- Prognostic significance and therapeutic potential of eukaryotic translation initiation factor 5A (eIF5A) in hepatocellular carcinoma
[作者:Lee, NP; Tsang, FH; Shek, FH; Mao, M; Dai, HY; Zhang, CS; Dong, SS; Guan, XY; Poon, RTP; Luk, JM,期刊:International Journal of Cancer, 页码:968-976 , 文章类型: Article,,卷期:2010年127-4]
- Using comparative proteomic and genomic approaches, the authors identified eukaryotic translation initiation factor 5A (eIF5A) as an oncofetal molecule highly abundant in mouse embryonic livers and human hepatocellular c...
- Overexpression of DDB2 enhances the sensitivity of human ovarian cancer cells to cisplatin by augmenting cellular apoptosis
[作者:Barakat, BM; Wang, QE; Han, CH; Milum, K; Yin, DT; Zhao, Q; Wani, G; Arafa, ESA; El-Mahdy, MA; Wani, AA,期刊:International Journal of Cancer, 页码:977-988 , 文章类型: Article,,卷期:2010年127-4]
Cisplatin is one of the most widely used anticancer agents, displaying activity against a wide variety of tumors. However, development of drug resistance presents a challenging barrier to successful cancer treatment b...
- Prognostic significance of regulatory T cells in tumor
[作者:Wilke, CM; Wu, K; Zhao, ED; Wang, GB; Zou, WP,期刊:International Journal of Cancer, 页码:748-758 , 文章类型: Article,,卷期:2010年127-4]
- Since entering the immunological stage several decades ago, regulatory T cell biology has been realized as fundamentally important in the prevention of autoimmune conditions, induction of transplant tolerance and the imm...
- The anticancer effect of probiotic Bacillus polyfermenticus on human colon cancer cells is mediated through ErbB2 and ErbB3 inhibition
[作者:Ma, EL; Choi, YJ; Choi, J; Pothoulakis, C; Rhee, SH; Im, E,期刊:International Journal of Cancer, 页码:780-790 , 文章类型: Article,,卷期:2010年127-4]
- A wealth of data implicates that ErbB receptors have essential roles in tumor development. Probiotic bacteria are known to exert an anticancer activity in animal studies. Bacillus polyfermenticus (B.P.), a probiotic bact...
- Early and late effects of the immunosuppressants rapamycin and mycophenolate mofetil on UV carcinogenesis
[作者:de Gruijl, FR; Koehl, GE; Voskamp, P; Strik, A; Rebel, HG; Gaumann, A; de Fijter, JW; Tensen, CP; Bavinck, JNB; Geissler, EK,期刊:International Journal of Cancer, 页码:796-804 , 文章类型: Article,,卷期:2010年127-4]
- Increased skin cancer risk in organ transplant recipients has been experimentally emulated with enhanced UV carcinogenesis from administering conventional immunosuppressants. However, newer generation immunosuppressive d...
- Nerve invasion distance is dependent on laminin gamma 2 in tumors of pancreatic cancer
[作者:Mitsunaga, S; Fujii, S; Ishii, G; Kinoshita, T; Hasebe, T; Aoyagi, K; Sasaki, H; Ochiai, A,期刊:International Journal of Cancer, 页码:805-819 , 文章类型: Article,,卷期:2010年127-4]
- The distance of nerve invasion is an important prognostic factor in pancreatic cancer. The extracellular matrix (ECM) of nerve, mainly composed of laminin, collagen IV and anchoring fibrils, might affect nerve invasion. ...
- ERK/MAPK activation involves hypoxia-induced MGr1-Ag/37LRP expression and contributes to apoptosis resistance in gastric cancer
[作者:Liu, LL; Zhang, HB; Sun, L; Gao, YQ; Jin, HF; Liang, SH; Wang, YX; Dong, MQ; Shi, YQ; Li, ZC; Fan, DM,期刊:International Journal of Cancer, 页码:820-829 , 文章类型: Article,,卷期:2010年127-4]
- We previously demonstrated that hypoxia increased the hypoxia-inducible factor (HIF-1)-dependent MGr1-Ag/37LRP expression, which enhanced adhesion of gastric cancer cells to laminin, inhibited drug-induced apoptosis and ...
- Down-regulation of type I interferon receptor sensitizes bladder cancer cells to vesicular stomatitis virus-induced cell death
[作者:Zhang, KX; Matsui, Y; Hadaschik, BA; Lee, C; Jia, W; Bell, JC; Fazli, L; So, AI; Rennie, PS,期刊:International Journal of Cancer, 页码:830-838 , 文章类型: Article,,卷期:2010年127-4]
- The intrinsic oncolytic specificity of vesicular stomatitis virus (VSV) is currently being exploited to develop alternative therapeutic strategies for bladder cancer and other cancers. Previously we reported that oncolyt...
- A novel role of gap junction connexin46 protein to protect breast tumors from hypoxia
[作者:Banerjee, D; Gakhar, G; Madgwick, D; Hurt, A; Takemoto, D; Nguyen, TA,期刊:International Journal of Cancer, 页码:839-848 , 文章类型: Article,,卷期:2010年127-4]
- Connexin proteins are the principle structural components of the gap junctions. Colocalization and tissue-specific expression of diverse connexin molecules are reported to occur in a variety of organs. Impairment of gap ...
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