodgkin's lymphoma (HL) after tonsillectomy could be due to some underlying factor rather than the surgery itself. We studied whether not only tonsillectomy but ...
- Fluid intake and the risk of bladder cancer: results from the South and East China case-control study on bladder cancer
[作者：Hemelt, M; Hu, ZQ; Zhong, ZH; Xie, LP; Wong, YC; Tam, PC; Cheng, KK; Ye, ZQ; Bi, XC; Lu, QA; Mao, YQ; Zhong, WD; Zeegers, MP,期刊：International Journal of Cancer, 页码：638-645 , 文章类型： Article，,卷期：2010年127-3]
- Although several studies have assessed the association between total fluid intake, specific drinks and bladder cancer, no firm conclusions can yet be drawn. Four hundred thirty two bladder cancer cases and 392 frequency ...
- Human papillomavirus testing and cervical cytology in primary screening for cervical cancer among women in rural China: comparison of sensitivity, specificity, and frequency of referral
[作者：Moy, LM; Zhao, FH; Li, LY; Ma, JF; Zhang, QM; Chen, F; Song, Y; Hu, SY; Balasubramanian, A; Pan, QJ; Koutsky, L; Zhang, WH; Lim, JM; Qiao, YL; Sellors, JW,期刊：International Journal of Cancer, 页码：646-656 , 文章类型： Article，,卷期：2010年127-3]
- The causal relationship between persistent high-risk human papillomavirus infection and cervical cancer is widely accepted. HR-HPV DNA testing, alone or in combination with Pap smear testing, may have a role in primary s...
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