- Humanized monoclonal antibodies derived from chimpanzee Fabs protect against Japanese encephalitis virus in vitro and in vivo
[作者:Goncalvez, AP; Chien, CH; Tubthong, K; Gorshkova, I; Roll, C; Donau, O; Schuck, P; Yoksan, S; Wang, SD; Purcell, RH; Lai, CJ,期刊:Journal of virology, 页码:7009-7021 , 文章类型: Article,,卷期:2008年82-14]
- Japanese encephalitis virus (JEV)-specific Fab antibodies were recovered by repertoire cloning from chimpanzees initially immunized with inactivated JE-VAX and then boosted with attenuated JEV SA14-14-2. From a panel of ...
- Monitoring early fusion dynamics of human immunodeficiency virus type 1 at single-molecule resolution
[作者:Dobrowsky, TM; Zhou, Y; Sun, SX; Siliciano, RF; Wirtz, D,期刊:Journal of virology, 页码:7022-7033 , 文章类型: Article,,卷期:2008年82-14]
- The fusion of human immunodeficiency virus type 1 (HIV-1) to host cells is a dynamic process governed by the interaction between glycoproteins on the viral envelope and the major receptor, CD4, and coreceptor on the surf...
- Qualitative and quantitative characteristics of rotavirus-specific CD8 T cells vary depending on the route of infection
[作者:Jiang, JQ; He, XS; Feng, N; Greenberg, HB,期刊:Journal of virology, 页码:6812-6819 , 文章类型: Article,,卷期:2008年82-14]
- CD8 T-cell response provides an important defense against rotavirus, which infects a variety of systemic locations in addition to the gut. Here we investigated the distribution, phenotype, and function of rotavirus-speci...
- Annexin II incorporated into influenza virus particles supports virus replication by converting plasminogen into plasmin
[作者:LeBouder, F; Morello, E; Rimmelzwaan, GF; Bosse, F; Pechoux, C; Delmas, B; Riteau, B,期刊:Journal of virology, 页码:6820-6828 , 文章类型: Article,,卷期:2008年82-14]
- For influenza viruses to become infectious, the proteolytic cleavage of hemagglutinin (HA) is essential. This usually is mediated by trypsin-like proteases in the respiratory tract. The binding of plasminogen to influenz...
- Differential antigen requirements for protection against systemic and intranasal vaccinia virus challenges in mice
[作者:Kaufman, DR; Goudsmit, J; Holterman, L; Ewald, BA; Denholtz, M; Devoy, C; Giri, A; Grandpre, LE; Heraud, JM; Franchini, G; Seaman, MS; Havenga, MJE; Barouch, DH,期刊:Journal of virology, 页码:6829-6837 , 文章类型: Article,,卷期:2008年82-14]
- The development of a subunit vaccine for smallpox represents a potential strategy to avoid the safety concerns associated with replication-competent vaccinia virus. Preclinical studies to date with subunit smallpox vacci...
- Cross-reactive human immunodeficiency virus type 1-neutralizing human monoclonal antibody that recognizes a novel conformational epitope on gp41 and lacks reactivity against self-antigens
[作者:Zhang, MY; Vu, BK; Choudhary, A; Lu, H; Humbert, M; Ong, H; Alam, M; Ruprecht, RM; Quinnan, G; Jiang, S; Montefiori, DC; Mascola, JR; Broder, CC; Haynes, BF; Dimitrov, DS,期刊:Journal of virology, 页码:6869-6879 , 文章类型: Article,,卷期:2008年82-14]
- Broadly cross-reactive human immunodeficiency virus (HIV)-neutralizing antibodies are infrequently elicited in infected humans. The two best-characterized gp41-specific cross-reactive neutralizing human monoclonal antibo...
- Synthesis of genomic and subgenomic RNA in mosquito cells infected with two Sindbis virus nsP4 mutants: Influence of intracellular nucleoside triphosphate concentrations
[作者:Li, ML; Kwan, TY; Simmonds, HA; Stollar, V,期刊:Journal of virology, 页码:6880-6888 , 文章类型: Article,,卷期:2008年82-14]
- Cells infected with Sindbis virus (SV) make two positive-strand RNAs, a genomic-length RNA (G) RNA and a subgenomic (SG) RNA. In cells infected with SVstd, and in general in cells infected with wt alphaviruses, more SG R...
- Cdc34p ubiquitin-conjugating enzyme is a component of the tombusvirus replicase complex and ubiquitinates p33 replication protein
[作者:Li, ZH; Barajas, D; Panavas, T; Herbst, DA; Nagy, PD,期刊:Journal of virology, 页码:6911-6926 , 文章类型: Article,,卷期:2008年82-14]
- To identify host proteins interacting with Tomato bushy stunt virus (TBSV) replication proteins in a genome-wide scale, we have used a yeast (Saccharomyces cerevisiae) proteome microarray carrying 4,088 purified proteins...
- A tetravalent dengue vaccine based on a complex adenovirus vector provides significant protection in rhesus monkeys against all four serotypes of dengue virus
[作者:Raviprakash, K; Wang, D; Ewing, D; Holman, DH; Block, K; Woraratanadharm, J; Chen, L; Hayes, C; Dong, JY; Porter, K,期刊:Journal of virology, 页码:6927-6934 , 文章类型: Article,,卷期:2008年82-14]
- Nearly a third of the human population is at risk of infection with the four serotypes of dengue viruses, and it is estimated that more than 100 million infections occur each year. A licensed vaccine for dengue viruses h...
- Blocking antibody access to neutralizing domains on glycoproteins involved in entry as a novel mechanism of immune evasion by herpes simplex virus type 1 glycoproteins C and E
[作者:Hook, LM; Huang, JL; Jiang, M; Hodinka, R; Friedman, HM,期刊:Journal of virology, 页码:6935-6941 , 文章类型: Article,,卷期:2008年82-14]
- Herpes simplex virus type 1 (HSV-1) glycoprotein C (gC) blocks complement activation, and glycoprotein E (gE) interferes with IgG Fc-mediated activities. While evaluating gC- and gE-mediated immune evasion in human immun...
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