- Indeno[1,2-c]isoquinolin-5,11-diones conjugated to amino acids: Synthesis, cytotoxicity, DNA interaction, and topoisomerase II inhibition properties
[作者:AHN GANG; LANSIAUX AMELIE; GOOSSENS JEANFRANCOIS; BAILLY CHRISTIAN; BALDEYROU BRIGITTE; SCHIFANOFAUX NADEGE; GRANDCLAUDON PIERRE; COUTURE AXEL; RYCKEBUSCH ADINA,期刊:Bioorganic & Medicinal Chemistry, 页码:8119-8133 , 文章类型: Article,,卷期:2010年18-22]
- Three series of indeno[1,2-c]isoquinolin-5,11-dione-amino acid conjugates were designed and synthesized. Amino acids were connected to the tetracycle through linkers with lengths of n = 2 and 3 atoms using ester (series ...
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