- Design and Expression of a Dimeric Form of Human Immunodeficiency Virus Type 1 Antibody 2G12 with Increased Neutralization Potency
[作者:West, AP; Galimidi, RP; Foglesong, CP; Gnanapragasam, PNP; Huey-Tubman, KE; Klein, JS; Suzuki, MD; Tiangco, NE; Vielmetter, J; Bjorkman, PJ,期刊:Journal of virology, 页码:98-104 , 文章类型: Article,,卷期:2008年83-1]
- The antigen-binding fragment of the broadly neutralizing human immunodeficiency virus type 1 (HIV-1) antibody 2G12 has an unusual three-dimensional (3D) domain-swapped structure with two aligned combining sites that faci...
- Differing Roles of Inner Tegument Proteins pUL36 and pUL37 during Entry of Herpes Simplex Virus Type 1
[作者:Roberts, APE; Abaitua, F; O'Hare, P; McNab, D; Rixon, FJ; Pasdeloup, D,期刊:Journal of virology, 页码:105-116 , 文章类型: Article,,卷期:2008年83-1]
- Studies with herpes simplex virus type 1 (HSV-1) have shown that secondary envelopment and virus release are blocked in mutants deleted for the tegument protein gene UL36 or UL37, leading to the accumulation of DNA-conta...
- Interaction of the Influenza A Virus Nucleocapsid Protein with the Viral RNA Polymerase Potentiates Unprimed Viral RNA Replication
[作者:Newcomb, LL; Kuo, RL; Ye, QZ; Jiang, YY; Tao, YZJ; Krug, RM,期刊:Journal of virology, 页码:29-36 , 文章类型: Article,,卷期:2008年83-1]
- The influenza A virus polymerase transcribes and replicates the eight virion RNA (vRNA) segments. Transcription is initiated with capped RNA primers excised from cellular pre-mRNAs by the intrinsic endonuclease of the vi...
- Association of Simian Virus 40 Vp1 with 70-Kilodalton Heat Shock Proteins and Viral Tumor Antigens
[作者:Li, PP; Itoh, N; Watanabe, M; Shi, YF; Liu, PN; Yang, HJ; Kasamatsu, H,期刊:Journal of virology, 页码:37-46 , 文章类型: Article,,卷期:2008年83-1]
- Proper folding of newly synthesized viral proteins in the cytoplasm is a prerequisite for the formation of infectious virions. The major capsid protein Vp1 of simian virus 40 forms a series of disulfide-linked intermedia...
- Simian Virus 40 Large T Antigen Disrupts Genome Integrity and Activates a DNA Damage Response via Bub1 Binding
[作者:Hein, J; Boichuk, S; Wu, JP; Cheng, Y; Freire, R; Jat, PS; Roberts, TM; Gjoerup, OV,期刊:Journal of virology, 页码:117-127 , 文章类型: Article,,卷期:2008年83-1]
- Simian virus 40 (SV40) large T antigen (LT) is a multifunctional protein that is important for viral replication and oncogenic transformation. Previously, infection of monkey or human cells with SV40 was shown to lead to...
- Antiviral Activity of the Zinc Ionophores Pyrithione and Hinokitiol against Picornavirus Infections
[作者:Krenn, BM; Gaudernak, E; Holzer, B; Lanke, K; Van Kuppeveld, FJM; Seipelt, J,期刊:Journal of virology, 页码:58-64 , 文章类型: Article,,卷期:2008年83-1]
- We have discovered two metal ion binding compounds, pyrithione (PT) and hinokitiol (HK), that efficiently inhibit human rhinovirus, coxsackievirus, and mengovirus multiplication. Early stages of virus infection are unaff...
- HLA-Associated Alterations in Replication Capacity of Chimeric NL4-3 Viruses Carrying gag-protease from Elite Controllers of Human Immunodeficiency Virus Type 1
[作者:Miura, T; Brockman, MA; Brumme, ZL; Brumme, CJ; Pereyra, F; Trocha, A; Block, BL; Schneidewind, A; Allen, TM; Heckerman, D; Walker, BD,期刊:Journal of virology, 页码:140-149 , 文章类型: Article,,卷期:2008年83-1]
- Human immunodeficiency virus type 1 (HIV-1)-infected persons who maintain plasma viral loads of <50 copies RNA/ml without treatment have been termed elite controllers (EC). Factors contributing to durable control of HIV ...
- Evaluation of Live Attenuated Influenza A Virus H6 Vaccines in Mice and Ferrets
[作者:Chen, ZY; Santos, C; Aspelund, A; Gillim-Ross, L; Jin, H; Kemble, G; Subbarao, K,期刊:Journal of virology, 页码:65-72 , 文章类型: Article,,卷期:2008年83-1]
- Avian influenza A virus A/teal/HK/W312/97 (H6N1) possesses seven gene segments that are highly homologous to those of highly pathogenic human influenza H5N1 viruses, suggesting that a W312-like H6N1 virus might have been...
- The Cationic Properties of SEVI Underlie Its Ability To Enhance Human Immunodeficiency Virus Infection
[作者:Roan, NR; Munch, J; Arhel, N; Mothes, W; Neidleman, J; Kobayashi, A; Smith-McCune, K; Kirchhoff, F; Greene, WC,期刊:Journal of virology, 页码:73-80 , 文章类型: Article,,卷期:2008年83-1]
- Human semen contains peptides capable of forming amyloid fibrils termed semen-derived enhancer of viral infection (SEVI) that can greatly increase human immunodeficiency virus (HIV) infection. While SEVI appears to enhan...
- Follicular Dendritic Cells and Human Immunodeficiency Virus Type 1 Transcription in CD4(+) T Cells
[作者:Thacker, TC; Zhou, XY; Estes, JD; Jiang, YJ; Keele, BF; Elton, TS; Burton, GF,期刊:Journal of virology, 页码:150-158 , 文章类型: Article,,卷期:2008年83-1]
- HIV replication occurs throughout the natural course of infection in secondary lymphoid tissues and in particular within the germinal centers (GCs), where follicular dendritic cells (FDCs) are adjacent to CD4(+) T cells....
- Immunopathological Basis of Lymphocytic Choriomeningitis Virus-Induced Chorioretinitis and Keratitis
[作者:Zinkernagel, MS; Bolinger, B; Krebs, P; Onder, L; Miller, S; Ludewig, B,期刊:Journal of virology, 页码:159-166 , 文章类型: Article,,卷期:2008年83-1]
- The infection of humans with the rodent-borne lymphocytic choriomeningitis virus (LCMV) can lead to central nervous system disease in adults or severe neurological disease with hydrocephalus and chorioretinitis in childr...
- Human Immunodeficiency Virus-Specific Gamma Interferon Enzyme-Linked Immunospot Assay Responses Targeting Specific Regions of the Proteome during Primary Subtype C Infection Are Poor Predictors of the Course of Viremia and Set Point
[作者:Gray, CM; Mlotshwa, M; Riou, C; Mathebula, T; Rosa, DD; Mashishi, T; Seoighe, C; Ngandu, N; van Loggerenberg, F; Morris, L; Mlisana, K; Williamson, C; Karim, SA,期刊:Journal of virology, 页码:470-478 , 文章类型: Article,,卷期:2008年83-1]
- It is unknown whether patterns of human immunodeficiency virus (HIV)-specific T-cell responses during acute infection may influence the viral set point and the course of disease. We wished to establish whether the magnit...
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